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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Atrial Fibrillation
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Total 320 results found since Jan 2013.
Anticoagulation under-utilization in atrial fibrillation patients is responsible for a large proportion of strokes requiring endovascular therapy
Atrial fibrillation (AF) is responsible for 30-50% of large strokes requiring endovascular thrombectomy (EVT). Anticoagulation (AC) underutilization is a common source of AF-related stroke. We compared antithrombotic medications among stroke patients with AF that did or did not undergo EVT to determine if AC underutilization disproportionately results in strokes requiring EVT, while quantifying the proportion of likely preventable thrombectomies.
Source: Journal of Stroke and Cerebrovascular Diseases - January 10, 2023 Category: Neurology Authors: Banafsheh Shakibajahromi, Scott E. Kasner, Catherine Schmitt, Christopher G. Favilla Source Type: research
Aspirin Therapy and Risk of Subdural Hematoma: Meta-analysis of Randomized Clinical Trials
Conclusions: Based on the limited available data, it is uncertain whether aspirin therapy increases the risk of subdural hematoma: the observed 1.6-fold increased risk was not statistically significant. The incidence of subdural hematoma during aspirin therapy is low but varies widely depending upon the age of the patient population.
Source: Journal of Stroke and Cerebrovascular Diseases - February 18, 2013 Category: Neurology Authors: Ben J. Connolly, Lesly A. Pearce, Tobias Kurth, Carlos S. Kase, Robert G. Hart Tags: Original Articles Source Type: research
Examination Timing and Lesion Patterns in Diffusion-weighted Magnetic Resonance Imaging of Patients with Classically Defined Transient Ischemic Attack
Conclusions: Acute ischemic lesions on DWI were associated with time-to-DWI and LAA in patients with classically defined TIA. Additionally, we identified some differences in relating factors between patients with single and multiple DWI lesions. These results indicate that time-to-DWI and DWI lesion pattern may be important for the diagnosis and management of TIA.
Source: Journal of Stroke and Cerebrovascular Diseases - January 24, 2013 Category: Neurology Authors: Tetsuya Miyagi, Toshiyuki Uehara, Kazumi Kimura, Yasushi Okada, Yasuhiro Hasegawa, Norio Tanahashi, Akifumi Suzuki, Shigeharu Takagi, Jyoji Nakagawara, Kazumasa Arii, Shinji Nagahiro, Kuniaki Ogasawara, Takehiko Nagao, Shinichiro Uchiyama, Masayasu Matsum Tags: Original Articles Source Type: research
Net Clinical Benefit of Rivaroxaban versus Warfarin in Japanese Patients with Nonvalvular Atrial Fibrillation: A Subgroup Analysis of J-ROCKET AF
Conclusion: Analysis of the NCB supports that rivaroxaban therapy provides clinical benefit for Japanese patients with AF.
Source: Journal of Stroke and Cerebrovascular Diseases - November 4, 2013 Category: Neurology Authors: Shinichiro Uchiyama, Masatsugu Hori, Masayasu Matsumoto, Norio Tanahashi, Shin-ichi Momomura, Shinya Goto, Tohru Izumi, Yukihiro Koretsune, Mariko Kajikawa, Masaharu Kato, Hitoshi Ueda, Kazuma Iekushi, Satoshi Yamanaka, Masahiro Tajiri, J-ROCKET AF Study Tags: Original Articles Source Type: research
Diagnostic Accuracy and Risk Factors of the Different Lacunar Syndromes
Conclusions: The clinical diagnosis of patients with lacunar syndromes is inaccurate, especially among patients with sensorimotor syndrome. DWI is mandatory for obtaining an accurate diagnosis of the infarct.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2014 Category: Neurology Authors: Marianne Altmann, Bente Thommessen, Ole Morten Rønning, Antje S. Reichenbach, Brynjar Fure Tags: Original Articles Source Type: research
Incidence, Mortality, and Risk Factors for Oral Anticoagulant–associated Intracranial Hemorrhage in Patients with Atrial Fibrillation
Warfarin, a vitamin K epoxide reductase inhibitor, is the oral anticoagulant most commonly used to reduce the risk of stroke in patients with atrial fibrillation (AF). Warfarin has proved to be efficacious for this purpose in multiple clinical trials. However, warfarin use is laborious and associated with an increased risk of intracranial hemorrhage (ICH). Various factors increase the risk of warfarin-related ICH, including older age, intensity of anticoagulation, hypertension, and history of cerebrovascular disease.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2014 Category: Neurology Authors: Rebbeca Grysiewicz, Philip B. Gorelick Tags: Review Article Source Type: research
Embolic Stroke during Apixaban Therapy for Left Atrial Appendage Thrombus
Left atrial appendage (LAA) thrombus is associated with atrial fibrillation (AF) and is a powerful predictor of cardiogenic thromboembolism. Warfarin is an established anticoagulant therapy for patients with LAA thrombus to prevent thromboembolic complications. Apixaban is superior to warfarin in the prevention of thromboembolic complications in patients with AF, and there are case reports showing apixaban-associated resolution of LAA thrombus; however, the efficacy and safety of apixaban for the treatment of LAA thrombus remains unproven.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2015 Category: Neurology Authors: Masaki Ohyagi, Kazuha Nakamura, Mutsufusa Watanabe, Hiroto Fujigasaki Tags: Case Report Source Type: research
Intratumoral Hemorrhage in a Patient with Malignant Meningioma under Anticoagulant Therapy
We report the case of an elderly woman with malignant meningioma and atrial fibrillation who started taking anticoagulants after an ischemic stroke and subsequently developed intratumoral hemorrhage. Further studies are required to confirm whether a particular anticoagulant agent is suitable for patients with brain tumor and atrial fibrillation.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2015 Category: Neurology Authors: Yasuyuki Ito, Makoto Nakajima, Mari Watari, Tetsuro Sakamoto, Yoichiro Hashimoto, Seiji Tajiri, Akira Takada, Yukio Ando Tags: Case Report Source Type: research
Left Atrial Volume Index Predicts Recurrence of Stroke in Patients with Nonsustained Atrial Tachycardia
Nonsustained atrial tachycardia (NSAT) is known to appear more frequently in patients with paroxysmal atrial fibrillation (AF). Enlarged left atrium (LA) is considered to be an independent risk factor for newly diagnosed AF.
