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Drug: Metformin
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Total 8616 results found since Jan 2013.
Metformin inhibits proliferation and promotes apoptosis of HER-2 positive breast cancer cells possibly through the Hippo-YAP pathway
CONCLUSION: Metformin can inhibit proliferation and promote apoptosis and epithelal-mesenchymal transition of HER-2 positive breast cancer cells possibly by that inhibing YAP and TAZ expression and their nuclear localization.PMID:35673919 | PMC:PMC9178637 | DOI:10.12122/j.issn.1673-4254.2022.05.16
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: Y Xu T Xu Y Xiong J Huang Source Type: research
Dihydromyricetin improves cardiac insufficiency by inhibiting HMGB1 in diabetic rats
CONCLUSION: DHM treatment can improve cardiac function in diabetic rats possibly by down-regulation of HMGB1 and phospho-NF-κB p65 expressions in the myocardium.PMID:35673906 | PMC:PMC9178629 | DOI:10.12122/j.issn.1673-4254.2022.05.03
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: S Liu Q Liu Q Peng Y Zhang J Wang Source Type: research
Fucoxanthin regulates Nrf2/Keap1 signaling to alleviate myocardial hypertrophy in diabetic rats
CONCLUSION: Fucoxanthin possesses strong inhibitory activities against diabetic cardiomyocyte hypertrophy and myocardial fibrosis and is capable of up-regulating Nrf2 signaling to promote the expression of its downstream antioxidant proteins SOD1 and HO-1 to reduce the level of ROS.PMID:35673921 | PMC:PMC9178635 | DOI:10.12122/j.issn.1673-4254.2022.05.18
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: D Zheng L Chen Q Wei Z Zhu Z Liu L Jin G Yang X Xie Source Type: research
Metformin inhibits proliferation and promotes apoptosis of HER-2 positive breast cancer cells possibly through the Hippo-YAP pathway
CONCLUSION: Metformin can inhibit proliferation and promote apoptosis and epithelal-mesenchymal transition of HER-2 positive breast cancer cells possibly by that inhibing YAP and TAZ expression and their nuclear localization.PMID:35673919 | PMC:PMC9178637 | DOI:10.12122/j.issn.1673-4254.2022.05.16
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: Y Xu T Xu Y Xiong J Huang Source Type: research
Dihydromyricetin improves cardiac insufficiency by inhibiting HMGB1 in diabetic rats
CONCLUSION: DHM treatment can improve cardiac function in diabetic rats possibly by down-regulation of HMGB1 and phospho-NF-κB p65 expressions in the myocardium.PMID:35673906 | PMC:PMC9178629 | DOI:10.12122/j.issn.1673-4254.2022.05.03
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: S Liu Q Liu Q Peng Y Zhang J Wang Source Type: research
Fucoxanthin regulates Nrf2/Keap1 signaling to alleviate myocardial hypertrophy in diabetic rats
CONCLUSION: Fucoxanthin possesses strong inhibitory activities against diabetic cardiomyocyte hypertrophy and myocardial fibrosis and is capable of up-regulating Nrf2 signaling to promote the expression of its downstream antioxidant proteins SOD1 and HO-1 to reduce the level of ROS.PMID:35673921 | PMC:PMC9178635 | DOI:10.12122/j.issn.1673-4254.2022.05.18
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: D Zheng L Chen Q Wei Z Zhu Z Liu L Jin G Yang X Xie Source Type: research
Metformin inhibits proliferation and promotes apoptosis of HER-2 positive breast cancer cells possibly through the Hippo-YAP pathway
CONCLUSION: Metformin can inhibit proliferation and promote apoptosis and epithelal-mesenchymal transition of HER-2 positive breast cancer cells possibly by that inhibing YAP and TAZ expression and their nuclear localization.PMID:35673919 | PMC:PMC9178637 | DOI:10.12122/j.issn.1673-4254.2022.05.16
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: Y Xu T Xu Y Xiong J Huang Source Type: research
Dihydromyricetin improves cardiac insufficiency by inhibiting HMGB1 in diabetic rats
