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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Disability

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Total 286 results found since Jan 2013.

Prevalence of Stroke and Stroke Risk Factors in a South-Western Community of Nepal
The global burden of stroke in 2016 suggests that stroke is associated with approximately one million deaths and 22 million disability-adjusted life-years (DALYs) in South Asia, of which nearly 15,000 deaths and 330,000 DALYs occurred in Nepal.1 Stroke incurs a substantial economic burden to the national healthcare system2 and is often unaffordable to low-income families, particularly for those bearing out-of-pocket expenses for all the treatment costs.
Source: Journal of Stroke and Cerebrovascular Diseases - March 13, 2021 Category: Neurology Authors: Lekhjung Thapa, Shakti Shrestha, Rashmi Kandu, Mahesh Raj Ghimire, Sulochana Ghimire, Navin Kumar Chaudhary, Bishnu Pahari, Suman Bhattarai, Ghanshyam Kharel, Raju Paudel, Pankaj Jalan, Avinash Chandra, Subash Phuyal, Bhojraj Adhikari, Nirmal Aryal, Om P Source Type: research

Clinical Outcomes and Medical Costs of Hydration Therapy with Hydroxyethyl Starch (130/0.4) or Acute Single Infarction
Although a single infarction (SI) is typically predicted to have good outcomes, 20% –30% of SI patients experience secondary progressive motor deficits (PMD) occurring within a few days after SI onset, which often leads to severe disabilities.1 This disease type in lenticulostriate artery (LSA) is well known as branch atheromatous disease (BAD) in Japan.2 Neither evidence nor con sensus-based indications exist about how to prevent PMD2. Vascular risk factors, such as elevated haemoglobin A1c and blood pressure levels, as well as the characteristics of ischemic lesions, such as the size and location of the infarction, esp...
Source: Journal of Stroke and Cerebrovascular Diseases - March 10, 2021 Category: Neurology Authors: Ayaka Fujita, Masashi Matsuzaka, Norifumi Metoki, Joji Hagii, Hiroshi Shiroto, Manabu Iwata, Rina Tanaka, Eiichi Tsuda Source Type: research

Serum Levels of B-cell Lymphoma-2 Anti-Apoptotic Protein and Malignant Middle Cerebral Artery Infarction Mortality
In addition to many disabilities and deaths, ischemic stroke is also responsible for a great consumption of health resources.1 Apart from the primary brain injury due to vasculature obstruction, in ischemic stroke appears a secondary brain injury due to the activation of different physiopathological pathways (as apoptosis).2 –6 Apoptotic changes have been found in brain tissue samples of patients with ischemic stroke.7–11
Source: Journal of Stroke and Cerebrovascular Diseases - March 6, 2021 Category: Neurology Authors: Leonardo Lorente, Mar ía M. Martín, Agustín F. González-Rivero, Antonia Pérez-Cejas, Luis Ramos-Gómez, Jordi Solé-Violán, Juan J. Cáceres, Jacobo J. Villacampa-Jiménez, Alejandro Jiménez Source Type: research

Effect of Insurance Status on Outcomes of Acute Ischemic Stroke Patients Receiving Intra-Arterial Treatment: Results from the Paul Coverdell National Acute Stroke Program
Stroke continues to be a leading cause of death and disability in the United States. Rates of intra-arterial reperfusion treatments (IAT) for acute ischemic stroke (AIS) are increasing, and these treatments are associated with more favorable outcomes. We sought to examine the effect of insurance status on outcomes for AIS patients receiving IAT within a multistate stroke registry.
Source: Journal of Stroke and Cerebrovascular Diseases - March 3, 2021 Category: Neurology Authors: Ganesh Asaithambi, Xin Tong, Kamakshi Lakshminarayan, Sallyann M Coleman King, Mary G George Source Type: research

