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Prolonged allergen exposure is associated with increased thymic stromal lymphopoietin expression and Th2‐skewing in mouse models of chronic rhinosinusitis
ConclusionsProlonged allergen exposure in ovalbumin/SEB‐induced CRS models maintains Th2 inflammation and reduces Th1 inflammation, which was associated with upregulation of TSLP. Level of EvidenceNA Laryngoscope, 2016
Source: The Laryngoscope - April 22, 2016 Category: ENT & OMF Authors: Dae Woo Kim, Kyoung Mi Eun, Hong Ryul Jin, Seong H. Cho, Dong‐Kyu Kim Tags: Allergy/Rhinology Source Type: research

Sinonasal organized Hematoma: Clinical features of seventeen cases and a systematic review
ConclusionsWe reported 17 cases of OH, including a case of frontal sinus and a case of sphenoid sinus lesion. A large proportion of OH patients had bony destruction of the affected sinus on CT. In these patients, a careful diagnosis should be made to distinguish them from a malignant tumor or other expansile diseases. Level of Evidence4. Laryngoscope, 2015
Source: The Laryngoscope - February 13, 2015 Category: ENT & OMF Authors: Soo Jung Choi, Sung Tae Seo, Ki‐Sang Rha, Yong Min Kim Tags: Allergy/Rhinology Source Type: research

Analysis of comorbidities and objective parameters in refractory chronic rhinosinusitis
ConclusionsThe current analysis constructed the clinical profile of the recalcitrant CRS patient undergoing revision sinus surgery. In general, this patient group has a high prevalence of polyposis, asthma, inhalant allergy, ASA sensitivity, and elevated disease burden as measured by objective measures. The polyp phenotype signifies statistically higher prevalence of associated comorbidities and greater objective disease severity. The presence of asthma, inhalant allergy, and ASA sensitivity also predicts statistically higher disease burden. The endoscopy and CT scores statistically correlate with the number of previous su...
Source: The Laryngoscope - November 26, 2013 Category: ENT & OMF Authors: Pete S. Batra, Liyue Tong, Martin J. Citardi Tags: Triological Society Candidate Thesis Source Type: research

Frontal sinus drillout (modified Lothrop procedure): Long‐term results in 204 patients
ConclusionFor the majority of patients who undergo frontal sinus drillout, patency of the frontal sinus outflow tract appears to be maintained for more than a decade; nevertheless, almost one‐third of patients who undergo this procedure will ultimately require additional frontal sinus surgery. Level of Evidence4. Laryngoscope, 2013
Source: The Laryngoscope - November 13, 2013 Category: ENT & OMF Authors: Jonathan Y. Ting, Arthur Wu, Ralph Metson Tags: Allergy/Rhinology Source Type: research

Aspirin sensitivity does not compromise quality‐of‐life outcomes in patients with samter's triad
ConclusionsAlthough Samter's triad patients present with more severe disease and are more likely to undergo revision surgery, they have postoperative quality‐of‐life outcomes that are comparable to patients with eCRSwP who are not aspirin sensitive. This is the first study to utilize a disease‐specific, validated outcomes instrument in comparing Samter's triad patients with aspirin‐tolerant patients who have nasal polyposis and tissue eosinophilia. Level of Evidence4. Laryngoscope, 2013
Source: The Laryngoscope - June 28, 2013 Category: ENT & OMF Authors: David W. Jang, Brett T. Comer, Vasileios A. Lachanas, Stilianos E. Kountakis Tags: Allergy/Rhinology Source Type: research

Aspirin sensitivity does not compromise quality of life outcomes in patients with Samter's triad
ConclusionAlthough Samter's triad patients present with more severe disease and are more likely to undergo revision surgery, they have postoperative quality‐of‐life outcomes that are comparable to patients with eCRSwP who are not aspirin sensitive. This is the first study to utilize a disease‐specific, validated outcomes instrument in comparing Samter's triad patients with aspirin tolerant patients who have nasal polyposis and tissue eosinophilia.
Source: The Laryngoscope - May 27, 2013 Category: ENT & OMF Authors: David W. Jang, Brett T. Comer, Vasileios Lachanas, Stilianos E. Kountakis Tags: Allergy/Rhinology Source Type: research