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Source: World Journal of Gastroenterology : WJG
Education: Study
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Total 64 results found since Jan 2013.
Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma < em > via < /em > the PI3K/AKT pathway
CONCLUSION: Our study suggests for the first time that DDX51 promotes cancer cell proliferation by regulating the PI3K/AKT pathway; thus, DDX51 might be a therapeutic target for ESCC.PMID:35125830 | PMC:PMC8790558 | DOI:10.3748/wjg.v28.i4.464
Source: World Journal of Gastroenterology : WJG - February 7, 2022 Category: Gastroenterology Authors: Dong-Xin Hu Qi-Feng Sun Lin Xu Hong-Da Lu Fan Zhang Zhen-Miao Li Ming-Yan Zhang Source Type: research
Reactive oxygen species-induced activation of Yes-associated protein-1 through the c-Myc pathway is a therapeutic target in hepatocellular carcinoma.
CONCLUSION: This study shows a novel connection between YAP-1 and the UPR through the c-Myc pathway during oxidative stress in HCC. The ROS-induced activation of YAP-1 via the c-Myc pathway, which leads to the activation of the UPR pathway, might be a therapeutic target in HCC.
PMID: 33268949 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - November 14, 2020 Category: Gastroenterology Authors: Cho Y, Park MJ, Kim K, Kim SW, Kim W, Oh S, Lee JH Tags: World J Gastroenterol Source Type: research
