• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Cerebral microbleeds and white matter hyperintensities in cardioembolic stroke patients due to atrial fibrillation: single-centre longitudinal study
Cerebral microbleeds (CMBs) are a potential predictor of future stroke risk with clinical relevance for antithrombotic treatments, especially in ischaemic stroke patients with atrial fibrillation. However, prospective data on CMBs and risk of stroke in this particular stroke population remain scarce. We therefore performed a single centre longitudinal study to investigate CMBs and white matter hyperintensities (WMH) and the risk of future stroke. Consecutive acute stroke patients, admitted during 2008 –2012 for presumed cardioembolic stroke due to non-valvular atrial fibrillation with available follow-up for the occurren...
Source: Journal of the Neurological Sciences - August 23, 2016 Category: Neurology Authors: Andreas Charidimou, Shigeru Inamura, Tatsufumi Nomura, Aya Kanno, Sang Nyon Kim, Toshio Imaizumi Tags: Clinical short communication Source Type: research

Early initiation of new oral anticoagulants in acute stroke and TIA patients with nonvalvular atrial fibrillation
Conclusions: The NOAC may be safe in acute stroke or TIA patients with NVAF. A large, prospective study is needed to confirm this.
Source: Journal of the Neurological Sciences - June 5, 2013 Category: Neurology Authors: Kensaku Shibazaki, Kazumi Kimura, Junya Aoki, Naoki Saji, Kenichiro Sakai Tags: Original Articles Source Type: research

Ischemic stroke in patients with atrial fibrillation receiving oral anticoagulation
Abstract: Background: Atrial fibrillation is the most common cause of embolic stroke associated to heart disease. Oral anticoagulation with vitamin K antagonists substantially reduces this risk.Aims: We assessed a group of patients with prior diagnosis of atrial fibrillation who sustained an ischemic stroke while receiving an adequate regime of oral anticoagulation.Methods: We evaluated consecutive patients with ischemic stroke and prior diagnosis of atrial fibrillation. We determined demographics, clinical characteristics, TOAST stroke subtypes, CHADS2 scores, and prior or concomitant use of oral anticoagulants.Results: W...
Source: Journal of the Neurological Sciences - September 20, 2013 Category: Neurology Authors: Virginia A. Pujol Lereis, Sebastian Ameriso, Guillermo P. Povedano, Sebastián F. Ameriso Tags: Original Articles Source Type: research

Reservations against new oral anticoagulants after stroke and cerebral bleeding
Abstract: Dabigatran, rivaroxaban, and apixaban are the new oral anticoagulants (NOAC) which have been investigated in patients with atrial fibrillation (AF) for primary and secondary prevention of stroke and thromboembolism. In these trials NOAC had a similar efficacy and safety profile compared to traditional vitamin-K-antagonists such as warfarin. We advise caution in the use of NOAC in patients with stroke or cerebral hemorrhage because of the following reasons:1) Patients with cerebral bleeding were excluded from the trials. 2) Stroke within 14days and severe stroke within 6months before screening were exclusion crite...
Source: Journal of the Neurological Sciences - April 29, 2013 Category: Neurology Authors: Claudia Stöllberger, Josef Finsterer Tags: Opinion Source Type: research

1.4 times increase in atrial fibrillation-related ischemic stroke and TIA over 12years in a stroke center
Prevalence of atrial fibrillation (AF) has quadrupled in the past 50years in the general population. However, there is uncertainty regarding prevalence of AF over time in ischemic stroke patients given the aging population and enhanced surveillance of AF. We aimed to explore the changing prevalence of AF as well as other risk factors, stroke subtypes, investigations and pre-stroke medications among ischemic stroke and transient ischemic attack (TIA) patients.
Source: Journal of the Neurological Sciences - May 11, 2017 Category: Neurology Authors: Qiong Yang, Leonid Churilov, Dongsheng Fan, Stephen Davis, Bernard Yan Source Type: research

