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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Disability
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Total 286 results found since Jan 2013.
Nomogram for predicting delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage in the Chinese population
The incidence of stroke is high worldwide1 and is the leading cause of death in China presently.2,3 Subarachnoid hemorrhage caused by ruptured intracranial aneurysm is a subtype of severe stroke that occurs suddenly in seemingly healthy individuals with generally poor prognosis.4 Surgical clipping and endovascular coiling are effective treatment modalities for patients with aneurysmal subarachnoid hemorrhage (aSAH). Delayed cerebral ischemia (DCI) is a complication of aSAH, occurring in up to 30% of patients,5 and is an important cause of disability and death, often leading to deterioration of patients ’ condition or quality of life.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Haonan Liu, Qian Xu, Aimin Li Source Type: research
Combination of Scalp Acupuncture with Exercise Therapy Effectively Counteracts Ischemic Brain Injury in Rats
Stroke is one of the leading causes of death and disability worldwide. Scalp acupuncture and exercise therapy have been proven as two effective methods for the treatment of stroke. However, their combined action and mechanisms have not been fully elucidated. The present study aimed to investigate the protective effect of scalp acupuncture combined with exercise therapy on neurons in rats with ischemic brain injury.
Source: Journal of Stroke and Cerebrovascular Diseases - September 3, 2020 Category: Neurology Authors: Zhenjing Li, Xianzhong Meng, Min Ren, Minglu Shao Source Type: research
Hemicraniectomy for Dominant vs Nondominant Middle Cerebral Artery Infarction: A Systematic Review and Meta-Analysis
Decompressive hemicraniectomy decreases mortality and severe disability from space-occupying middle cerebral artery infarction in selected patients. However, attitudes towards hemicraniectomy for dominant-hemispheric stroke have been hesitant. This systematic review and meta-analysis examines the association of stroke laterality with outcome after hemicraniectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - September 15, 2021 Category: Neurology Authors: Silja R äty, Georgios Georgiopoulos, Karoliina Aarnio, Nicolas Martinez-Majander, Eberhard Uhl, George Ntaios, Daniel Strbian Source Type: research
Prevalence and Risk Factors of Silent Cerebral Microbleeds in Patients with Coronary Artery Disease
Coronary artery disease (CAD) and stroke are the two most common causes of death and disability worldwide, notably affecting aging populations.1 These cardiovascular disorders lead to impaired activity daily life and increase the risk of dementia.2,3 Brain magnetic resonance imaging (MRI) has excellent sensitivity in detecting ischemic lesions and can reveal asymptomatic, small, cerebral hemorrhages that are called cerebral microbleeds (CMBs).4 A systematic review reported that microbleeds were present on the MRIs of 5% of healthy adults, 34% of patients with ischemic stroke, and 60% of patients with nontraumatic intracerebral hemorrhage.
Source: Journal of Stroke and Cerebrovascular Diseases - November 22, 2021 Category: Neurology Authors: Ryo Yokoyama, Yumiko Kanzaki, Tomohiko Watanabe, Kenichiro Yamamura, Tsuyoshi Komori, Yoshihiro Takeda, Osamu Nakajima, Koichi Sohmiya, Masaaki Hoshiga Source Type: research
Effect of Primary Prophylactic Antiseizure Medication for Seizure Prevention Following Intracerebral Hemorrhage in the ERICH Study
Intracerebral hemorrhage (ICH) has the highest morbidity and mortality rate of any stroke subtype and clinicians often administer prophylactic antiseizure medications (ASMs) as a means of preventing post-stroke seizures, particularly following lobar ICH. However, evidence for ASM efficacy in preventing seizures and reducing disability is lacking given limited randomized trials. Herein, we report analysis from a large prospective observational study that evaluates the effect of primary prophylactic ASM administration on seizure occurrence and disability following ICH.
Source: Journal of Stroke and Cerebrovascular Diseases - October 26, 2021 Category: Neurology Authors: Krupa Savalia, Padmini Sekar, Charles J Moomaw, Sebastian Koch, Kevin N Sheth, Daniel Woo, Douglas Mayson, ERICH Investigators Source Type: research
Resveratrol Alleviates Ischemic Brain Injury by Inhibiting the Activation of Pro-Inflammatory Microglia Via the CD147/MMP-9 Pathway
This study was intended to investigate the mechanism of resveratrol (RES) regulating microglia activation through the CD147/matrix metalloproteinase-9 (MMP-9) pathway on ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 27, 2022 Category: Neurology Authors: Haifang Zhang, Wenjing Zhao Source Type: research
Modified Rankin scale assessment by telephone using a simple questionnaire
: The modified Rankin Scale (mRS) is widely used as a measure of post-stroke physical disability in clinical stroke trials; however, it is affected by inter-rater discrepancies. A Japanese version of the simplified mRS questionnaire (J-RASQ) has the potential to overcome the inter-rater discrepancies and might be feasible for clinical surveys. We aimed to determine the reliability of J-RASQ in a telephone survey administered by non-medical staff.