Source: Journal of Stroke and Cerebrovascular Diseases - August 10, 2015 Category: Neurology Authors: Hyemoon Chung, Boyoung Joung, Kyung-Yul Lee, Jae-Sun Uhm, Hui-Nam Pak, Moon-Hyoung Lee, Jong-Youn Kim Source Type: research
Effects of Pretreatment with Warfarin or Rivaroxaban on Neurovascular Unit Dissociation after Tissue Plasminogen Activator Thrombolysis in Ischemic Rat Brain
In this study, we assessed the risks and benefits of pre-treatment with warfarin or rivaroxaban after tissue-type plasminogen activator (tPA) thrombolysis in ischemic rat brain.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2016 Category: Neurology Authors: Jingwei Shang, Toru Yamashita, Syoichiro Kono, Ryuta Morihara, Yumiko Nakano, Yusuke Fukui, Xianghong Li, Nozomi Hishikawa, Yasuyuki Ohta, Koji Abe Source Type: research
The Sex, Age, Medical History, Treatment, Tobacco Use, Race Risk (SAMe TT2R2) Score Predicts Warfarin Control in a Singaporean Population
Warfarin reduces stroke risk in atrial fibrillation (AF) patients but requires ongoing monitoring. Time in therapeutic range (TTR) is used as a measure of warfarin control, with a TTR less than 60% associated with adverse patient outcomes. The Sex, Age, Medical history, Treatment, Tobacco use, Race (SAMe-TT2R2) score has been identified as a model able to predict warfarin control, but this has been tested in mainly Caucasian populations. Therefore, the aim of this study was to determine the ability of the SAMe-TT2R2 score to predict warfarin control in a Singaporean population consisting of Chinese, Malay, and Indian race.
Source: Journal of Stroke and Cerebrovascular Diseases - September 22, 2016 Category: Neurology Authors: Nijole Bernaitis, Chi Keong Ching, Liping Chen, Jin Shing Hon, Siew Chong Teo, Andrew K. Davey, Shailendra Anoopkumar-Dukie Source Type: research
Suboptimal Anticoagulant Management in Japanese Patients with Nonvalvular Atrial Fibrillation Receiving Warfarin for Stroke Prevention
Atrial fibrillation (AF) is the most common cardiac arrhythmia, with increasing prevalence in Japan. Although prothrombin time –international normalized ratio (PT-INR) targets for monitoring warfarin therapy in patients with nonvalvular AF (NVAF) are well defined, real-world patient characteristics and PT-INR levels remain unknown among Japanese patients with NVAF who initiate and continue warfarin (warfarin maintainers) versus those who switch from warfarin to direct oral anticoagulants (DOACs; warfarin switchers).
Source: Journal of Stroke and Cerebrovascular Diseases - May 19, 2017 Category: Neurology Authors: Teruyuki Hirano, Hirokazu Kaneko, Sari Mishina, Feng Wang, Satoshi Morita Source Type: research
Anticoagulant-Free but Dangerous: Perisurgical Consideration
It is recognized that anticoagulants should be withdrawn before surgery or invasive tests for the recommended period. However, it is not well known when anticoagulants should restart. For the past 12 months, we had 5 patients who suddenly developed ischemic stroke after a prolonged withdrawal of anticoagulants for atrial fibrillation.
Source: Journal of Stroke and Cerebrovascular Diseases - July 12, 2017 Category: Neurology Authors: Yosuke Aiba, Ryuji Sakakibara, Yohei Tsuyusaki, Masahiko Kishi, Fuyuki Tateno, Tsuyoshi Ogata, Takeki Nagao, Hitoshi Terada, Tsutomu Inaoka Tags: Letter to the Editor Source Type: research
Therapeutic Decisions in Atrial Fibrillation for Stroke Prevention: The Role of Aversion to Ambiguity and Physicians' Risk Preferences
Knowledge-to-action gaps influence therapeutic decisions in atrial fibrillation (AF). Physician-related factors are common, but the least studied. We evaluated the prevalence and determinants of physician-related factors and knowledge-to-action gaps among physicians involved in the management of AF patients.
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2018 Category: Neurology Authors: Luciano A. Sposato, Devin Stirling, Gustavo Saposnik Source Type: research
