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cbx2 is a functional target of the let-7 family in the gonad of Japanese flounder (Paralichthys olivaceus)
Comp Biochem Physiol B Biochem Mol Biol. 2022 Sep 22:110799. doi: 10.1016/j.cbpb.2022.110799. Online ahead of print.ABSTRACTAs a key member of the miRNA family, the role and target gene of the let-7 family in the gonad of Japanese flounder (Paralichthys olivaceus) is unclear. Chromobox homolog 2 (CBX2) is one of the core components of the polycomb group complex (PcG) and significantly influences gonadal development. The deletion of CBX2 can lead to sex reversal in mammals. Therefore, exploring the relationship between the let-7 family and cbx2 is crucial to clarify the role played by the let-7 family in the gonad of Japane...
Source: Comparative biochemistry and physiology. Part B, Biochemistry and molecular biology. - September 26, 2022 Category: Biochemistry Authors: Yahui Wu Yangyang Wang Yidong Xue Ningning Wu Jikui Wu Junling Zhang Source Type: research