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Source: Immunology Letters

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Total 44 results found since Jan 2013.

Mettl14 sustains FOXP3 expression to promote the differentiation and functions of induced-regulatory T cells via the mTOR signaling pathway
In conclusion, our study revealed that Mettl14 plays a critical role in the development and suppressive function of iTregs in vitro and could thus serve as a regulatory element for stabilizing iTregs in cell-based therapy.PMID:37121553 | DOI:10.1016/j.imlet.2023.04.008
Source: Immunology Letters - April 30, 2023 Category: Allergy & Immunology Authors: Yanzhuo Liu Yinglin Yuan Zili Zhou Xiaomei Jiang Shu He Fan Wei Yuanyuan Cui Lu Yang Gaoping Zhao Source Type: research

Synergistic regulation of microglia differentiation by CD93 and integrin β1 in the rat pneumococcal meningitis model
In conclusion, interaction between integrin β1 and CD93 promotes differentiation of microglia to the M1 phenotype, increases the release of pro-inflammatory factors, and leads to nervous system injury in pneumococcal meningitis.PMID:36336138 | DOI:10.1016/j.imlet.2022.11.001
Source: Immunology Letters - November 6, 2022 Category: Allergy & Immunology Authors: Nana Qiao Jinghui Zhang Ya Zhang Xinjie Liu Source Type: research

Dermcidin-derived polypeptides: DCD(86-103) induced inflammatory reaction in the skin by activation of mast cells via ST2
CONCLUSION: DCD(86-103) may have induced an inflammatory reaction and participated in the occurrence and development of psoriasis.PMID:36191776 | DOI:10.1016/j.imlet.2022.09.008
Source: Immunology Letters - October 3, 2022 Category: Allergy & Immunology Authors: Delu Che Tao Jia Xinyue Zhang Lei Zhang Xueshan Du Yi Zheng Tong Zhou Xiangjing Song Songmei Geng Source Type: research