Decision-Making on Referral to Primary Care Physiotherapy After Inpatient Stroke Rehabilitation
Worldwide, stroke is a leading cause of death and disability.1 Although incidence rates are expected to increase over the next few decades, survival rates are expected to improve. Consequently, more stroke survivors will have to learn to live with the consequences. After acute stroke care or rehabilitation, returning home is one of the primary goals for stroke survivors.2 In the Netherlands, 65 % of stroke survivors return home immediately after acute hospital care.3 The remaining 35% continue inpatient rehabilitation in a rehabilitation center (RC) or geriatric rehabilitation center (GRC) before returning home.
Source: Journal of Stroke and Cerebrovascular Diseases - February 23, 2021 Category: Neurology Authors: Marieke Geerars, Roderick Wondergem, Martijn F. Pisters Source Type: research

Interactions of Cognitive and Physical Functions Associated with Toilet Independence in Stroke Patients
Every year, approximately 17 million people will experience their first stroke,1 which remains the second leading cause of death worldwide, with 5 ·5 million deaths in 2016.2 The mean global lifetime risk of stroke increased from 22.8% in 1990 to 24.9% in 2016.3 Also, stroke causes a greater range and complexity of disabilities compared to other chronic diseases.4,5 According to the World Health Organization, stroke causes permanent disabilit y to 5 million people each year.6 Following a stroke, there are various physical and cognitive impairments such as sensorimotor deficit of upper and lower limbs on the side contralat...
Source: Journal of Stroke and Cerebrovascular Diseases - February 5, 2021 Category: Neurology Authors: Takaaki Fujita, Yuichi Yamamoto, Kazuhiro Yamane, Yoko Ohira, Koji Otsuki, Toshimasa Sone, Kazuaki Iokawa Source Type: research

Factor XII Concentrations and Risk of Intracerebral Haemorrhage. A Prospective Case-Referent Study
Intracerebral haemorrhage (ICH) accounts for about 15% of all stroke in Sweden and is associated with high rates of death and disability.1,2 Biomarkers can be used in predicting disease risk as well as for disease diagnosis and prognosis estimation.3 A range of biomarkers have been studied in relationship to risk of ICH.4-7
Source: Journal of Stroke and Cerebrovascular Diseases - January 5, 2021 Category: Neurology Authors: Kristina Johansson, Lars Johansson, Torbj örn K. Nilsson, Marcus M. Lind Source Type: research

White Matter Acute Infarct Volume After Thrombectomy for Anterior Circulation Large Vessel Occlusion Stroke is Associated with Long Term Outcomes
Despite the proven efficacy of endovascular thrombectomy (EVT) for large vessel occlusion stroke, over half treated remain functionally disabled or die. Infarct topography may have implications for prognostication, patient selection, and the development of tissue-specific neuroprotective agents. We sought to quantify white matter injury in anterior circulation acute infarcts post-EVT to understand its significance and identify its determinants.
Source: Journal of Stroke and Cerebrovascular Diseases - December 30, 2020 Category: Neurology Authors: Robert W. Regenhardt, Mark R. Etherton, Alvin S. Das, Markus D. Schirmer, Joshua A. Hirsch, Christopher J. Stapleton, Aman B. Patel, Thabele M. Leslie-Mazwi, Natalia S. Rost Source Type: research

Electric Acupuncture Treatment Promotes Angiogenesis in Rats with Middle Cerebral Artery Occlusion Through EphB4/EphrinB2 Mediated Src/PI3K Signal Pathway
Cerebral infarction is one of the most common causes of disability and death worldwide. It is reported that electric acupuncture was able to improve the prognosis of cerebral infarction by promoting angiogenesis. However, the corresponding signal pathways of angiogenesis promotes by electric acupuncture treatment needs to be further explored.
Source: Journal of Stroke and Cerebrovascular Diseases - December 24, 2020 Category: Neurology Authors: Yuanhua Wu, Rong Hu, Xiuyan Zhong, Anbang Zhang, Bo Pang, Xiuqi Sun, Guangqi Zhu Source Type: research

