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Prevalence and risk factors of stroke in the elderly in Northern China: data from the National Stroke Screening Survey
AbstractBackgroundThe overall global burden of stroke is considerable and increasing. In China, stroke is the leading cause of death and disability.MethodsFor this study, we used data from the National Stroke Screening Survey in 2012 and the 2010 Chinese population from sixth National Census of Populations to calculate a standardized (by age, gender, and education) stroke prevalence. Prevalence, risk factors, and management of stroke were compared by gender, age, and site.FindingsThe standardized prevalence rate of survival stroke patients in study population aged 60 and older was 4.94% in total. Hypertension was the most ...
Source: Journal of Neurology - April 14, 2019 Category: Neurology Source Type: research

Association between marriage and outcomes in patients with acute ischemic stroke
ConclusionsMarital status was associated with all adverse stroke outcomes in patients with acute ischemic stroke, especially in those with middle-school education.
Source: Journal of Neurology - February 20, 2018 Category: Neurology Source Type: research

Time trends in stroke severity in the years 2005 to 2020: results from the Austrian Stroke Unit Registry
ConclusionDespite an aging population and generally increasing AF frequency, we observed a consistent trend towards less disabling strokes on admission.
Source: Journal of Neurology - March 21, 2022 Category: Neurology Source Type: research

Early apixaban therapy after ischemic stroke in patients with atrial fibrillation
ConclusionsSymptomatic HT rates are likely to be low in randomized trials of DOAC initiation post-stroke. Recurrent ischemic stroke may be the major clinical outcome. These data may be used as expected event rates when calculating sample size requirements for future safety/efficacy trials of early versus late DOAC initiation after AF-related stroke.
Source: Journal of Neurology - January 3, 2021 Category: Neurology Source Type: research

Sex-specific differences in presentations and determinants of outcomes after endovascular thrombectomy for large vessel occlusion stroke
ConclusionIn a real-world analysis of ELVO stroke patients treated with EVT, we found that despite advanced age and more pre-stroke disability, women have comparable reperfusion rates and functional outcomes compared to men. Sex-specific determinants of reperfusion and functional outcome were identified that require further study.
Source: Journal of Neurology - May 29, 2021 Category: Neurology Source Type: research

Stroke care in Italy at the time of the COVID-19 pandemic: a lesson to learn
AbstractFrom March to May 2020, the Italian health care system, as many others, was almost entirely devoted to the fight against the COVID-19 pandemic. In this context, a number of questions arose, from the increased stroke risk due to COVID-19 infection to the quality of stroke patient care. The overwhelming need of COVID-19 patient management made mandatory a complete re-organization of the stroke pathways: many health professionals were reallocated and a number of stroke units was turned into COVID-19 wards. As a result, acute stroke care suffered from a shortage of services and delays in time-dependent treatments and d...
Source: Journal of Neurology - June 21, 2021 Category: Neurology Source Type: research

Depressive symptoms in stroke patients treated and non-treated with intravenous thrombolytic therapy: a 1-year follow-up study
Conclusions(1) Thrombolysed and non-thrombolysed stroke survivors had similar frequency of depressive symptoms although the thrombolysed patients had more severe neurological deficits in the acute phase. It can be assumed that if thrombolysis had not been used, depressive symptoms would have been more frequent. (2) Lack of the rt-PA treatment was associated with three-time greater odds of screening for PSD at 3  months post-stroke, after adjustment for other PSD correlates. (3) Therefore, thrombolytic therapy seems to have a positive, but indirect, effect on patients’ mood, especially in the first months after stroke. (...
Source: Journal of Neurology - June 18, 2018 Category: Neurology Source Type: research

Premorbid frailty predicts short- and long-term outcomes of reperfusion treatment in acute stroke
DiscussionFrailty is an important predictor of efficacy of acute treatment of stroke beyond classical predictors of stroke outcomes. Larger longitudinal studies are, thus, warranted to evaluate the risk –benefit of reperfusion treatment in the growing elderly frail population.
Source: Journal of Neurology - January 17, 2022 Category: Neurology Source Type: research

The influence of previous infections and antichlamydia pneumoniae seropositivity on functional outcome in ischemic stroke patients: results from the IN2 study
Abstract Although a growing attention is being paid to acute ischemic stroke patients, the correlation between clinical outcome and infectious events in this population has been poorly investigated. 749 ischemic stroke (mean age 71 years old, males 56 %) patients were enrolled in this prospective case–control study by 11 Italian Stroke Units. Demographic data, vascular risk factors, previous infections and post-stroke infections (PSIs) were recorded. Blood samples were collected and the enzyme-linked immunoassay was chosen to measure Chlamydia pneumoniae IgG and IgA plasma antibodies (antibody titers were clas...
Source: Journal of Neurology - March 25, 2015 Category: Neurology Source Type: research

A review of mobile stroke units
AbstractPurpose of reviewMobile stroke units (MSUs) for prehospital treatment and management of patients with acute stroke have been developed more than a decade ago and is currently spreading worldwide. This review discusses the history of MSU and current operations and research.Recent findingsMultiple studies have shown that MSU can significantly reduce treatment time with a tenfold increase of patients treated within the first 60  min of symptom onset. Recent preliminary results from the Berlin Prehospital or Usual Delivery of Acute Stroke Care trial (B-PROUD) showed a positive shift in modified Rankin Scale (mRS) scor...
Source: Journal of Neurology - May 17, 2020 Category: Neurology Source Type: research

Platelet function/reactivity testing and prediction of risk of recurrent vascular events and outcomes after TIA or ischaemic stroke: systematic review and meta-analysis
DiscussionAntiplatelet –HTPR may predict risks of recurrent vascular events/outcomes in CVD patients. Given the heterogeneity between studies, further prospective, multi-centre studies are warranted.
Source: Journal of Neurology - June 8, 2020 Category: Neurology Source Type: research

Do patients with large vessel occlusion ischemic stroke harboring prestroke disability benefit from thrombectomy?
ConclusionOne of five with prestroke disability treated with thrombectomy for a LVO ischemic stroke returned to their prestroke functional level. However, compared to patients without prestroke disability, mortality at 3 months was higher.
Source: Journal of Neurology - May 13, 2020 Category: Neurology Source Type: research

Inter-hospital transfer for mechanical thrombectomy within the supraregional stroke network NEVAS
ConclusionWithin a telemedicine network stroke care can successfully be organized as only a minority of patients has to be transferred. Our data provide clinical evidence that all MT-eligible patients should be shipped with the fastest transportation modality as possible.
Source: Journal of Neurology - September 4, 2020 Category: Neurology Source Type: research

Stroke-unit care for stroke patients in China: the results from Bigdata Observatory platform for Stroke of China
ConclusionsAmong patients with stroke, admission to a designated SU was associated with modestly lower mortality at discharge, reduced probability of death, or being disabled at the end of follow-up.
Source: Journal of Neurology - April 22, 2021 Category: Neurology Source Type: research

Delirium on stroke units: a prospective, multicentric quality-improvement project
ConclusionsImplementation of delirium-management on SU is feasible and can be delivered to most patients, but with limited effects. Nursing interventions as first choice could be delivered to the majority of patients, and only the half required pharmacological treatments. Delirium-management may lead to reduced severity of POD but had only partial effects on duration of POD or length of stay. POD hampers rehabilitation, especially in patients with more severe stroke.RegistryDRKS, DRKS00021436. Registered 04/17/2020,www.drks.de/DRKS00021436.
Source: Journal of Neurology - February 14, 2022 Category: Neurology Source Type: research

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