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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Disability
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Total 286 results found since Jan 2013.
Factors affecting self-reported bleeding acceptance in acute ischemic stroke survivors on various types of antithrombotic therapy
Stroke causes long-term serious disability with global prevalence of 101 million people in 2019.1 Antithrombotic therapy is recommended for stroke secondary prevention depending on the acute ischemic stroke (AIS) subtype.2 One of the major causes of non-cardioembolic AIS is intracranial atherosclerosis, which requires single antiplatelet therapy (SAPT), mostly with aspirin.3,4 Dual antiplatelet therapy (DAPT) may reduce the risk of non-cardioembolic stroke by 29% in AIS attributable to severe intracranial stenosis when used for a limited period of time.
Source: Journal of Stroke and Cerebrovascular Diseases - November 16, 2022 Category: Neurology Authors: Gabriela Rusin, Jadwiga Kubica, Krzysztof Piotr Malinowski, Agnieszka S łowik, Anetta Undas Source Type: research
Effects of virtual reality-based telerehabilitation for stroke patients: A systematic review and meta-analysis of randomized controlled trials
Stroke is a severe neurological disorder that occurs in nearly 800,000 people and kills more than 140,000 people per year in the United States.1 The cost of stroke is projected to rise to $231 billion by the year 2030.2 Moreover, stroke is the leading cause of serious long-term disability.1 These stroke survivors suffer from a variety of impairments, including motor, sensory, speech, cognition, and psychosocial aspects. Those impairments affect their independence to perform daily activities, and furtherly hamper their participation and quality of life.
Source: Journal of Stroke and Cerebrovascular Diseases - December 29, 2022 Category: Neurology Authors: Jie Hao, Yuqi Pu, Zhen Chen, Ka-Chun Siu Source Type: research
Determinants of stroke mortality among west africans: findings from the siren study
Stroke is one of the leading causes of death and disability in low-and-medium-income countries, but the pattern and determinants of stroke fatality are yet to be clearly understood among Africans. We assessed the determinants of stroke mortality among adults from 15 sites in Ghana and Nigeria in the Stroke Investigative Research and Educational Network (SIREN) study in West Africa.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2023 Category: Neurology Authors: Akinkunmi Paul Okekunle, Fred Stephen Sarfo, Onoja Matthew Akpa, Osahon Jeffery Asowata, Joshua Akinyemi, Adekunle Fakunle, Godwin Ogbole, Albert Akpalu, Kolawole Wahab, Reginald Obiako, Morenikeji Komolafe, Godwin Osaigbovo, Lukman Owolabi, Rufus Akinyem Source Type: research
RNA binding protein RPS3 mediates microglial polarization by activating NLRP3 inflammasome via SIRT1 in ischemic stroke
Stroke remains the leading cause of death and permanent disability worldwide and ischemic stroke represents 80% of all cases, which brings extremely serious consequences to the family and society.1 Ischemic stroke refers to the general term of cerebral blood supply artery stenosis or occlusion leading to cerebral blood circulation disorder, insufficient blood supply and brain tissue necrosis.2 Cerebral ischemic stroke occurs in middle-aged and elderly people, and arteriosclerosis and hypertension are the main pathogenic factors.
Source: Journal of Stroke and Cerebrovascular Diseases - April 21, 2023 Category: Neurology Authors: Dimi Zhou, Lin Chen, Yuzheng Wang, Lu Gan, Mei Yuan, Lei Zhang, Fenfang Chen Source Type: research
Hospital Discharge and Readmissions Before and During the COVID-19 Pandemic for California Acute Stroke Inpatients
Stroke is a leading cause of death and disability in the United States, with approximately 795,000 new strokes occurring annually, including acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH).1 The Coronavirus Disease 2019 (COVID-19) pandemic has impacted all levels of care for stroke patients, such as delays in initial presentation, reduction in acute therapies, limitations of in-patient resources, delays or lack of initiation of secondary stroke prevention therapy, and limitations in rehabilitation services after hospital discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2023 Category: Neurology Authors: George P. Albert, Daryl C. McHugh, Debra E. Roberts, Adam G. Kelly, Remi Okwechime, Robert G. Holloway, Benjamin P. George Source Type: research
Risk assessment of mechanic thrombectomy on post-stroke seizures: a systematical review and meta-analysis
Acute ischemic stroke is a leading cause of disability, with over a third of survivors developing new post-stroke disabilities around the world.1 Many post-stroke patients have a significant higher risk of developing post-stroke seizures of which the incidence has also been increasing over the past decades.2 Cerebrovascular disease is the leading cause of seizures in adults over 60-year-old, which has been shown to account for nearly 50% of newly diagnosed epilepsy in this age group.3
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2023 Category: Neurology Authors: Wen Jiang, Xiaoyan Zhu, Chunyan Lei, Guoliang Jiang, Linming Zhang, Song Mei, Lianmei Zhong Source Type: research
Association of underlying untreated cardiovascular risk factors with mortality and functional outcome in ischaemic stroke patients
Stroke is the third leading cause of death after ischaemic heart disease (IHD) and pneumonia in Malaysia.1 Aziz et al. reported that Malaysia's prevalence of ischaemic stroke had increased from 42.8 to 118.7 in 100,000 from 2010 to 2014. The report showed that 8-11% of ischaemic stroke patients died within 30 days while 56-61% survived with significant disability in Malaysia.2 Our previous study showed that patients with ischaemic stroke in Malaysia were younger, but the mortality rate was higher than in other countries.
