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Source: Journal of Southern Medical University
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Total 774 results found since Jan 2013.
Estradiol activates ERK phosphorylation by binding to ER β to inhibit proliferation and promote apoptosis of human chondrocytes
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Mar 25;41(3):336-343. doi: 10.12122/j.issn.1673-4254.2021.03.04.ABSTRACTOBJECTIVE: To explore the effect of estradiol (E2) binding to its receptor ERβ on the proliferation and apoptosis of C28I2 cells.OBJECTIVE: We cloned the sequence of ESR2 into a recombinant adenovirus plasmid (pAd-ESR2) and packaged the plasmid in HEK293 cells. Normal human chondrocyte C28I2 cells were transfected with Ad-ESR2 or small interfering RNA targeting ESR2-siRNA (ESR2-siRNA), and the effects of treatment with DMSO or E2 on the expression of the proteins associated with endoplasmic reticulum (ER) stress and...
Source: Journal of Southern Medical University - April 14, 2021 Category: Universities & Medical Training Authors: M Zhang Y Yang M Liu L Liang R Luo D Yin F Guo Source Type: research
Effects of RNA interference of CTHRC1 on proliferation and apoptosis of thyroid papillary cancer TCP-1 cells < em > in vitro < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Apr 20;41(4):549-554. doi: 10.12122/j.issn.1673-4254.2021.04.10.ABSTRACTOBJECTIVE: To explore the role of CTHRC1 in regulating the proliferation and apoptosis of papillary thyroid cancer cells.OBJECTIVE: Papillary thyroid cancer TPC-1 cells were transfected with a small interfering RNA (siRNA) targeting CTHRC1, with the cells transfected with a scrambled sequence as the negative control. The changes in cell proliferation and apoptosis were assessed using cell counting kit-8 (CCK-8) and flow cytometry with AV/PI double staining, respectively. The expression of c-caspase-3, c-PARP1 and pho...
Source: Journal of Southern Medical University - May 8, 2021 Category: Universities & Medical Training Authors: Z Tang X Ding S Qin C Zhang Source Type: research
Estradiol activates ERK phosphorylation by binding to ER β to inhibit proliferation and promote apoptosis of human chondrocytes
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Mar 25;41(3):336-343. doi: 10.12122/j.issn.1673-4254.2021.03.04.ABSTRACTOBJECTIVE: To explore the effect of estradiol (E2) binding to its receptor ERβ on the proliferation and apoptosis of C28I2 cells.OBJECTIVE: We cloned the sequence of ESR2 into a recombinant adenovirus plasmid (pAd-ESR2) and packaged the plasmid in HEK293 cells. Normal human chondrocyte C28I2 cells were transfected with Ad-ESR2 or small interfering RNA targeting ESR2-siRNA (ESR2-siRNA), and the effects of treatment with DMSO or E2 on the expression of the proteins associated with endoplasmic reticulum (ER) stress and...
Source: Journal of Southern Medical University - April 14, 2021 Category: Universities & Medical Training Authors: M Zhang Y Yang M Liu L Liang R Luo D Yin F Guo Source Type: research
Effects of RNA interference of CTHRC1 on proliferation and apoptosis of thyroid papillary cancer TCP-1 cells < em > in vitro < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Apr 20;41(4):549-554. doi: 10.12122/j.issn.1673-4254.2021.04.10.ABSTRACTOBJECTIVE: To explore the role of CTHRC1 in regulating the proliferation and apoptosis of papillary thyroid cancer cells.OBJECTIVE: Papillary thyroid cancer TPC-1 cells were transfected with a small interfering RNA (siRNA) targeting CTHRC1, with the cells transfected with a scrambled sequence as the negative control. The changes in cell proliferation and apoptosis were assessed using cell counting kit-8 (CCK-8) and flow cytometry with AV/PI double staining, respectively. The expression of c-caspase-3, c-PARP1 and pho...
Source: Journal of Southern Medical University - May 8, 2021 Category: Universities & Medical Training Authors: Z Tang X Ding S Qin C Zhang Source Type: research
