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Infectious Disease: HIV AIDS
Drug: Atorvastatin Calcium
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Atorvastatin restricts HIV replication in CD4+ T cells by upregulation of p21
Conclusion: The results demonstrate a novel mechanism by which atorvastatin induced resistance of CD4+ T cells to HIV-1 infection via p21 upregulation and suggest that statins may hold particular promise for some HIV-infected individuals.
Source: AIDS - December 23, 2015 Category: Infectious Diseases Tags: Basic Science Source Type: research