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Efficacy of different statins for primary prevention of atrial fibrillation in male and female patients: A nationwide population-based cohort study
Atrial fibrillation (AF) is a common arrhythmia and is associated with increased cardiovascular morbidity and mortality . Meta-analysis of randomized controlled trials has showed that statin provides a protective effect against AF . However, different statins may have different levels of efficacy in AF prevention . Statin therapy exhibited different effects between genders in reducing mortality and stroke , and the data on a gender effect of statin in primary prevention of AF is limited. The purpose of this study was to determine the efficacy of different statins for primary prevention of AF in male and female patients.
Source: International Journal of Cardiology - May 29, 2013 Category: Cardiology Authors: Chen-Ying Hung, Yu-Cheng Hsieh, Kuo-Yang Wang, Jin-Long Huang, El-Wui Loh, Ching-Heng Lin, Tsu-Juey Wu Tags: Letters to the Editor Source Type: research

Left atrial size and function as predictors of new-onset of atrial fibrillation in patients with asymptomatic aortic stenosis: The simvastatin and ezetimibe in aortic stenosis study
Abstract: Background: Left atrial (LA) size and function change with chronically increased left ventricular (LV) filling pressures. It remains unclear whether these variations in LA parameters can predict new-onset atrial fibrillation (AF) in asymptomatic patients with aortic stenosis (AS).Methods: Data were obtained in asymptomatic patients with mild-to-moderate AS (2.5≤ transaortic Doppler velocity ≤4.0m/s), preserved LV ejection fraction (EF), no previous AF, and were enrolled in the Simvastatin and Ezetimibe in Aortic Stenosis study. Peak-aortic velocity, LAmax volume & LAmin volume were measured by echocardiograph...
Source: International Journal of Cardiology - February 18, 2013 Category: Cardiology Authors: Casper N. Bang, Morten Dalsgaard, Anders M. Greve, Lars Køber, Christa Gohlke-Baerwolf, Simon Ray, Anne B. Rossebø, Kenneth Egstrup, Kristian Wachtell Tags: Original Articles Source Type: research

Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction
Conclusions: AIS in patients with low EF is associated with older age, cardiac comorbidities, and more severe clinical presentation. Low EF can identify a subset of AIS patients at high risk of early and long-term functional disability and mortality.
Source: International Journal of Cardiology - November 23, 2012 Category: Cardiology Authors: Haralampos Milionis, Mohamed Faouzi, Maria Cordier, Suzette D'Ambrogio-Remillard, Ashraf Eskandari, Patrik Michel Tags: Original Articles Source Type: research

Prognostic importance of atrial fibrillation in asymptomatic aortic stenosis: The Simvastatin and Ezetimibe in Aortic Stenosis study
Conclusion: Rate of AF is moderate in asymptomatic AS. Longstanding but not episodic AF was, independently predictive of increased risk of heart failure and non-hemorrhagic stroke. New-onset AF was associated with cardiac decompensation.
Source: International Journal of Cardiology - October 13, 2011 Category: Cardiology Authors: Anders M. Greve, Eva Gerdts, Kurt Boman, Christa Gohlke-Baerwolf, Anne B. Rossebø, Christoph A. Nienaber, Simon Ray, Kenneth Egstrup, Terje R. Pedersen, Lars Køber, Ronnie Willenheimer, Kristian Wachtell Tags: Original Articles Source Type: research

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