• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Can't raise one eye brow: does it ring any norwegian bells?
A 60 year old Nigerian man with diabetes who has lived in Europe for 30 years but regularly revisits Nigeria, presented with 6 months of numbness and weakness in all four limbs and recent right facial weakness. Examination revealed partial right facial and left ulnar nerve palsies with areflexia but no skin lesions. Neurophysiology showed multifocal mixed sensory-motor neuropathy with demyelinating features and prominent facial nerve involvement. He was found to be HIV positive. Subsequent examination revealed peripheral nerve thickening confirmed on limb MRI. Nerve biopsy showed chronic endoneuritis and perineuritis, but ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Galtrey, C., Schon, F., Modarres, H., Rossor, A., Lockwood, D., Reilly, M., Manji, H. Tags: Immunology (including allergy), HIV/AIDS, Tropical medicine (infectious diseases), Neuropathology, Radiology, Surgical diagnostic tests ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Case report: a presumptive diagnosis of acute disseminated encephalomyelitis
A 42-year old previously well man presented with a ten-day history of a flu-like illness, headache, back pain and urinary retention. He deteriorated in hospital with pyrexia and agitation and developed acute respiratory compromise necessitating intubation. MR imaging of the neural axis demonstrated enhancement of the leptomeninges, the splenium of the corpus callosum and patchy enhancement of the cervical and thoracic cord. CSF analysis revealed a white cell count of 211 (95% lymphocytes), protein 2.96 g/L and glucose 3.2 mmol/L (serum glucose 9.6 mmol/L). Initial working diagnosis was of a meningoencephalitis with a ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: Al-Ansari, A., Hill, M. Tags: Immunology (including allergy), HIV/AIDS, Meningitis, Cranial nerves, Headache (including migraine), Infection (neurology), Multiple sclerosis, Pain (neurology), Spinal cord, Ophthalmology Thur 21, Parallel session 5: Therapeutics Source Type: research

Ockham's razor or hickam's dictum? the diagnostic journey of a patient with proximal myopathy
A 39-year old Congolese native presented with a ten-year history of myalgia and progressive muscle weakness. He had a known tissue diagnosis of pulmonary, mediastinal and hepatic sarcoidosis, as well as latent tuberculosis. Family history was unavailable. Examination revealed deformity of the distal joints; shoulder girdle and proximal lower limb atrophy; proximal muscle weakness and a waddling gait. CK was 2560 IU/l (normal <290). Plain films of the hands revealed cystic bony change. EMG demonstrated features consistent with a necrotising myopathy. MRI of proximal muscle groups revealed abnormal high signal consistent ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: O'Dowd, S., Munteanu, T., Hardiman, D., Langan, Y., Brett, F., Redmond, J. Tags: Immunology (including allergy), Muscle disease, Neuromuscular disease, Radiology, Musculoskeletal syndromes, Surgical diagnostic tests Thur 21, Parallel session 5: Therapeutics Source Type: research

Why authors use multiple sclerosis in novels, plays and short stories?
MS is a relatively new disease probably first described in 1843 by an English aristocrat Sir Augustus C'Este'. Earlier description of symptoms typical of MS such as Lidwina Von Schiedan of Holland 1880–1933 are considered doubtful. In order to indentify fictional characters suffering from MS I have first – in 1996-used literary works similar to me; later the internet was searched. After locating fictional people with MS I have written to the authors themselves or to their publishers inquiring the reason they used MS. Several of my enquiry letters remained unanswered possibly undelivered-(attempts are now made t...
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 13, 2015 Category: Neurosurgery Authors: Elian, M. Tags: Genetics, Immunology (including allergy), Multiple sclerosis, Musculoskeletal syndromes MEMBERS ' POSTERS Source Type: research

A case of 'ping-pong' gaze of unknown cause
A 66 year-old Indian gentleman with a background of type II diabetes, Crohn's disease and previously treated tuberculosis presented with double vision and unsteadiness. He was found to have a right-sided internuclear opthalmoplegia (INO) along with weakness and fasciculations in the lower limbs associated with brisk reflexes and an ataxic gait. An MRI scan of the brain and spinal cord revealed multiple supratentorial and infratentorial lesions. There was a hyperintensity in the right medial longitudinal fasciculus, which was felt to explain the INO. Cord and nerve root changes were also present. A CT angiogram of the brain...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Bedford, J. Tags: Immunology (including allergy), Brain stem / cerebellum, Coma and raised intracranial pressure, Neurological injury, Trauma CNS / PNS, Ophthalmology, Radiology, Radiology (diagnostics), Trauma, Injury Association of British Neurologists (ABN) joint meet Source Type: research