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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Disability
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Total 286 results found since Jan 2013.
Association Between Dispatch Complaint and Critical Prehospital Time Intervals in Suspected Stroke 911 Activations in the National Emergency Medical Services Information System, 2012 –2016
Stroke, one of the leading causes of death and disability in the United States (US), is a time sensitive emergency.1 Receiving timely treatment is associated with increased survival and better outcomes.2 –5 For every minute that treatment is delayed, a patient with stroke may lose an estimated 1.9 million neurons, leading to irreversible brain tissue damage long term disability, or death.6 Several studies have demonstrated that treatment with intravenous recombinant tissue-type plasminogen activat or (IV alteplase) can positively affect clinical outcomes when administered within a critical timeframe after ischemic stroke symptom onset.
Source: Journal of Stroke and Cerebrovascular Diseases - December 24, 2021 Category: Neurology Authors: Amena Y. Abbas, Erika C. Odom, Isaac Nwaise Source Type: research
Histological Analysis of Carotid Plaques: The Predictors of Stroke Risk
According to the Global Health Estimate in 2016, stroke is the second most common cause of death worldwide. It is also the leading cause of long-term adult disability.1 Prevention and proper treatment of stroke are of utmost importance, having not only economic effects but social and health effects as well. Besides heart diseases, carotid artery stenosis is a frequent cause of ischemic stroke.1
Source: Journal of Stroke and Cerebrovascular Diseases - December 23, 2021 Category: Neurology Authors: Norbert Svoboda, Richard Vold řich, Václav Mandys, Tomas Hrbáč, Petra Kešnerová, Martin Roubec, David Školoudík, David Netuka Source Type: research
Development and psychometric evaluation of a questionnaire for assessing self-management behaviors in stroke survivors
Stroke is a leading cause of global death and disability.1 Survivors ’ recovery journey after stroke involves rehabilitation in three domains, namely physical, psychological and social.2 However, this journey can be chronic, complex and demanding even for survivors of a mild stroke due to multiple interrelated impacts on their physical and psychosocial well-being. Furthermore, it can be complicated by survivors’ age-related changes and a decreasing level of support from healthcare professionals and family members as they transition to home.
Source: Journal of Stroke and Cerebrovascular Diseases - February 16, 2022 Category: Neurology Authors: Suzanne Hoi Shan LO, Janita Pak Chun CHAU, Kai Chow CHOI Source Type: research
Global Metabolomic Profiling Reveals Disrupted Lipid and Amino Acid Metabolism Between the Acute and Chronic Stages of Ischemic Stroke
Stroke is a major cause of serious disability in the United States. Previous studies found multiple associations of serum metabolites with acute ischemic stroke (AIS) compared to controls, but few of them evaluated metabolome in a longitudinal fashion. Therefore, we compared the metabolome of the acute and chronic stages of ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2022 Category: Neurology Authors: Evgeny V. Sidorov, Chao Xu, Jonathan Garcia-Ramiu, Apple Blair, Jorge Ortiz-Garcia, David Gordon, Juliane Chainakul, Dharambir K. Sanghera Source Type: research
Psychological Burden in Stroke Survivors and Caregivers Dyads at the Rehabilitation Center of Kinshasa (Democratic Republic of Congo): A Cross-Sectional Study
This study aimed to assess the burden of depression and anxiety and covariates as well as its association with functional disability level among stroke survivors and caregivers dyads.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2022 Category: Neurology Authors: Germain Manzekele Bin Kitoko, Bives Mutume Nzanzu Vivalya, Martial Mumbere Vagheni, Thierry Matonda Ma Nzuzi, Sam Mampunza Lusambulu, Gilbert Mananga Lelo, Magloire Nkosi Mpembi, Samuel Mampunza Ma Miezi Source Type: research
Associations Between Fatigue and Disability, Depression, Health-Related Hardiness and Quality of Life in People with Stroke
Stroke is a common cause of mortality and morbidity which affects approximately 17 million people globally each year. Common symptoms associated with stroke are physical disabilities, impaired cognitive functions, depression, and fatigue, all of which can significantly impact health-related quality of life (HRQoL). To date, no research has explored the inter-relationship among fatigue, disability, depression, health-related hardiness, and quality of life in stroke survivors.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2022 Category: Neurology Authors: David Sibbritt, Jessica Bayes, Wenbo Peng, Jane Maguire, Jon Adams Source Type: research
Outcome of a Real-World Cohort of Patients Subjected to Endovascular Treatment for Acute Ischemic Stroke
Ischemic stroke is a leading cause of death and disability worldwide. For patients with large vessel occlusion stroke, endovascular treatment is now the most effective treatment. We aimed to assess the outcome of patients undergoing endovascular treatment for large vessel occlusion stroke in a real-world setting, comparing our results with data from randomized clinical trials, and recognizing the factors associated with prognosis.
