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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Atrial Fibrillation
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Total 320 results found since Jan 2013.
Dabigatran for Japanese Patients with Atrial Fibrillation and Prior Stroke: A Subgroup Analysis of the J-Dabigatran Surveillance Program
Background: The study objective was to evaluate long-term safety and effectiveness of dabigatran 110 mg and 150 mg twice daily (bid) in patients with nonvalvular atrial fibrillation (NVAF) with a focus on secondary stroke prevention. Methods: In J-Dabigatran Surveillance, 6772 patients newly initiated on dabigatran to prevent ischemic stroke and systemic embolism were enrolled in Japan (1042 sites, December 2011 to November 2013). This subgroup analysis included patients with (1302) and without (5071) previous stroke/transient ischemic attack (TIA).
Source: Journal of Stroke and Cerebrovascular Diseases - February 25, 2020 Category: Neurology Authors: Masahiro Yasaka, Shinichiro Uchiyama, Hirotsugu Atarashi, Ken Okumura, Yukihiro Koretsune, Takeshi Yamashita, Atsushi Taniguchi, Taku Fukaya, Hiroshi Inoue, for the J-Dabigatran Surveillance Investigators Tags: Original article Source Type: research
Factors associated with therapeutic anticoagulation status in patients with ischemic stroke and atrial fibrillation
Understanding factors associated with ischemic stroke despite therapeutic anticoagulation is an important goal to improve stroke prevention strategies in patients with atrial fibrillation (AF). We aim to determine factors associated with therapeutic or supratherapeutic anticoagulation status at the time of ischemic stroke in patients with AF.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2020 Category: Neurology Authors: Shadi Yaghi, Ava L. Liberman, Nils Henninger, Brian Mac Grory, Amre Nouh, Erica Scher, James Giles, Angela Liu, Muhammad Nagy, Ashutosh Kaushal, Idrees Azher, Hiba Fakhri, Kiersten Brown Espaillat, Syed Daniyal Asad, Hemanth Pasupuleti, Heather Martin, Jo Source Type: research
Cholesterol Crystal in Thrombus Removed by Mechanical Thrombectomy Should be a Strong Marker for Aortogenic Embolic Stroke
Aortogenic embolic stroke (AES) is an important stroke mechanism. However, as many stroke patients have aortic atheromatous lesions, it is unclear whether these lesions are the cause of these strokes. Cholesterol crystals are the solid, crystalline form of cholesterol that is found in atherosclerosis, but not in cardiac diseases such as atrial fibrillation, valvular diseases, and cardiomyopathy. Therefore, if a cholesterol crystal is found in a thrombus removed by mechanical thrombectomy (MT), this makes it possible to diagnose a patient as having an atheromatous lesion.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Noriko Matsumoto, Mizuho Takahashi, Takehiro Katano, Akihito Kutsuna, Takuya Kanamaru, Yuki Sakamoto, Kentaro Suzuki, Junya Aoki, Yasuhiro Nishiyama, Shinobu Kunugi, Akira Shimizu, Kazumi Kimura Tags: Case Report Source Type: research
Anticoagulation Choice and Timing in Stroke Due to Atrial Fibrillation: A Survey of US Stroke Specialists (ACT-SAFe)
Risk of early recurrent ischemic stroke in patients with atrial fibrillation may be high. ASA/AHA guidelines provide imprecise recommendations on the timing and anticoagulant choice for this indication. We assessed current opinions of stroke neurologists.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Igor Rybinnik, Stephen Wong, Deviyani Mehta, Ronen R. Leker, Michael T. Mullen, Steven R. Mess é, Scott E. Kasner, Brett Cucchiara Source Type: research
Stroke-Related Visual Impairment; is There an Association with Atrial Fibrillation?
This study explores whether presence of visual impairment following stroke is associated with presence of atrial fibrillation (AF).
