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Source: The Journal of Allergy and Clinical Immunology: In Practice
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Total 4010 results found since Jan 2013.
Anaphylaxis After Hymenoptera Sting: Is It Venom Allergy, A Clonal Disorder, or Both?
Publication date: Available online 7 April 2015 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Mariana C. Castells , Jason L. Hornick , Cem Akin A 47-year-old man presented with loss of consciousness 5 minutes after being stung by a yellow jacket in his backyard. Epinephrine and fluids were required for resuscitation. Allergy evaluation revealed specific IgE to yellow jacket and honeybee, and the patient was started on venom immunotherapy. He had systemic reactions during buildup and a severe anaphylactic episode requiring 3 doses of intramuscular epinephrine at maintenance doses. Immunothe...
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 7, 2015 Category: Allergy & Immunology Source Type: research
The High Impact of Penicillin Allergy Registration in Hospitalized Patients
Conclusions Prevalence of Pen-A registration in hospitalized patients is high, has high impact on antibiotic prescribing, and is associated with a higher risk of readmission. Verification of the Pen-A in hospitalized patients might restrict the use of reserve antibiotics and improve patient outcome.
Source: The Journal of Allergy and Clinical Immunology: In Practice - August 30, 2016 Category: Allergy & Immunology Source Type: research
Allergy profile should be updated after uneventful administration of a penicillin or penicillin-related antibiotic to a patient with penicillin allergy
Publication date: Available online 17 October 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Wesley D. Oliver, Emily L. Heil, Kerri A. Thom, Joseph P. Martinez, Bryan D. Hayes
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 28, 2016 Category: Allergy & Immunology Source Type: research
World Allergy Organization Systemic Allergic Reaction Grading System: Is a Modification Needed?
Publication date: January–February 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 5, Issue 1 Author(s): Linda S. Cox, Mario Sanchez-Borges, Richard F. Lockey There is no universally accepted grading system to classify the severity of systemic allergic reactions (SARs), including anaphylaxis. Although a consensus definition for anaphylaxis was established in 2005, the signs and symptoms required to define a reaction as anaphylaxis are inconsistently applied in research and clinical practice. As a result, it is difficult to compare and evaluate safety outcomes in surveys, clinical practice...
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 4, 2017 Category: Allergy & Immunology Source Type: research
Immunotherapy for Food Allergy: Are We There Yet?
Publication date: March–April 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 5, Issue 2 Author(s): Yael Gernez, Anna Nowak-Węgrzyn Current clinical research focuses on food allergen-specific immunotherapy through oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. Immunotherapy relies on the delivery of gradually increasing doses of specific allergens to induce desensitization (defined as temporary antigen hyporesponsiveness that depends on regular food ingestion) and, ultimately, tolerance (defined as the ability to ingest food without symptoms despite prolonged periods of av...
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 6, 2017 Category: Allergy & Immunology Source Type: research
Statistical Considerations of Food Allergy Prevention Studies
Publication date: March–April 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 5, Issue 2 Author(s): Henry T. Bahnson, George du Toit, Gideon Lack Clinical studies to prevent the development of food allergy have recently helped reshape public policy recommendations on the early introduction of allergenic foods. These trials are also prompting new research, and it is therefore important to address the unique design and analysis challenges of prevention trials. We highlight statistical concepts and give recommendations that clinical researchers may wish to adopt when designing future study p...
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 6, 2017 Category: Allergy & Immunology Source Type: research
Allergen-Specific Immunotherapy for Respiratory Allergy in Children: Unmet Needs and Future Goals
This article critically appraises the most relevant debated issues on allergen-specific immunotherapy in children, focusing on allergen standardization procedures, heterogeneity of clinical studies, and regulatory and pharmacoeconomic aspects.
