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Silver nanoparticles as a therapeutic agent in experimental cyclosporiasis.
In this study, silver nanoparticles were chemically synthesized to be evaluated for the first time for their anti-cyclospora effects in both immunocompetent and immunosuppressed experimental mice in comparison to the standard treatment. The effect of silver nanoparticles was assessed through studying stool oocyst load, oocyst viability, ultrastructural changes in oocysts, and estimation of serum gamma interferon. Toxic effect of the therapeutic agents was evaluated by measuring liver enzymes, urea and creatinine in mouse sera. Results showed that silver nanoparticles had promising anti-cyclospora potentials. The animals th...
Source: Experimental Parasitology - October 10, 2019 Category: Parasitology Authors: Gaafar MR, El-Zawawy LA, El-Temsahy MM, Shalaby TI, Hassan AY Tags: Exp Parasitol Source Type: research