Source: Journal of Stroke and Cerebrovascular Diseases - April 25, 2022 Category: Neurology Authors: Giuseppe Scopelliti, Guglielmo Pero, Antonio Macera, Luca Quilici, Amedeo Cervo, Giulia Platania, Carlo Sebastiano Tadeo, Alessandro Cesare Prelle, Francesco Muscia, Maria Grazia Riggio, Angelo Zilioli, Elio Clemente Agostoni, Mariangela Piano, Leonardo P Source Type: research
Early Hyperchloremia and Outcomes After Acute Ischemic Stroke
There may be a potential relationship between hyperchloremia and death or disability after ischemic stroke given the association between hyperchloremia and acute kidney injury (AKI)1,2 and increased risk of death or disability with AKI.3 –5 Huang et al.6 reported that approximately 18% of patients with stroke have new onset hyperchloremia (≥ 110 mmol/L) within 72 h of admission which was associated with death or disability at 6 months. However, the association was no longer significant after adjusting for age and National In stitutes of Health stroke scale (NIHSS) scores.
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2022 Category: Neurology Authors: Adnan I. Qureshi, Wei Huang, Francisco E. Gomez, Kunal Malhotra, Niraj Arora, Premkumar N. Chandrasekaran, Farhan Siddiq, Brandi R. French, Camilo R. Gomez, Jose I. Suarez Source Type: research
Functional Recovery in Patients with Acute Stroke and Pre-Existing Disability: A Natural History Study
One million strokes occur in the United States every year, with as many as 1 in 3 occurring among patients with a pre-existing disability.1,2 Though they are a significant portion of the stroke population, such patients are often excluded from interventional trials.3-5 As a result, acute ischemic stroke patients with pre-morbid disability are often omitted from clinical practice treatment guidelines, such as for mechanical thrombectomy (MT). In the latest American Heart Association (AHA) guidelines, MT is only indicated for patients with no pre-stroke disability, as defined by a modified Rankin scale (mRS) score of 0-1.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2022 Category: Neurology Authors: Nicholas Vigilante, Scott Kamen, Ryan Shannon, Lauren Thau, Miriam Butler, Solomon Oak, Linda Zhang, Taryn Hester, Jesse M. Thon, James E. Siegler Source Type: research
Involvement of T-bet and GATA3 transcription factors in Mesenchymal stem cells and royal jelly combination treatment in brain stroke
Stroke as a common non-communicable disease can manifest itself as ischemic (87%) and hemorrhagic.1 However, the viable cells surrounding the infarct core have been shown to be at risk for infarct and apoptosis. Some therapeutic approaches are trying to improve neuronal recovery in the region and reduce post-stroke disability.2,3 Currently, to dissolve the clot and rescue the surrounding cells in the ischemic condition, tissue plasminogen activator (tPA) is administrated within the first three hours of the onset of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 24, 2022 Category: Neurology Authors: Mohammad Kazemi Arababadi, Mohammad Reza Rahmani, Fatemeh Asadi, Ahmad Shabanizadeh, Aliakbar Yousefi-Ahmadipour Source Type: research
Barriers to and facilitators for making emergency calls – a qualitative interview study of stroke patients and witnesses
Stroke is a leading cause of death and disability worldwide.1 Ischemic stroke (IS) accounts for 85 % of all stroke cases.2 Reperfusion therapy with intravenous thrombolysis (IVT)3,4 and endovascular thrombectomy are effective treatments of IS.5 However, treatment results are highly time dependent.6,7
