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Likelihood of diagnosis of eosinophilic esophagitis via endoscopy in dysphagia during the covid-19 pandemic
In this study, we sought to investigate whether the COVID-19 pandemic influenced the likelihood of EGD for diagnosis of EoE in patients with dysphagia.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2022 Category: Allergy & Immunology Authors: J. Brennan, K. Yamada, T. Al-Shaikhly, G. Ghaffari Tags: P046 Source Type: research

Non-Invasive Tests for Eosinophilic Esophagitis: Ready for Use?
Objective: To summarize the existing literature for several promising minimallyinvasive tests to measure disease activity in EoE.Data Sources: Literature searches were performed using PubMed. Keyword combinations included eosinophilic esophagitis and minimally-invasive techniques, including the esophageal string test, Cytosponge, transnasal endoscopy, technetiumlabeled heparin, and non-invasive biomarkers.Study Selections: Retrospective and prospective observational studies, peer-reviewed reviews, and systematic reviews were selected.
Source: Annals of Allergy, Asthma and Immunology - October 23, 2021 Category: Allergy & Immunology Authors: Emily C. McGowan, Seema S. Aceves Tags: CME Reviews Source Type: research

Association of initial esophageal eosinophil counts with atopic dermatitis in EoE patients
The estimated prevalence of atopic dermatitis (AD) in esophageal esophagitis (EoE) ranges from 2 –19%.1 We hypothesized that the presence of AD is associated with increased severity of EoE, defined as an increased rate of food impaction, esophageal stricture, or subepithelial fibrosis on biopsy in a cohort of pediatric patients. We further hypothesized that eosinophil counts on endoscopy woul d be higher in patients with EoE and concomitant AD, than in those without AD.
Source: Annals of Allergy, Asthma and Immunology - September 15, 2021 Category: Allergy & Immunology Authors: Aparna Daley, Erik Lehman, Pooja Jhaveri Tags: Letters Source Type: research

Association of initial esophageal eosinophil counts with atopic dermatitis in patients with eosinophilic esophagitis
The estimated prevalence of atopic dermatitis (AD) in patients with eosinophilic esophagitis (EoE) ranges from 2% to 19%.1 We hypothesized that the presence of AD is associated with increased severity of EoE, defined as an increased rate of food impaction, esophageal stricture, or subepithelial fibrosis on biopsy in a cohort of pediatric patients. We further hypothesized that eosinophil counts on endoscopy would be higher in patients with EoE and concomitant AD than in those without AD.
Source: Annals of Allergy, Asthma and Immunology - September 15, 2021 Category: Allergy & Immunology Authors: Aparna Daley, Erik Lehman, Pooja Jhaveri Tags: Letters Source Type: research

M302 development of ige mediated milk allergy post 4-food elimination in a patient with eosinophilic esophagitis
Patient is a 9-year-old male with a history of moderate/severe atopic dermatitis, allergic rhinitis and eosinophilic esophagitis (EoE). He initially presented to an outside gastroenterologist at 3 years of age due to poor growth and picky eating. He had an endoscopy performed, which demonstrated esophageal eosinophilia. At the time of EoE diagnosis, patient was without IgE mediated food allergies, specifically tolerating dairy products regularly without symptoms. His initial management of eosinophilic esophagitis included the 4-food elimination diet.
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: T. Sarin Source Type: research

M175 omalizumab prophylaxis for endoscopy-associated dermographism
Symptomatic dermographism is an inducible form of urticaria that is often difficult to treat. In antihistamine refractory symptomatic dermographism, omalizumab has demonstrated to be efficacious in case reports.
Source: Annals of Allergy, Asthma and Immunology - October 31, 2019 Category: Allergy & Immunology Authors: W. Blackwell, D. Khan Source Type: research

Sublingual immunotherapy and omalizumab cured allergic chronic rhinosinusitis and asthma: coincidence or synergistic effect?
A 21-year-old man with chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and comorbid asthma the last ten years was referred for allergy evaluation. The diagnosis of CRSwNP was based on the patient ’s symptomatology (nasal congestion, atypical facial pain, hyposmia/anosmia), nasal endoscopy, and the objective evidence of mucosal inflammation (complete opacification of the paranasal sinuses on CT-scan that revealed marked mucosal thickening with partial opacification of right maxillary sinus, near complete opacification of left maxillary sinus, and complete opacification of right and left frontal and anterior ethmoi...
Source: Annals of Allergy, Asthma and Immunology - August 20, 2019 Category: Allergy & Immunology Authors: George N. Konstantinou, Elisavet Kaitalidou, Nikos Skoulikaris Tags: Challenging Clinical Cases Source Type: research

Minimally symptomatic patients with eosinophilic esophagitis should still be actively treated-CON
To frame the reader's mind on the topic discussed in this article, I would like to start by presenting a hypothetical (or not so hypothetical) patient case. A 12-year-old boy presents with abdominal pain and nausea and occasional vomiting for the past year. He is seen by a gastroenterology specialist, who performs an upper endoscopy that reveals linear furrowing of the esophagus and 50 eosinophils per high-power field in the proximal esophagus and 40 eosinophils per high-power field in the distal esophagus.
Source: Annals of Allergy, Asthma and Immunology - May 31, 2019 Category: Allergy & Immunology Authors: Jay Adam Lieberman Tags: Pro/Con Debates Source Type: research

OR083 Medication use and drug allergies do not appear more frequent among patients with eosinophilic esophagitis
Acid-suppressive medications may interfere with the peptic digestion of food allergens. This may increase mucosal permeability and contribute to the development of food allergy and Eosinophilic Esophagitis (EOE). We hypothesized that reported acid suppression medication use would be more common in patients with EOE than non-EOE patients undergoing upper endoscopy. We also aimed to determine whether patients with EOE were more likely to report medication allergies.
Source: Annals of Allergy, Asthma and Immunology - October 27, 2017 Category: Allergy & Immunology Authors: L. Rothstein, R. Miller, B. Lebwohl, P. Green, S. Lagana, R. Abdelmessih Source Type: research

Correlation of basophil infiltration in nasal polyps with the severity of chronic rhinosinusitis
Chronic rhinosinusitis (CRS) represents a heterogeneous disease group characterized by local inflammation of the sinonasal tissues.1 It has been defined as symptomatic inflammation of the sinonasal mucosa that lasts more than 12 weeks as confirmed by computed tomography (CT) and nasal endoscopy.2 Generally, CRS is divided into 2 subsets based on endoscopic findings: CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP).3
Source: Annals of Allergy, Asthma and Immunology - October 16, 2014 Category: Allergy & Immunology Authors: Ryoji Kagoya, Kenji Kondo, Shintaro Baba, Makiko Toma-Hirano, Hironobu Nishijima, Keigo Suzukawa, Shu Kikuta, Tatsuya Yamasoba Source Type: research