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Renin-Angiotensin System Blocker Fetopathy
Chronic hypertension in pregnant women is associated with significant maternal and fetal morbidity and mortality, and is thought to complicate approximately 5% of the 4 million pregnancies in the US annually.1 Pregnant women with chronic hypertension are at risk for developing adverse complications, such as maternal preeclampsia, stroke, renal failure, and death.2 In addition, adverse fetal outcomes, such as intrauterine growth restriction, preterm birth, and death, are more likely among pregnant women with chronic hypertension than those without.
Source: The Journal of Pediatrics - August 5, 2015 Category: Pediatrics Authors: Janet D. Cragan, Bessie A. Young, Adolfo Correa Tags: Editorial Source Type: research

Neonatal Forearm Compartment Syndrome: Look for Cerebral Stroke
A male term newborn presented with a neonatal forearm compartment syndrome together with an ipsilateral cerebral stroke. Pregnancy and delivery were uneventful, except for oligohydramnios. His mother had celiac disease and hypothyroidism. Since birth, he showed a 4-cm bullous-ulcerated lesion on the left volar forearm and elbow fold (, A), with normal pulses, and an ipsilateral upper limb paresis with reduced motility, dropped wrist, no fingers extension, and grasping. Tendon reflexes were normal with Babinski sign bilaterally evident. Radiography showed a mild carpus asymmetry (left left). He had a residual scar on the fo...
Source: The Journal of Pediatrics - November 18, 2013 Category: Pediatrics Authors: Elena Pavlidis, Carlotta Spagnoli, Maddalena Duca, Francesca Ormitti, Cinzia Magnani, Francesco Pisani Tags: Insights and Images Source Type: research

Negative behaviors and events during pregnancy impact neonates’ birth characteristics
A growing body of literature identifies the negative impact of certain maternal behaviors (eg, smoking, substance abuse) on neonatal health (eg, preterm birth, low birth rate, smallness for gestational age). Smallness for gestational age is in turn associated with childhood developmental and behavioral problems, as well as excessive rates in adults of cardiovascular disease, stroke, non-insulin dependent diabetes mellitus, adiposity, and metabolic syndrome.
Source: The Journal of Pediatrics - August 1, 2013 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: research