Cardiac diastolic dysfunction predicts in-hospital mortality in acute ischemic stroke with atrial fibrillation
Conclusion: Diastolic dysfunction may be associated with in-hospital death in ischemic stroke patients with atrial fibrillation.Highlights:
Source: Journal of the Neurological Sciences - July 14, 2014 Category: Neurology Authors: Yohei Tateishi, Akira Tsujino, Jumpei Hamabe, Akira Tsuneto, Koji Maemura, Osamu Tasaki, Nobutaka Horie, Tsuyoshi Izumo, Kentaro Hayashi, Izumi Nagata Tags: Original Articles Source Type: research

Delayed elevation of plasma brain natriuretic peptide as a cue to diagnosis of atrial fibrillation in cryptogenic stroke: A case report
The cause of ischemic stroke is thought to be undetermined in around a quarter of patients [1]. Elevated plasma brain natriuretic peptide (BNP) levels in acute stroke patients are shown to be associated with paroxysmal atrial fibrillation (AF) [2]. It is widely recognized that elevated BNP levels on admission in cryptogenic stroke patients may be prognostic of AF. However, the relation between AF in cryptogenic stroke and elevated BNP levels on sub-acute or chronic phase have not been well established.
Source: Journal of the Neurological Sciences - August 8, 2017 Category: Neurology Authors: Kenichi Todo, Junko Ishii, Tomoyuki Kono, Taku Hoshi, Nobuo Kohara Tags: Letter to the Editor Source Type: research

Large vessel occlusion stroke due to dislodged aortic valve calcification revealed by imaging and histopathology
The search for aetiology in ischemic stroke represents one of the most challenging, costly and critical issues to set up adequate secondary prevention strategies. However, despite extensive clinical examinations, up to one-third of ischemic strokes have no established cause (cryptogenic stroke) [1]. In patients with two or more potential risk factors for stroke, final aetiology often cannot be properly defined. Moreover, even when a major risk factor is present, e.g., atrial fibrillation or atherosclerotic vessel stenosis, stroke aetiology often remains presumptive.
Source: Journal of the Neurological Sciences - November 6, 2019 Category: Neurology Authors: A. Genchi, G. Schwarz, A. Semerano, M. Callea, F. Sanvito, F. Simionato, P. Panni, F. Scomazzoni, C. Doglioni, G. Comi, A. Falini, F. Ancona, M. Filippi, L. Roveri, M. Bacigaluppi Tags: Letter to the Editor Source Type: research

A simple score for predicting paroxysmal atrial fibrillation in acute ischemic stroke
Conclusion: Our simple score can predict the presence of PAF during hospitalization in acute ischemic stroke.
Source: Journal of the Neurological Sciences - March 25, 2013 Category: Neurology Authors: Shuichi Fujii, Kensaku Shibazaki, Kazumi Kimura, Kenichiro Sakai, Junya Aoki Tags: Original Articles Source Type: research

CHADS2 score predicts functional outcome of stroke in patients with a history of coronary artery disease
Abstract: Background: The aim of this study was to evaluate the efficacy of the CHADS2 scoring system as a prognostic tool for stroke patients with a prior history of coronary artery disease (CAD).Methods: We enrolled 148 acute ischemic stroke patients (mean age, 74.2years; males, 77.0%) with a history of CAD. Pre-admission CHADS2 scores were calculated by assigning a single point for the presence of congestive heart failure, hypertension, age ≥75years, and diabetes; and assigning 2 points for a prior history of stroke or transient ischemic attack. Comparisons were made between patients with poor and good 3-month functio...
Source: Journal of the Neurological Sciences - May 28, 2013 Category: Neurology Authors: Takao Hoshino, Kentaro Ishizuka, Satoru Shimizu, Shinichiro Uchiyama Tags: Original Articles Source Type: research

