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Knowledge of anaphylaxis management among latin american dentists
Anaphylaxis is a severe and potentially life-threatening disorder that could occur in dental practice and can be triggered by antibiotics, chlorhexidine, local and general anesthetic and latex. The aim of our study is to assess the knowledge of anaphylaxis management among Latin American dentists.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: J. Gallardo Bastidas, H. Mautong, G. Rouillon Borrero, K. Robles-Velasco, B. Intriago, J. Martin-Delgado, I. Cherrez-Ojeda Tags: P018 Source Type: research

A case of anaphylaxis to sugammadex skin prick testing
Sugammadex is a modified gamma-cyclodextrin gaining increasingly common usage as an anesthetic medication for the rapid reversal of the neuromuscular blocking agents rocuronium and vecuronium. While considered safer than traditional reversal agents, sugammadex is becoming more widely recognized as a rare cause of peri-operative anaphylaxis. There are no standardized skin prick testing protocols or commercially available IgE assays for sugammadex, although previous literature has used an undiluted concentration of 100mg/ml for epicutaneous skin testing.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: M. Dittus, B. Navetta-Modrov Tags: M012 Source Type: research

A case of Perioperative Anaphylaxis Presenting as Hereditary Alpha Tryptasemia
A 64-year-old Caucasian male with a past medical history of hypertension, anxiety, arthritis, depression, and hyperlipidemia presented to the operating room (OR) for a planned shoulder graft surgery. He has had multiple prior surgeries without complications. Prior to the procedure he received a local nerve block with Lidocaine and Bupivacaine in the post anesthesia care unit (PACU). Afterwards he was transported to the OR where he received general anesthesia that included the following: Propofol, Cefazolin, Succinylcholine, Midazolam, Rocuronium, Fentanyl, and an inhaled anesthetic.
Source: Annals of Allergy, Asthma and Immunology - March 12, 2022 Category: Allergy & Immunology Authors: Shaunah Ritter, Jarred Bowden, Debendra Pattanaik Source Type: research

M022 a case of perioperative anaphylaxis: high-risk drug allergy testing in the inpatient setting
As multiple medications are often administered simultaneously during anesthesia, determining the etiology of perioperative anaphylaxis is challenging. This is compounded by the lack of validated skin testing. While drug challenges are the definitive means of assessing for IgE-mediated drug allergy, they must be weighed with the risk for developing a severe reaction.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: E. Robbins, S. Gabryszewski, J. Cafone, J. Lee Source Type: research

M040 a child with a rare true allergy to articaine: a case study
Local anesthetics (LA) are commonly used for painful medical procedures. A variety of adverse reactions are often mistakenly attributed to anesthetic allergy, when in reality true allergy to LAs are exceedingly rare. Consequently, these patients lose the benefit from utilizing LA ’s until workup from an allergist can be done.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2020 Category: Allergy & Immunology Authors: S. Mehta, L. Barisciano Source Type: research

M400 managing a case of reported local lidocaine allergy in a pregnant woman during covid-19 pandemic
We report how we diagnosed and managed a case of reported local anesthetic allergy in a high-risk pregnant woman during the COVID-19 pandemic via telemedicine.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2020 Category: Allergy & Immunology Authors: H. Jin, O. Waqar, R. Miller Tags: NEW! COVID-19 Source Type: research

From the pages of AllergyWatch ®
For this issue of From the Pages of Allergy Watch, there are 3 reviews dealing with various aspects of drug allergy, the focus of this month ’s Annals. The first review is from a study published in the Annals last year, which examines the safety of direct provocation challenges for patients with a diagnosis of penicillin allergy. The next review discusses the experience of a Danish allergy clinic on testing and challenging patients wit h a diagnosis of local anesthetic allergy. The last one is a review of data from patients reporting anaphylaxis after omalizumab.
Source: Annals of Allergy, Asthma and Immunology - March 22, 2020 Category: Allergy & Immunology Authors: Vivian Hernandez-Trujillo, John J. Oppenheimer, Stanley M. Fineman Tags: AllergyWatch Source Type: research

