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There ’s a shortage of monkeypox vaccine. Could one dose instead of two suffice?
As the monkeypox outbreak grows, the preferred vaccine to combat it is in short supply—a problem that’s only getting worse now that countries are expanding access to the vaccine. But there is a strategy that could double overnight the number of people who can be vaccinated: use a single shot instead of the recommended two. Compelling data from monkey and human studies suggest a single dose of the vaccine—produced by Bavarian Nordic and sold under three different brand names—solidly protects against monkeypox, and that the second dose mainly serves to extend the durability of protection. The United Kingdom...
Source: Science of Aging Knowledge Environment - July 1, 2022 Category: Geriatrics Source Type: research

Expanding Research Capacity in Sub-Saharan Africa Through Informatics, Bioinformatics, and Data Science Training Programs in Mali
Conclusion Bioinformatics and data science training programs in developing countries necessitate incremental and collaborative strategies for their feasible and sustainable development. The progress described here covered decades of collaborative efforts centered on training and research on computationally intensive topics. These efforts laid the groundwork and platforms conducive for hosting a bioinformatics and data science training program in Mali. Training programs are perhaps best facilitated through Africa’s university systems as they are perhaps best positioned to maintain core resources during lapses in sho...
Source: Frontiers in Genetics - April 11, 2019 Category: Genetics & Stem Cells Source Type: research

Evaluation of IL-12RB1, IL-12B, CXCR-3 and IL-17a expression in cases affected by a non-healing form of cutaneous leishmaniasis: an observational study design
This study has been approved by a local ethical committee. The final results will be disseminated through peer-reviewed journals and scientific conferences.
Source: BMJ Open - January 26, 2017 Category: Journals (General) Authors: Moafi, M., Rezvan, H., Sherkat, R., Taleban, R., Asilian, A., Zarkesh Esfahani, S. H., Nilforoushzadeh, M. A., Jaffary, F., Feizi, A. Tags: Open access, Dermatology, Immunology (including allergy), Infectious diseases Protocol Source Type: research