Left atrial dilatation is associated with severe ischemic stroke in men with non-valvular atrial fibrillation
and aim Increased left atrial volume is an independent predictive factor of first ischemic stroke and other cardiovascular events in patients with non-valvular atrial fibrillation (NVAF). However, correlations between left atrial dilatation and ischemic stroke severity or ischemic lesion pattern have not been previously reported. The aim of this study was to evaluate whether left atrial enlargement is associated with worse initial stroke severity and lesion patterns.
Source: Journal of the Neurological Sciences - May 13, 2015 Category: Neurology Authors: Tae-Won Kim, Sung-Woo Jung, In-Uk Song, Jaseong Koo, Hyun Seok Choi, Kwang-Soo Lee, Jeong-Wook Park, Hun-Jun Park, Joong-Seok Kim Source Type: research

Duration of paroxysmal atrial fibrillation in cryptogenic stroke is not associated with stroke severity and early outcomes
The current definition of paroxysmal atrial fibrillation (PAF) requires an arbitrary cut-off of>30s, but in clinical practice cryptogenic stroke (CS) patients with PAF duration of ≤30s are not usually excluded from anticoagulation therapy. We sought to evaluate the clinical relevance of short-duration (≤30s) PAF in CS. Consecutive CS patients with no prior AF history and sinus-rhythm on baseline electrocardiography (ECG) were prospectively evaluated over a three-year peri od. Baseline stroke severity was assessed by NIHSS-scores.
Source: Journal of the Neurological Sciences - March 23, 2017 Category: Neurology Authors: Chrissoula Liantinioti, Konstantinos Tympas, Aristeidis H. Katsanos, John Parissis, Maria Chondrogianni, Christina Zompola, Georgios Papadimitropoulos, Michael Ioakeimidis, Sokratis Triantafyllou, Andromaxi Roussopoulou, Konstantinos Voumvourakis, John Le Source Type: research

Ischemic stroke during anticoagulant interruption by healthcare professionals in stroke patients with atrial fibrillation
Anticoagulant therapy often requires temporary interruption. Nevertheless, the frequency and clinical characteristics of stroke patients who develop stroke during anticoagulant interruption are not fully known.
Source: Journal of the Neurological Sciences - March 19, 2019 Category: Neurology Authors: Yuki Sakamoto, Seiji Okubo, Chikako Nito, Yasuhiro Nishiyama, Satoshi Suda, Noriko Matsumoto, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kanako Muraga, Kentaro Suzuki, Masahiro Mishina, Kazumi Kimura Source Type: research

Accurate etiology diagnosis in patients with stroke and atrial fibrillation: A role for brain natriuretic peptide
Atrial fibrillation (AF) is the leading cause of cardioembolic stroke (CES), and patients with stroke and AF are frequently assumed to have CES. However, strokes presumably due to atherosclerotic pathophysiologies in large or small vessels can also occur in patients with AF. The aims of the present study were to clarify the prevalence of and factors related to a non-cardioembolic etiology in acute stroke patients with AF.
Source: Journal of the Neurological Sciences - March 28, 2019 Category: Neurology Authors: Yuki Sakamoto, Chikako Nito, Yasuhiro Nishiyama, Satoshi Suda, Noriko Matsumoto, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kentaro Suzuki, Yuki Go, Masahiro Mishina, Kazumi Kimura Source Type: research

Echocardiographic predictors of cardioembolic stroke due to underlying atrial fibrillation: Reliable left atrial remodeling signs in acute stroke
Atrial remodeling due to high-burden atrial fibrillation (AF) is associated with cardioembolic stroke (CES). As not all CESs is caused by AF, we analyzed the diagnostic values of each echocardiographic parameter to distinguish likely AF-related CES in acute stroke patients while in non-AF rhythm.
Source: Journal of the Neurological Sciences - May 31, 2021 Category: Neurology Authors: Keiko Shimamoto, Hideaki Kanzaki, Tomotaka Tanaka, Atsushi Hirayama, Masatoshi Koga, Kengo F. Kusano, Kazunori Toyoda, Satoshi Yasuda, Masafumi Ihara Source Type: research

Pages: 1  2  3