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Source: International Journal of Cardiology
Condition: Atrial Fibrillation

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Total 388 results found since Jan 2013.

Current clinical practice of transesophageal echocardiography and cardiac computed tomography prior to atrial fibrillation ablation in Canada
Pulmonary vein isolation (PVI) is the procedure of choice in patients with symptomatic atrial fibrillation (AF) who failed antiarrhythmic drugs [1]. Preprocedurally, cardiac computed tomography (CCT) is required to define the left atrium (LA) and the pulmonary veins (PV) on which to superimpose an electrical map [1]. Patients also routinely undergo transesophageal echocardiography (TEE) to rule out the presence of LA/left atrial appendage (LAA) thrombus, which is an absolute contraindication to the procedure due to the increased risk of stroke [1].
Source: International Journal of Cardiology - March 25, 2015 Category: Cardiology Authors: Sara Awad, Kiarash Mohajer, Adrian Baranchuk, Raveen S. Pal Tags: Letter to the Editor Source Type: research

The effects of angiotensin receptor blockers on outcomes of Chinese patients with atrial fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia, current estimated global prevalence of AF is 1-2% among the general population [1], and it is associated with a 5-fold risk of stroke and 3-fold incidence of congestive heart failure, and higher mortality and morbidity [1].The pathogenesis of AF is multifactorial, both the electrical remodeling and structural remodeling are involving in the initial and maintenance of this arrhythmia [2]. Recently, evidence shows that the renin-angiotensin-aldosterone system (RAAS) has been involved in both atrial structural remodeling and electrical remodeling [2].
Source: International Journal of Cardiology - March 25, 2015 Category: Cardiology Authors: Juan Wang, Yan-min Yang, Jun Zhu, Xing-hui Shao, Han Zhang, Bi Huang, Huai-bin Wan Tags: Letter to the editor Source Type: research

Meta-analysis of Major bleeding with uninterrupted warfarin compared to interrupted warfarin and heparin bridging in ablation of atrial fibrillation
The role of catheter ablation procedures of Atrial fibrillation are increasing in importance and recent AHA/ACC guidelines give a class I recommendation for ablation in symptomatic paroxysmal atrial fibrillation who are intolerant or refractory to at least one antiarrhythmic medication [1]. Anticoagulation strategies peri-ablation are of extreme importance as it relates to both thrombo-embolic and bleeding complications. A strategy of stopping warfarin and bridging with heparin was widely adopted however a strategy of performing ablation on continued therapeutic warfarin is gaining traction as it was shown in a recent meta...
Source: International Journal of Cardiology - March 27, 2015 Category: Cardiology Authors: Ramez Nairooz, Partha Sardar, Jason Payne, Wilbert S. Aronow, Hakan Paydak Tags: Letter to the Editor Source Type: research

Relationship between left atrial appendage morphology and thrombus formation in patients with atrial fibrillation
Atrial fibrillation (AF) is the most common chronic arrhythmia seen in clinical practice and is associated with increased risk of systemic thromboembolism. However, scoring systems such as CHADS2 score and CHA2DS2VASc score for assessing stroke risk were still plagued with limitations [1,2]. About 90% of the thrombus was detected in left atrial appendage (LAA) [3], which can be identified by transoesophageal echocardiography (TEE), an invasive test with some risk of complications [4]. Computed tomography (CT), on the other hand, is non-invasive and may provide more details about the morphology of the LAA [5].
Source: International Journal of Cardiology - April 6, 2015 Category: Cardiology Authors: Yan Zhao, Peng-Pai Zhang, Quan-Fu Xu, Ling-Wei Yu, Yi Yu, Yi-Gang Li Tags: Letter to the Editor Source Type: research

Uninterrupted Dabigatran versus Warfarin in the Treatment of Intracardiac Thrombus in Patients with non-Valvular Atrial Fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical practice and increases the risk of thrombus in the left atrial appendage (LAA) which is strongly associated with an increased risk of ischemic stroke [1, 2]. Embolic strokes caused by AF are typically severe, more commonly disabling and fatal compared with strokes not associated with AF [1, 3]. Transesophageal echocardiography (TEE) is a sensitive method for intracardiac thrombus identification. When AF lasts for 2 days, atrial thrombi may take place in up to 14% patients on TEE examination; the prevalence of thrombus in AF patients varies from 10% ...
Source: International Journal of Cardiology - April 15, 2015 Category: Cardiology Authors: Li Hao, Jing-quan Zhong, Wei Zhang, Bing Rong, Fei Xie, Jun-tao Wang, Xin Yue, Zhao-tong Zheng, Qing Zhu, Yun Zhang Tags: Letter to the Editor Source Type: research

