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Total 6685 results found since Jan 2013.
Whole-genome analysis of < em > Haemophilus influenzae < /em > strains isolated from persons with cystic fibrosis
Conclusion. The H. influenzae strains showed limited levels of resistance, with the highest being against co-trimoxazole. Sequences encoding a carbamate kinase and a haemoglobin- and haemoglobin-haptoglobin-binding-like protein, a glycosyl transferase and an urease may aid the colonization of the CF lung. The adhesins and other identified putative virulence factors did not seem to be necessary for colonization.PMID:36006824 | DOI:10.1099/jmm.0.001570
Source: Journal of Medical Microbiology - August 25, 2022 Category: Microbiology Authors: Ad C Fluit Jumamurat R Bayjanov Barry J Benaissa-Trouw Malbert R C Rogers Mar ía Díez-Aguilar Rafael Cant ón Michael M Tunney J Stuart Elborn Miquel B Ekkelenkamp Source Type: research
Antimicrobial resistance and molecular characterization of gene cassettes from class 1 integrons in < em > Salmonella < /em > strains
Conclusion. The integron and the drug resistance genes carried by integron have a certain relationship with drug resistance.PMID:36069773 | DOI:10.1099/jmm.0.001574
Source: Journal of Medical Microbiology - September 7, 2022 Category: Microbiology Authors: Jie Ma Na An Wanxiang Li Mi Liu Shirong Li Source Type: research
Rapid fluoroquinolone resistance detection in < em > Pseudomonas aeruginosa < /em > using mismatch amplification mutation assay-based real-time PCR
Conclusions. Our GyrA SYBR-MAMAs provide a rapid and cost-effective method for same-day identification of FQ AMR in P. aeruginosa. An additional SYBR-MAMA targeting the GyrB S466Y/S466F variants would increase FQ AMR prediction to 91 %. Clinical implementation of our assays will permit more timely treatment alterations in cases where decreased FQ susceptibility is identified, leading to improved patient outcomes and antimicrobial stewardship.PMID:36301593 | DOI:10.1099/jmm.0.001593
Source: Journal of Medical Microbiology - October 27, 2022 Category: Microbiology Authors: Danielle E Madden Kate L McCarthy Scott C Bell Olusola Olagoke Timothy Baird Jane Neill Kay A Ramsay Timothy J Kidd Adam G Stewart Shradha Subedi Keat Choong Tamieka A Fraser Derek S Sarovich Erin P Price Source Type: research
Evaluation of synergistic activity of antibiotic combinations in extensive drug-resistant < em > Acinetobacter < /em > species using checkerboard assay
Conclusion. Ampicillin/sulbactam plus amikacin showed the highest synergistic activity followed by ampicillin/sulbactam plus ciprofloxacin. This reflects the value of adding aminoglycosides to either of a β-lactam or quinolone. The tested antibiotic combinations are promising treatment options for XDR-Acinetobacter.PMID:36762530 | DOI:10.1099/jmm.0.001639
Source: Journal of Medical Microbiology - February 10, 2023 Category: Microbiology Authors: Rania M Abdel Halim Sally M Saber Noha Alaa Eldin Fahim Source Type: research
Epidemiology and urological pathogenic potential of < em > Aerococcus < /em > species in greater Glasgow and Clyde (Descriptive study of < em > Aerococcus urinae < /em > in blood culture and urinary samples: clinical importance and potential marker of urinary tract pathology)
Conclusion. A. urinae are emerging pathogens and are likely to become more common due to advances in laboratory technologies and an ageing population. Clinical teams should be aware of their urological pathogenic potential and not dismiss them as contaminants. Whether Aerococcus infection is a potential indicator for undiagnosed urinary tract malignancy warrants further studies.PMID:37335077 | DOI:10.1099/jmm.0.001690
Source: Journal of Medical Microbiology - June 19, 2023 Category: Microbiology Authors: Su Su Htwe Teresa Inkster Source Type: research
Quantifying patient- and hospital-level antimicrobial resistance dynamics in < em > Staphylococcus aureus < /em > from routinely collected data
Conclusion. Within this routinely collected dataset, we found that 65 % of changes in resistance within a patient's S. aureus population could not be explained by antibiotic exposure or between-patient transmission of bacteria, suggesting that within-host evolution via frequent gain and loss of AMR genes may be responsible for these changing AMR profiles. Our study highlights the value of exploring existing routine surveillance data to determine underlying mechanisms of AMR. These insights may substantially improve our understanding of the importance of antibiotic exposure variation, and the success of single S. aureus clo...
Source: Journal of Medical Microbiology - July 11, 2023 Category: Microbiology Authors: Quentin Leclerc Alastair Clements Helen Dunn James Hatcher Jodi A Lindsay Louis Grandjean Gwenan M Knight Source Type: research