Source: Journal of Stroke and Cerebrovascular Diseases - August 23, 2020 Category: Neurology Authors: Fiona J Rowe, Lauren R Hepworth, Claire Howard, Claire Cullen, Benjamin Sturgess, Natalie Griffiths, Gregory Y H Lip Source Type: research
Insights Into Direct Oral Anticoagulant Therapy Implementation of Stroke Survivors with Atrial Fibrillation in an Ambulatory Setting
Atrial fibrillation (AF) is the most common cardiac arrhythmia and increases the risk of ischemic stroke by about five times.1 Oral anticoagulation (OAC) with direct oral anticoagulants (DOAC) or vitamin K antagonists (VKA) reduces ischemic stroke risk in AF patients. Currently, DOAC (apixaban, dabigatran, edoxaban and rivaroxaban) are recommended as first-line treatment for stroke prevention in AF patients.2 Despite several advantages compared to VKA, DOAC have a short half-life of about 12 h. Missing more than 5% of intakes is associated with a higher occurrence of thromboembolic events in OAC-treated AF patients.
Source: Journal of Stroke and Cerebrovascular Diseases - December 14, 2020 Category: Neurology Authors: Valerie Albert, Alexandros A. Polymeris, Fine Dietrich, Stefan T. Engelter, Kurt E. Hersberger, Sabine Schaedelin, Philippe A. Lyrer, Isabelle Arnet Source Type: research
Anticoagulation Protocol for Secondary Prevention of Acute Ischemic Stroke Associated with Nonvalvular Atrial Fibrillation
Atrial fibrillation (AF) is a major risk factor for ischemic stroke and despite evidence for the efficacy of anticoagulation for secondary prevention of recurrent stroke in patients with AF,1 to date there is no established evidence regarding the timing for initiation of oral anticoagulants (OACs), including direct oral anticoagulants (DOACs), for secondary prevention of acute ischemic stroke associated with AF. Of concern in early initiation of OACs is the risk of recurrence balanced with the risk of hemorrhagic transformation (HT) after vascular reperfusion with reports of 3.6% symptomatic cerebral bleeding for acute use of OACs.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2021 Category: Neurology Authors: Teruo Kimura, Adam Tucker, Atsushi Nakagaki, Toshihide Sugimura, Shin Fukuda, Makoto Katsuno, Tsutomu Fujita, Naoto Izumi, Nozomi Suzuki, Kazuhiro Sako Source Type: research
Effects of Sodium/Glucose Cotransporter Inhibitors on Atrial Fibrillation and Stroke: A Meta-Analysis
Globally, the number of people estimated to have diabetes mellitus (DM) in 2019 was 463 million, and the estimated number is expected to rise to 578 million people by 2030.1 DM is also associated with an increased risk of atrial fibrillation (AF), 2 and has shown to be an independent risk factor for stroke in patients with AF.3 A meta-analysis of 102 studies further showed that patients with diabetes have a higher risk of all subtypes of stroke (ischemic, hemorrhagic and unclassified stroke).4 This has generated great interest in anti-hyperglycemic agents and their ability to reduce the cardiovascular complications of diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 22, 2021 Category: Neurology Authors: How Ting Ong, Yao Hao Teo, Yao Neng Teo, Nicholas LX Syn, Caitlin Fern Wee, Shariel Leong, Alicia Swee Yan Yip, Ray Meng See, Adriel Zhi Hen Ting, Alys ZQ Chia, Alex Jia Yang Cheong, Benjamin Yong-Qiang Tan, Jamie Sin-Ying Ho, Leonard Leong-Litt Yeo, Aloy Source Type: research
Impact of Arrhythmia in Hospital Mortality in Acute Ischemic Stroke Patients: A Retrospective Cohort Study in Northern Mexico
Stroke remains one of the leading causes of death globally. 1 In Mexico, it represents the 6th cause of death2 and contributes with 688.19 DALYs per 100,000 people,3 constituting a major cause of burden of disease in the country. Heart rhythm dysfunctions following acute ischemic strokes (AIS) have been previously reported,4 –9 and it is expected that 25-30% of patients will be diagnosed with any type of arrhythmia after stroke.6,9 Kallmünze et al. reported the incidence of several post-stroke arrhythmias, such as atrial fibrillation (AF), focal atrial tachycardia, undetermined supraventricular tachycardia, ventricu la...