CONCLUSION: DHM treatment can improve cardiac function in diabetic rats possibly by down-regulation of HMGB1 and phospho-NF-κB p65 expressions in the myocardium.PMID:35673906 | PMC:PMC9178629 | DOI:10.12122/j.issn.1673-4254.2022.05.03
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: S Liu Q Liu Q Peng Y Zhang J Wang Source Type: research
Fucoxanthin regulates Nrf2/Keap1 signaling to alleviate myocardial hypertrophy in diabetic rats
CONCLUSION: Fucoxanthin possesses strong inhibitory activities against diabetic cardiomyocyte hypertrophy and myocardial fibrosis and is capable of up-regulating Nrf2 signaling to promote the expression of its downstream antioxidant proteins SOD1 and HO-1 to reduce the level of ROS.PMID:35673921 | PMC:PMC9178635 | DOI:10.12122/j.issn.1673-4254.2022.05.18
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: D Zheng L Chen Q Wei Z Zhu Z Liu L Jin G Yang X Xie Source Type: research
Metformin inhibits proliferation and promotes apoptosis of HER-2 positive breast cancer cells possibly through the Hippo-YAP pathway
CONCLUSION: Metformin can inhibit proliferation and promote apoptosis and epithelal-mesenchymal transition of HER-2 positive breast cancer cells possibly by that inhibing YAP and TAZ expression and their nuclear localization.PMID:35673919 | PMC:PMC9178637 | DOI:10.12122/j.issn.1673-4254.2022.05.16
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: Y Xu T Xu Y Xiong J Huang Source Type: research
Dihydromyricetin improves cardiac insufficiency by inhibiting HMGB1 in diabetic rats
CONCLUSION: DHM treatment can improve cardiac function in diabetic rats possibly by down-regulation of HMGB1 and phospho-NF-κB p65 expressions in the myocardium.PMID:35673906 | PMC:PMC9178629 | DOI:10.12122/j.issn.1673-4254.2022.05.03
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: S Liu Q Liu Q Peng Y Zhang J Wang Source Type: research
Fucoxanthin regulates Nrf2/Keap1 signaling to alleviate myocardial hypertrophy in diabetic rats
CONCLUSION: Fucoxanthin possesses strong inhibitory activities against diabetic cardiomyocyte hypertrophy and myocardial fibrosis and is capable of up-regulating Nrf2 signaling to promote the expression of its downstream antioxidant proteins SOD1 and HO-1 to reduce the level of ROS.PMID:35673921 | PMC:PMC9178635 | DOI:10.12122/j.issn.1673-4254.2022.05.18
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: D Zheng L Chen Q Wei Z Zhu Z Liu L Jin G Yang X Xie Source Type: research
Metformin inhibits proliferation and promotes apoptosis of HER-2 positive breast cancer cells possibly through the Hippo-YAP pathway
CONCLUSION: Metformin can inhibit proliferation and promote apoptosis and epithelal-mesenchymal transition of HER-2 positive breast cancer cells possibly by that inhibing YAP and TAZ expression and their nuclear localization.PMID:35673919 | PMC:PMC9178637 | DOI:10.12122/j.issn.1673-4254.2022.05.16
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: Y Xu T Xu Y Xiong J Huang Source Type: research
Dihydromyricetin improves cardiac insufficiency by inhibiting HMGB1 in diabetic rats
CONCLUSION: DHM treatment can improve cardiac function in diabetic rats possibly by down-regulation of HMGB1 and phospho-NF-κB p65 expressions in the myocardium.PMID:35673906 | PMC:PMC9178629 | DOI:10.12122/j.issn.1673-4254.2022.05.03
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: S Liu Q Liu Q Peng Y Zhang J Wang Source Type: research
Fucoxanthin regulates Nrf2/Keap1 signaling to alleviate myocardial hypertrophy in diabetic rats
CONCLUSION: Fucoxanthin possesses strong inhibitory activities against diabetic cardiomyocyte hypertrophy and myocardial fibrosis and is capable of up-regulating Nrf2 signaling to promote the expression of its downstream antioxidant proteins SOD1 and HO-1 to reduce the level of ROS.PMID:35673921 | PMC:PMC9178635 | DOI:10.12122/j.issn.1673-4254.2022.05.18
Source: Journal of Southern Medical University - June 8, 2022 Category: Universities & Medical Training Authors: D Zheng L Chen Q Wei Z Zhu Z Liu L Jin G Yang X Xie Source Type: research