From the pages of AllergyWatch
For this issue of From the Pages of Allergy Watch, there are 3 reviews dealing with various aspects of drug allergy, the focus of this month ’s Annals. The first review is from a study published in the Annals last year, which examines the safety of direct provocation challenges for patients with a diagnosis of penicillin allergy. The next review discusses the experience of a Danish allergy clinic on testing and challenging patients wit h a diagnosis of local anesthetic allergy. The last one is a review of data from patients reporting anaphylaxis after omalizumab.
Source: Annals of Allergy, Asthma and Immunology - March 22, 2020 Category: Allergy & Immunology Authors: Vivian Hernandez-Trujillo, John J. Oppenheimer, Stanley M. Fineman Tags: Special Series Source Type: research

M057 anaphylaxis to rocuronium and evidenced lack of cross reactivity with other neuromuscular blocking agents
Neuromuscular blocking agents (NMBA) such as rocuronium, vecuronium, cisatracurium, succinylcholine, etc. are commonly used during anesthesia induction. There are reported cases of perioperative anaphylaxis due to NMBA; however, the cross reactivity between these medications is not well determined.
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: D. Haehn, I. Carrillo-Martin, D. Restrepo, D. Incontri-Abraham, A. Gonzalez-Estrada Source Type: research

M187 prolonged and refractory tongue angioedema post neurological surgery
Tongue angioedema has been reported as a rare complication of posterior cranial fossa surgeries in the neurosurgical and anesthesia literature. The mechanism is largely unclear though postulated not to be histaminergic nor bradykinin associated unlike the majority of angioedema cases.
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: M. Liu, R. Kachru Source Type: research

Delayed and Protracted Allergic Reaction to Oral Lidocaine
We present the first case of a delayed, protracted allergic reaction to oral viscous lidocaine with positive intradermal testing.
Source: Annals of Allergy, Asthma and Immunology - March 12, 2019 Category: Allergy & Immunology Authors: Sanan Neha, Lee Jenny, Baxter Christina, Jeskey Jack, Hostoffer Robert Tags: Letters Source Type: research

P036 A case of anaphylaxis to sevoflurane
Sevoflurane is an inhalational agent commonly used for induction and maintenance of anesthesia. Halogenated gases are not typically recognized to cause peri-operative anaphylaxis.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: G. Sabharwal, F. Ishmael, S. Lin Source Type: research

P219 Isoflurane therapy for severe refractory status asthmaticus in children
Life threatening asthma is characterized by progressive respiratory failure, though early treatment can prevent airway damage. Some patients with status asthmaticus do not respond to more common medications (b2 agonist, magnesium, anticholinergics). Isoflurane, an inhalational anesthetic agent with bronchodilation properties is a possible alternative treatment.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: O. Papadias Feria, M. Gazzaneo Source Type: research

Intraoperative anaphylaxis to bacitracin during scleral buckle surgery
A 63-year-old man with a history of retinal detachment in the right eye repaired by scleral buckle presented with decreased peripheral vision in the left eye and was found to have a macula-sparing retinal detachment in the left eye, for which urgent repair by scleral buckle was recommended. The patient did not take any routine outpatient medications. Preoperative evaluation revealed no history of anesthetic complications, and he denied any drug allergies. He did not receive any preoperative prophylactic antibiotics.
Source: Annals of Allergy, Asthma and Immunology - October 14, 2017 Category: Allergy & Immunology Authors: Juline Caraballo, Elaine Binkley, Ian Han, Amy Dowden Tags: Letter Source Type: research

Management around invasive procedures in mastocytosis
The objective of this article is to provide a comprehensive overview of the actual risk of iatrogenic anaphylaxis and provide recommendations for daily practice.
Source: Annals of Allergy, Asthma and Immunology - August 30, 2017 Category: Allergy & Immunology Authors: Maud A.W. Hermans, Nicolette J.T. Arends, Roy Gerth van Wijk, P. Martin van Hagen, Hanneke C. Kluin-Nelemans, Hanneke N.G. Oude Elberink, Suzanne G.M.A. Pasmans, Paul L.A. van Daele Tags: Review Source Type: research

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