Source: Journal of Stroke and Cerebrovascular Diseases - July 19, 2023 Category: Neurology Authors: Teck Long King, Lee Len Tiong, Zariah Abdul Aziz, Wan Chung Law Source Type: research
Diversity of Stroke Presentation in CADASIL: Study from Patients Harboring the Predominant NOTCH3 Mutation R544C
This study investigated the clinical stroke presentation and cranial magnetic resonance imaging (MRI) findings in a group of patients with CADASIL. We reviewed the clinical stroke presentation and brain MRI findings in 73 consecutive Korean patients aged>18 years diagnosed with CADASIL between May 2004 and April 2009. Brain MRI images were also scored for lacunar infarction and cerebral microbleeds. Intracranial atherosclerosis (ICAS) was assessed by magnetic resonance angiography. Disability was measured with the modified Rankin scale (mRS) and classified as good (mRS score 0-2) or poor (mRS score 3-5). In this study, 65 ...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2011 Category: Neurology Authors: Jay Chol Choi, Sook-Keun Song, Jung Seok Lee, Sa-Yoon Kang, Ji-Hoon Kang Tags: Original Articles Source Type: research
Factors Associated with SF-12 Physical and Mental Health Quality of Life Scores in Adults with Stroke
Conclusions: Sociodemographic, comorbidity, and stroke-related disability factors have differential effect on physical and mental aspects of QOL in poststroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - October 17, 2011 Category: Neurology Authors: Charles Ellis, Anouk L. Grubaugh, Leonard E. Egede Tags: Original Articles Source Type: research
Factors Related to Performance-Based Mobility and Self-reported Physical Activity in Individuals 1-3 Years after Stroke: A Cross-sectional Cohort Study
The objective of this study was to relate these outcomes to physical, psychological, and demographic determinants.Methods: In this cross-sectional cohort study, a consecutive sample of 195 community-living individuals, 65-85 years of age (74 ± 5 years, 71% men) with a previous stroke was included. Exclusion criteria were severe aphasia and severe cognitive dysfunction. Mobility status was measured by the Short Physical Performance Battery (SPPB, 0-12 points), and physical activity was measured using the Physical Activity Scale for the Elderly (PASE).Results: Mobility (SPPB, median 9 points) and level of physical activ...
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2013 Category: Neurology Authors: Birgit Vahlberg, Tommy Cederholm, Birgitta Lindmark, Lena Zetterberg, Karin Hellström Tags: Original Articles Source Type: research
Recurrent Ischemic Stroke in an Adult with Cystinosis: A Clinical–Pathological Case
A 32-year-old woman with infantile nephropathic cystinosis presented with cystinosis and recurrent ischemic stroke. The neuropathological description demonstrates that recurrent stroke was caused by intracranial stenosis and showed evidence of cystinosis brain involvement. There are few reports of cerebrovascular disease in patients with longstanding nephropathic cystinosis. This case reinforces that cerebrovascular disease can be a cause of neurological impairment and disability in patients with longstanding nephropathic cystinosis, with implications on primary stroke prevention strategies in these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - July 17, 2013 Category: Neurology Authors: Dulce Neutel, Ruth Geraldes, Pedro Pereira, António Gomes da Costa, José Pimentel, Teresa Pinho e Melo Tags: Case Reports Source Type: research
Deleterious Effect of Smoking on Ischemic Stroke Outcomes: Implications for the Role of Chronic Inflammation on Atherosclerotic Plaque Pathogenesis
I have read, with great interest, a recently published article in the Journal of Stroke and Cerebrovascular Diseases by Edjoc et al titled “The prognostic effect of cigarette smoking on stroke severity, disability, length of stay in hospital, and mortality in a cohort with cerebrovascular disease.” The authors performed a retrospective analysis of the Registry of the Canadian Stroke Network to identify the effect of smoking on cerebrovascular disease outcomes. More than 20,000 patients from the registry, spanning an approximately 5-year time interval, were included in the study. Multivariate logistic regression analys...
Source: Journal of Stroke and Cerebrovascular Diseases - March 1, 2014 Category: Neurology Authors: Dale Ding Tags: Letters to the Editor Source Type: research
High Blood Pressure on Admission in Relation to Poor Outcome in Acute Ischemic Stroke with Intracranial Atherosclerotic Stenosis or Occlusion
Conclusions: Higher BP on admission was associated with an increased risk of death or disability in patients with symptomatic intracranial artery stenosis or occlusion. It is reasonable that further studies on the effects of BP lowering in acute stroke include these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2014 Category: Neurology Authors: Zilong Hao, Ming Liu, Deren Wang, Bo Wu, Wendan Tao, Xueli Chang Tags: Original Articles Source Type: research
The Application of Cycling and Cycling Combined with Feedback in the Rehabilitation of Stroke Patients: A Review
Stroke is a leading cause of long-term disabilities, such as hemiparesis, inability to walk without assistance, and dependence of others in the activities of daily living. Motor function rehabilitation after stroke demands for methods oriented to the recovery of the walking capacity. Because of the similarities with walking, cycling leg exercise may present a solution to this problem. The aim of this article is to review the state of the art applications of cycling leg exercise as a (1) motor function rehabilitation method and an (2) aerobic training method for stroke patients as well as the commonly used (3) assessment tools.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2014 Category: Neurology Authors: David Barbosa, Cristina P. Santos, Maria Martins Tags: Review Article Source Type: research
Identification of Stroke Etiology May Contribute to Improve the Outcome in Dedicated Units
The purpose of our study is to investigate whether stroke unit (SU) care and the utilization of Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria may contribute to reduce death and disability in hospitalized patients after a first-ever ischemic stroke (IS).
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2015 Category: Neurology Authors: Lucio D'Anna, Gian L. Gigli, Giorgia Gregoraci, Giessica Canal, Federico Giopato, Francesco Janes, Anna Perelli, Valentina Russo, Barbara Zanchettin, Mariarosaria Valente Source Type: research