Source: Journal of Stroke and Cerebrovascular Diseases - August 26, 2022 Category: Neurology Authors: Ida Bakke, Christian Georg Lund, Maria Carlsson, Rolf Salvesen, Britt Normann Source Type: research
Moving from traditional to more advanced treatments in stroke care is cost-effective: A case study from Greece
Ischemic stroke (IS) is one of the leading causes of mortality and disability,1, 2 with the economic burden of post-stroke care being substantial.1, 2 After incidence of IS, the following effective treatments have been found to significantly improve survival and quality of life: (a) treatment in specialized centres (Stroke Units; SU), (b) use of intravenous thrombolytic therapy (IVT), (c) use of endovascular thrombectomy (EVT) for patients with large vessel occlusions (LVO) and (d) rehabilitation.
Source: Journal of Stroke and Cerebrovascular Diseases - September 10, 2022 Category: Neurology Authors: Konstantinos Dimitriadis, Ilias Kyriopoulos, Georgios Tsivgoulis, Konstantinos Vemmos, Wolfgang G. Kunz, Elias Mossialos Source Type: research
Evaluating the performance of the PRISMA-7 frailty criteria for predicting disability and death after acute ischemic stroke
Stroke is the second cause of death and disability in the world, affecting close to 14 million people globally per year and being responsible for around 120 million disability-adjusted life years.1,2 More deaths occur worldwide because of stroke than AIDS, tuberculosis, and malaria combined.3 Therefore, being able to identify which individuals with stroke are at highest risk of poor function and mortality is critically important given the need for weighing the risks, costs, and benefits of interventions during various shared decision-making processes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 22, 2022 Category: Neurology Authors: Luana Aparecida Miranda, Gustavo Jos é Luvizutto, Blossom Christa Maree Stephan, Juli Thomaz de Souza, Taís Regina da Silva, Fernanda Cristina Winckler, Natalia Cristina Ferreira, Leticia Claudia de Oliveira Antunes, Pedro Augusto Cândido Bessornia, Si Source Type: research
Factors related to unfavorable outcome in minor ischemic stroke
Stroke recurrence and disability are important challenges to overcome in patients with minor ischemic stroke. The aim of our study was to determine the factors associated with unfavorable outcomes in patients with minor ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 11, 2023 Category: Neurology Authors: Mai Duy Ton, Dao Viet Phuong, Vu Thi Thom, Nguyen Tien Dung, Pham Quang Tho, Le Duc Thuan, Thanh N. Nguyen Source Type: research
Bone marrow mesenchymal stem cell-derived exosomal miR-193b-5p reduces pyroptosis after ischemic stroke by targeting AIM2
Ischemic stroke is a frequently occurring cerebrovascular disease (CVD) linked to high mortality, disability, and incidence rates, and the second factor causing global mortality41,3. There are two common sources of embolism in ischamic strokes: large artery atherosclerosis and small artery atherosclerosis. Ischemic stroke can be treated clinically with thrombolytic therapy4. Although ischemic stroke is treatable, post-cerebral ischemia blood reperfusion frequently induces inflammation, oxidative stress (OS) or additional unfavorable events that may exacerbate brain injury20,24.
Source: Journal of Stroke and Cerebrovascular Diseases - June 30, 2023 Category: Neurology Authors: Yingju Wang, Hongping Chen, Xuehui Fan, Chen Xu, Meng Li, Hongxue Sun, Jihe Song, Feihong Jia, Wan Wei, Fangchao Jiang, Guozhong Li, Di Zhong Source Type: research