Source: Journal of Stroke and Cerebrovascular Diseases - August 30, 2022 Category: Neurology Authors: Kenichiro Yi, Makoto Nakajima, Tomoaki Ikeda, Mineko Yoshigai, Mitsuharu Ueda Source Type: research
Lower 25-hydroxyvitamin D is associated with severer white matter hyperintensity and cognitive function in patients with non-disabling ischemic cerebrovascular events
Vascular cognitive impairment (VCI) is the second most common type of cognitive impairment, referring to the entire spectrum of cognitive impairment contributed by cerebrovascular pathology1. Due to the progressively higher incidence of stroke and cerebrovascular diseases, VCI, including post-stroke cognitive impairment are the leading causes of disability epidemic worldwide2-3. White matter lesions, manifested as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI) scans, are one of the most common pathological characteristics of VCI4.
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2023 Category: Neurology Authors: Zhengsheng Gu, Xu Sun, Chenghao Wu, Binghan Li, Jingjing Chen, Weisen Wang, Xin Gao, Yuhao Tan, Bin Li, Ge Yin, Yawen Xu, Chenrui Song, Bingying Du, Xiaoying Bi Source Type: research
Long-term Improvement in Outcome After Intracerebral Hemorrhage in Patients Treated with Statins
Conclusions: Statin use is associated with improved long-term outcome at 12 months after ICH. This finding supports previous clinical studies that have shown the short-term benefits of statin therapy. In addition, this study correlates with animal studies supporting the possible long-term recovery benefits of statins.
Source: Journal of Stroke and Cerebrovascular Diseases - July 17, 2013 Category: Neurology Authors: Jonathan Winkler, John Paul Shoup, Alexandra Czap, Ilene Staff, Gilbert Fortunato, Louise D. McCullough, Lauren H. Sansing Tags: Original Articles Source Type: research
Nontraumatic Convexity Subarachnoid Hemorrhage: Different Etiologies and Outcomes
Conclusions: Significant ICA atherosclerotic stenosis was the most frequent cause of cSAH in our series, reinforcing that cSAH should prompt vascular imagiological evaluation including cervical vessels. Outcomes in cSAH seem to be related to etiology. Patients with undetermined etiology should be followed up because cSAH may be the first manifestation of CAA.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Ruth Geraldes, Paulo R. Sousa, Ana C. Fonseca, Filipa Falcão, Patrícia Canhão, Teresa Pinho e Melo Tags: Original Articles Source Type: research
Neurologic and Functional Long-term Outcome after Carotid Endarterectomy
Background: The aim of this research was to assess the neurologic status of patients a year after endarterectomy with the use of National Institutes of Health Stroke Scale (NIHSS) and the degree of disability using the modified Rankin Scale (mRS) and to examine the patients' subjective evaluation of their health.Methods: One hundred two patients with symptomatic internal carotid artery stenosis who underwent endarterectomy and attended a 1-year follow-up examination were enrolled in the study. The material comprised 72 (70.6%) men and 30 (29.4%) women. Before the surgery, the patients' neurologic status was assessed accord...
Source: Journal of Stroke and Cerebrovascular Diseases - July 15, 2013 Category: Neurology Authors: Piotr Kaźmierski, Mirosław Stelągowski, Anna Kasielska-Trojan, Katarzyna Bogusiak, Andrzej Glabinski Tags: Original Articles Source Type: research
Comparison of Sonothrombolysis Efficiencies of Different Ultrasound Systems
Stroke is a severe emergent cardiologic disease for death and permanent disability. Ultrasound exposure could noninvasively enhance the clot lysis of tissue plasminogen activator (tPA) with the presence of microbubbles (MBs). A variety of sonography systems are available in the market, and whether sonothrombolysis is only successful using specific devices is unknown.
Source: Journal of Stroke and Cerebrovascular Diseases - September 17, 2014 Category: Neurology Authors: Yufeng Zhou, Rajan Ramaswami Source Type: research
International Comparison of Poststroke Resource Use: A Longitudinal Analysis in Europe
Long-term costs often represent a large proportion of the total costs induced by stroke, but data on long-term poststroke resource use are sparse, especially regarding the trajectory of costs by severity. We used a multinational longitudinal survey to estimate patterns of poststroke resource use by degree of functional disability and to compare resource use between regions.
Source: Journal of Stroke and Cerebrovascular Diseases - August 12, 2015 Category: Neurology Authors: David B. Matchar, Marcel Bilger, Young K. Do, Kirsten Eom Source Type: research
Epigallocatechin Gallate Extends the Therapeutic Window of Recombinant Tissue Plasminogen Activator Treatment in Ischemic Rats
Ischemic stroke is the leading cause of death and disability worldwide. To date, recombinant tissue plasminogen activator (rt-PA) remains the only safe and effective pharmaceutical treatment for brain ischemia, but delayed rt-PA administration leads to hyperperfusion, which severely limits its clinical efficacy.
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2016 Category: Neurology Authors: Yi-Ping You Source Type: research
Plasma D-dimer Level, the Promising Prognostic Biomarker for the Acute Cerebral Infarction Patients
Despite being an important cause of death and functional disability, acute cerebral infarction (ACI) lacks accurate and easy tools to predict the outcome of patients beyond clinical variables such as age and stroke severity.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2016 Category: Neurology Authors: Jing Wang, Ruizhuo Ning, Yuping Wang Source Type: research
