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Triptolide inhibits human breast cancer MCF-7 cell growth via downregulation of the ERα-mediated signaling pathway.
CONCLUSION: The anticancer activity of triptolide against ERα-positive human breast cancer is partially mediated by downregulation of the ERα-mediated signaling pathway.
PMID: 25864647 [PubMed - as supplied by publisher]
Source: Acta Pharmacologica Sinica - April 13, 2015 Category: Drugs & Pharmacology Authors: Li H, Pan GF, Jiang ZZ, Yang J, Sun LX, Zhang LY Tags: Acta Pharmacol Sin Source Type: research