Source: Journal of Stroke and Cerebrovascular Diseases - December 16, 2021 Category: Neurology Authors: J. De la Fuente-Mart ínez, A. Infante-Valenzuela, D. Martínez-Roque, M. Cruz-Moreno, F. Góngora-Rivera Source Type: research
Assessment of Serum IgG Titers to Various Periodontal Pathogens Associated with Atrial Fibrillation in Acute Stroke Patients
There is accumulating evidence that periodontal disease is associated with atrial fibrillation (AF) or stroke, but it is unclear which causative species of periodontal disease are present in stroke patients with AF. We aimed to investigate the associations between AF and specific periodontal pathogens using serum titers of IgG antibodies of bacteria in acute stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2022 Category: Neurology Authors: Tomohisa Nezu, Naohisa Hosomi, Shiro Aoki, Hiromi Nishi, Masahiro Nakamori, Yuji Shiga, Eiji Imamura, Tomoaki Shintani, Hiroyuki Kawaguchi, Hirofumi Maruyama Tags: Short Communication Source Type: research
Holter ECG monitoring for the evaluation of stroke in the internal medicine department
Holter ECG is an external device for cardiac monitoring, connected by electrodes to the patient. The Holter performs a continuous recording of the cardiac electrical activity, which is used to reveal an underling arrhythmia.1 Diagnosing an arrythmia among stroke patients, especially atrial fibrillation/flutter (AF), is of significant influence, indicating a hypothetic cardio-embolic source with increased risk of recurrent stroke.2 –4 Once AF is found, anticoagulant therapy, rather than antiplatelet therapy, is recommended for secondary stroke prevention.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2022 Category: Neurology Authors: Inbar Caspi, Ophir Freund, Roni Biran, Gil Bornstein Tags: Short Communication Source Type: research
Enlarged left atrium may be associated with laterality of anterior circulation cardioembolic stroke
In this study, we compared the hemispheric differences among patients with AF-stroke and identified factors associated with lesion laterality.
Source: Journal of Stroke and Cerebrovascular Diseases - January 21, 2023 Category: Neurology Authors: Sang Hee Ha, So Young Yang, Soo Jeong, Jae Young Park, Jun Young Chang, Dong-Wha Kang, Sun U. Kwon, Jong-Sung Kim, Bum Joon Kim Tags: Short Communication Source Type: research
Pulmonary hypertension: An unexplored risk factor for stroke in patients with atrial fibrillation
Atrial fibrillation (Afib) is one of the most common and significant risk factors for stroke, with the CHADsVAsc score used as the tool for stroke risk assessment. Pulmonary hypertension (PH) has not been studied as an independent risk factor for stroke in individuals with Afib.
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2023 Category: Neurology Authors: Georges Khattar, Ahmad Mustafa, Fasih Sami Siddiqui, Khalil El Gharib, Wei Chapman, Saif Abu Baker, Saud Bin Abdul Sattar, Dany Elsayegh, Halim El-Hage, Suzanne El Sayegh, Michel Chalhoub Source Type: research
Higher Frequency of Atrial Fibrillation Linked to Colder Seasons and Air Temperature on the Day of Ischemic Stroke Onset
We read with great interest the article published by Fustinoni et al entitled “Higher frequency of atrial fibrillation linked to colder seasons and air temperature on the day of ischemic stroke onset” in the Journal of Stroke and Cardiovascular Diseases. We have recently analyzed Nationwide Inpatient Sample, a nationally representative survey of hospitalizations in the United States and found that there is a substantial increase in atrial fibrillation (AF)–related hospitalization in colder months and decreased hospitalization in warmer months. Such findings have been replicated from other nations as well. Environme...
Source: Journal of Stroke and Cerebrovascular Diseases - July 19, 2013 Category: Neurology Authors: Sadip Pant, Apurva O. Badheka, Abhishek Deshmukh Tags: Letters to the Editor Source Type: research
Rivaroxaban versus Warfarin in Japanese Patients with Nonvalvular Atrial Fibrillation for the Secondary Prevention of Stroke: A Subgroup Analysis of J-ROCKET AF
Conclusions: The safety and efficacy profile of rivaroxaban compared with warfarin was consistent among patients in the primary prevention group and those in the secondary prevention group.
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2013 Category: Neurology Authors: Norio Tanahashi, Masatsugu Hori, Masayasu Matsumoto, Shin-ichi Momomura, Shinichiro Uchiyama, Shinya Goto, Tohru Izumi, Yukihiro Koretsune, Mariko Kajikawa, Masaharu Kato, Hitoshi Ueda, Kazuya Iwamoto, Masahiro Tajiri, J-ROCKET AF Study Investigators Tags: Original Articles Source Type: research
