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Specialty: Allergy & Immunology
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Total 828 results found since Jan 2013.
Nrf2 regulates the expression of NOX1 in TNF- α-induced A549 cells
In this study, we analyzed the potential regulatory role of nuclear factor erythroid-2-related factor 2 (Nrf2) on NADPH oxidase 1 (NOX1) in tumor necrosis factor-α (TNF-α)-induced inflammation and oxidative stress in human type II alveolar epithelial cells. In this study, A549 cells were transfected with Nrf2 siRNA and overexpression vectors for 6 h before being induced by TNF-α for 24 h. TNF-α upregulated the expression of NOX1 and Nrf2 in A549 cells. Furthermore, overexpression of Nrf2 could reduce TNF-α-induced NF-κB mRNA and protein expression after transfection with the Nrf2 siRNA vector, and the levels of IL-6,...
Source: Allergologia et Immunopathologia - January 9, 2023 Category: Allergy & Immunology Authors: Weijing Wu Jiamin Zhang Xiaoshan Su Xiaoping Lin Li Zhu Zesen Zhuang Chennan Liu Zhixing Zhu Yiming Zeng Source Type: research
