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Source: Biochemical and Biophysical Research communications
Management: Food and Drug Administration (FDA)
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Total 2 results found since Jan 2013.
DKK1-targeting cholesterol-modified siRNA implication in hair growth regulation
In this report, we have selected a small interfering RNA (siRNA) targeting DKK1 in vitro via qPCR and then tested its efficacy in vivo on the depilated dorsal skin of the mice. The changes in hair growth in different groups were observed over time. Moreover, the visual observation of the hair growth and hematoxylin and eosin (HE) staining showed that DKK1-targeting siRNA reveals non-inferior results compared with the mice treated with the Food and Drug Administration (FDA)-approved, commercially available minoxidil (5%) topical solution that was used as a positive control. Both- positive control and DKK1-targeting siRNA gr...
Source: Biochemical and Biophysical Research communications - May 27, 2023 Category: Biochemistry Authors: Dimitri Papukashvili Cong Liu Nino Rcheulishvili Fengfei Xie Xingyun Wang Shunping Feng Xiu Sun Chi Zhang Yingyu Li Yunjiao He Peng George Wang Source Type: research
