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Case report: pandysautonomia
We present the case of a 25 year old previously healthy female who became unwell with abdominal pain and vomiting a day after taking part in a half marathon and was found to have a pseudo-obstruction requiring laparotomy. Post surgery she developed a dry mouth and urinary retention and was consistently tachycardic with labile blood pressure. She developed one episode of parotitis which resolved with antibiotics. Family history included relatives with Addison's disease, hypothyroidism and Raynaud's phenomenon. Neurological examination was normal. There were no other findings to suggest systemic autoimmune disease. Vasculiti...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Al-Ansari, A., Rickards, C., Thomas, L., Bain, S. Tags: Genetics, Immunology (including allergy), HIV/AIDS, Pain (neurology), Hypertension, Ophthalmology, Connective tissue disease, Musculoskeletal syndromes ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Neuromyelitis optica in hiv: a case report and literature review
We present a case and review the literature. A 49 year old lady of African descent with known HIV diagnosed in 2004 – compliant with her antiretroviral medication, Atripla – was admitted with a 3 week history of thoracic back pain, spreading paraesthesia and weakness involving both legs, and constipation. Examination revealed a spastic paraparesis, a sensory level at T3/4 on the right and reduced vibration sense to the iliac crests bilaterally. MRI spine revealed increased signal within the cord from T3–7 in keeping with a longitudinally extensive transverse myelitis. CSF was acellular with normal protein...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Appleton, J. P., Kenton, A. Tags: Neurogastroenterology, Immunology (including allergy), HIV/AIDS, Cranial nerves, Multiple sclerosis, Pain (neurology), Spinal cord, Ophthalmology ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Susac's syndrome: limitations of classical triad and fundoscopy in diagnosis. what can we learn from the tabloid literature?
Conclusions In cases of suspected Susac's syndrome, normally appearing retinal vessels on fundoscopy do not exclude retinal arteritis, especially when peripherally distributed, and a fluorescein angiogram should be requested. Although this has been recognised in the ophthalmic literature1, it is important for neurologists consider requesting the test despite normal fundoscopy. In addition, audiogram may be normal in form fruste presentations which may also include psychiatric features and migraine. Clinicians should not be dissuaded from considering Susac's if not all features of the classic triad are present.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Dani, K., Thomas, R. Tags: Immunology (including allergy), HIV/AIDS, Headache (including migraine), Multiple sclerosis, Pain (neurology), Ophthalmology, Radiology, Vascularitis, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College Source Type: research

Sensory neuronopathy; a case report and a review of the role of ganglion nerve biopsy in diagnosis
We present such a case in whom biopsy of the thoracic dorsal root ganglion resulted in identifying of continued inflammation despite normal haematological makers thereby altering subsequent management. A 54 year old telecommunications officer with a background of anterior uveitis presented with a 3 year history of progressive altered sensation of his right hand and a 2 month history of altered sensation of the right side of his face including oral mucosa. There was unilateral facial sensory loss to pin prick, right upper limb pseudoathetosis, hyperaesthesia of C5 to C8 and impaired proprioception to wrist. He was hyporefle...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Waddell, B., Farmer, S., Lunn, M., O'Riordan, J. I. Tags: Immunology (including allergy), HIV/AIDS, Drugs: CNS (not psychiatric), Ophthalmology, Radiology, Drugs: musculoskeletal and joint diseases, Surgical diagnostic tests Association of British Neurologists (ABN) joint meeting with the Royal College of Phys Source Type: research