Down-Regulation of miR-181a-5p Prevents Cerebral Ischemic Injury by Upregulating En2 and Activating Wnt/ β-catenin Pathway
Cerebral ischemic injury contributes to severe dysfunction of the brain, which triggers extremely high mortality and disability. The role of microRNA (miR)-181a-5p is documented in cerebral ischemic injury. Therefore, this study intended to further figure out the mechanism of miR-181a-5p in cerebral ischemic injury.
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2020 Category: Neurology Authors: Xiaoming Song, Yongming Xue, Hairui Cai Source Type: research

Determinants of Long-Term Health-Related Quality of Life in Young Ischemic Stroke Patients
The burden of stroke is multidimensional. The most commonly assessed stroke outcomes tend to be mortality and disability, which are physician reported measures. On the other hand, the health-related quality of life (HRQOL) measure evaluates stroke outcomes from the patients ’ perspective. It provides valuable information in that it rates physical, emotional, social, and other domains, and has repeatedly been associated with mortality.1,2
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2020 Category: Neurology Authors: Siim Schneider, Nele Taba, Minni Saapar, Riina Vibo, Janika K õrv Source Type: research

miR-221 Exerts Neuroprotective Effects in Ischemic Stroke by Inhibiting the Proinflammatory Response
Ischemic stroke is a common neurological disorder worldwide and is associated with a high probability of permanent disability.2 Unfortunately, our response to stroke is still extremely limited. Thus, since the exploration of novel and effective strategies is still the focus and is a well-studied topic in stroke treatment, recent research has focused on elucidating the molecular mechanisms of stroke, especially as those mechanisms pertain to novel treatment targets. Emerging experimental data have confirmed that microRNAs (miRNAs) are essential regulatory factors in ischemic stroke and other neurological diseases.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2020 Category: Neurology Authors: Yuan Shan, Jun Hu, Hua Lv, Xiaoli Cui, Wei Di Source Type: research

Stroke Research Disparity in Southeast Asia: Socioeconomic Factors, Healthcare Delivery, and Stroke Disease Burden
In recent decades, non-communicable diseases have outpaced communicable diseases as the leading causes of infirmity and loss of life and livelihood. One in four people over age 25 will experience a stroke in their lifetime.1 In low- to low-middle income countries (LMICs), stroke occurs at a younger age compared to high-income countries, contributing to a disproportionate amount of disability-adjusted life years (DALYs) lost and economic liabilities.2,3
Source: Journal of Stroke and Cerebrovascular Diseases - November 27, 2020 Category: Neurology Authors: Almira Doreen Abigail O. Apor, Gerald T. Pagaling, Adrian I. Espiritu, Roland Dominic G. Jamora Source Type: research

Treatment Approaches and Outcomes for Acute Anterior Circulation Stroke Patients with Tandem Lesions
Endovascular thrombectomy (EVT) has revolutionized stroke care for large vessel occlusions (LVOs). However, over half treated remain functionally disabled or die. Patients with tandem lesions, or severe stenosis/occlusion of the cervical internal carotid artery (ICA) with intracranial LVO, may have technical EVT challenges and worse outcomes. We sought to compare treatments and outcomes for patients with anterior circulation tandem lesions versus isolated LVOs.
Source: Journal of Stroke and Cerebrovascular Diseases - November 26, 2020 Category: Neurology Authors: Neal M. Nolan, Robert W. Regenhardt, Matthew J. Koch, Scott B. Raymond, Christopher J. Stapleton, James D. Rabinov, Scott B. Silverman, Thabele M. Leslie-Mazwi, Aman B. Patel Source Type: research

Significance of Cycle Ergometer as a Measure of Peak Aerobic Capacity in the Disabled
To compare different physiological responses between treadmill and cycle ergometer in stroke patients in regard to community ambulation, and to determine strong predictors of equipment-dependent VO2peak and its related factors among physical fitness parameters and finally to establish the significance of cycle ergometer as a measure of VO2peak in the disabled according to gait function.
Source: Journal of Stroke and Cerebrovascular Diseases - November 26, 2020 Category: Neurology Authors: Ho Min Yoon, Eun Young Han, Seung-Jae Joo Source Type: research