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 25, 2017 Category: Allergy & Immunology Source Type: research
Temporal Trends in Epinephrine Dispensing and Allergy/Immunology Follow-up Among Emergency Department Anaphylaxis Patients in the United States, 2005-2014
Conclusions Over the past decade, rates of EAI dispensing and A/I follow-up after an ED visit for anaphylaxis have remained low, suggesting that patients may not be prepared to manage future episodes.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 26, 2017 Category: Allergy & Immunology Source Type: research
Latex Allergy: Where Are We Now and How Did We Get There?
This article summarizes nearly 4 decades of work in control of this epidemic and focuses attention on future problems that still require resolution.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2017 Category: Allergy & Immunology Source Type: research
Are Cephalosporins Safe for Use in Penicillin Allergy Without Prior Allergy Evaluation?
Publication date: Available online 22 September 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Eric Macy, Kimberly G. Blumenthal
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 22, 2017 Category: Allergy & Immunology Source Type: research
Primary Prevention of Food Allergy: Translating Evidence from Clinical Trials to Population-Based Recommendations
Publication date: March–April 2018 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 6, Issue 2 Author(s): Paul J. Turner, Dianne E. Campbell, Robert J. Boyle, Michael E. Levin Given the prevalence and impact of childhood food allergy, there is increasing interest in interventions targeting disease prevention. Although interventions such as early introduction of dietary peanut have demonstrated efficacy in a small number of well-conducted randomized clinical trials, evidence for broader effectiveness and successful implementation at a population level is still lacking, although epidemiological d...
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 7, 2018 Category: Allergy & Immunology Source Type: research
Cross-reactive aeroallergens: which need to cross our mind in food allergy diagnosis?
Publication date: Available online 29 August 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Margaretha A. Faber, Athina L. Van Gasse, Ine I. Decuyper, Vito Sabato, Margo M. Hagendorens, Christel Mertens, Chris H. Bridts, Luc S. De Clerck, Didier G. EboAbstractSecondary food allergies due to cross-reactivity between inhalant- and food allergens are a significant and increasing global health issue. Cross-reactive food allergies predominantly involve plant-derived foods resulting from a prior sensitization to cross-reactive components present in pollen (grass, tree, weeds) and natural rubber...
Source: The Journal of Allergy and Clinical Immunology: In Practice - August 29, 2018 Category: Allergy & Immunology Source Type: research
Patient versus allergy specialist interpretation of a negative workup for suspected iodinated contrast media allergy
Publication date: Available online 5 September 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Rik Schrijvers, Christine Breynaert, Jean-Luc Bourrain, Pascal Demoly, Anca Mirela Chiriac
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 5, 2018 Category: Allergy & Immunology Source Type: research
Exploring the diagnosis and profile of cannabis allergy
ConclusionsThe most effective and practical tests to confirm CA are the SPT with a nCan s 3-rich extract and the sIgE rCan s 3. Can s 3 entails a risk of systemic reactions to plant-derived foods and cofactor-mediated reactions. However, as Can s 3 sensitization is not absolute, other cannabis allergens probably play a role.
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 4, 2018 Category: Allergy & Immunology Source Type: research
Efficacy, Safety, and Quality of Life in a Multicenter, Randomized, Placebo-Controlled Trial of Low-Dose Peanut Oral Immunotherapy in Children with Peanut Allergy
We examined the efficacy, safety, immunologic parameters, quality of life (QOL), and burden of treatment (BOT) of low-dose peanut OIT in a multicenter, double-blind, randomized placebo-controlled trial.MethodsA total of 62 children aged 3 to 17 years with IgE-mediated, challenge-proven peanut allergy were randomized (1:1) to receive peanut OIT with a maintenance dose of 125 to 250 mg peanut protein or placebo. The primary outcome was the proportion of children tolerating 300 mg or more peanut protein at oral food challenge (OFC) after 16 months of OIT. We measured the occurrence of adverse events (AEs), immunologic changes...
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 2, 2019 Category: Allergy & Immunology Source Type: research