Massive Left Ventricular Calcification
94-year-old male presented for follow-up for shortness of breath. He has a history of two episodes of anterior and inferior myocardial infarction (MI) (eight and thirteen years ago) with stent revascularization, ischemic cardiomyopathy, implantable cardioverter defibrillator, paroxysmal atrial fibrillation, hypertension, hyperlipidemia, diabetes, and stroke. Lab investigation showed normal kidney function and calcium level. Echocardiography showed a reduced left ventricular (LV) ejection fraction of 25%, diastolic dysfunction, severe anteroseptal hypokinesis, otherwise normal LV.
Source: International Journal of Cardiology - April 28, 2015 Category: Cardiology Authors: Anas Alani Tags: Letter to the Editor Source Type: research

Asymptomatic Versus Symptomatic Atrial Fibrillation: A Systematic Review of Age/Gender Differences and Cardiovascular Outcomes
Up to 40% of atrial fibrillation (AF) patients are asymptomatic. Despite this, scarce data are available about asymptomatic AF, with regard to its clinical profile and relationship to cerebrovascular and cardiovascular risk. Our objective was to conduct a systematic review and meta-analysis was to study the relationship between age and gender with asymptomatic AF and to establish whether patients with asymptomatic AF have a higher risk of death (all cause and cardiovascular) and stroke/systemic thromboembolism, when compared to symptomatic AF patients.
Source: International Journal of Cardiology - May 7, 2015 Category: Cardiology Authors: Qinmei Xiong, Marco Proietti, Keitaro Senoo, Gregory Y.H. Lip Tags: Review Source Type: research

Anti-platelet or Anti-coagulant Agent for Prevention of Ischemic Stroke in Patients with End-Stage Renal Disease and Atrial Fibrillation, is it necessary?
We just received comments by Chen et al on our recent article about whether anti-platelet or anticoagulant agent should be used in patients with end-stage renal disease and atrial fibrillation [1]. There are some points that need to be clarified.
Source: International Journal of Cardiology - May 30, 2015 Category: Cardiology Authors: Jien-Jiun Chen, Lian-Yu Lin, Yao-Hsu Yang, Juey-Jen Hwang, Pau-Chung Chen, Jiunn-Lee Lin Tags: Letter to the Editor Source Type: research

Myasthenia gravis. A potential cause of false positively elevated troponin T? Case report and brief review
Both cardiac troponin T (cTnT) and I (cTnI) are the biomarkers of choice for the evaluation of patients with possible cardiac injury [1]. Myocardial ischemia remains the most frequent primary cardiac cause of troponin-T positivity (59%). Atrial fibrillation, heart failure, renal insufficiency, chronic obstructive lung disease, acute stroke and infections may also produce troponin elevation, a potential [2]. Several neuromuscular diseases have been associated with troponin-T positivity [3]. These patients may show increases in cTnT and CK-MB concomitantly, but not in cTnI which is related to the underlying skeletal muscle d...
Source: International Journal of Cardiology - July 4, 2015 Category: Cardiology Authors: G. Stavroulakis, M. Papadopoulou, G. Koutroulis, V. Zouvelou, J. Katsavochristos, E. Georgiadis, C. Baltogiannis, G. Avrampos Source Type: research

Predictive Accuracy Of CHADS-VASc and HAS-BLED Scores In Patients Without Atrial Fibrillation Undergoing Percutaneous Coronary Intervention And Discharged On Dual Antiplatelet Therapy
The CHA2DS2-VASc and HAS-BLED are well-validated stroke risk prediction scores for atrial fibrillation (AF), but their role in risk stratification of major adverse cardiac events (MACE) and major bleeding for non-AF patients undergoing percutaneous coronary intervention (PCI) is unknown.
Source: International Journal of Cardiology - July 25, 2015 Category: Cardiology Authors: Davide Capodanno, Roberta Rossini, Giuseppe Musumeci, Corrado Lettieri, Michele Senni, Orazio Valsecchi, Dominick J. Angiolillo, Gregory Y.H. Lip Source Type: research

Inadequate anticoagulation by warfarin is associated with major adverse cardiovascular events in patients with atrial fibrillation
Time in therapeutic range (TTR) reflects the quality of anticoagulation and is inversely correlated with ischemic stroke in atrial fibrillation (AF) patients. Few data on the relationship between TTR and myocardial infarction (MI) are available. We investigated the association between TTR and Major Adverse Cardiovascular Events (MACE) in a cohort of anticoagulated AF patients.
Source: International Journal of Cardiology - August 4, 2015 Category: Cardiology Authors: Daniele Pastori, Pasquale Pignatelli, Mirella Saliola, Roberto Carnevale, Tommasa Vicario, Maria Del Ben, Roberto Cangemi, Francesco Barillà, Gregory Y.H. Lip, Francesco Violi Source Type: research

Vagal atrial fibrillation: what is it and should we treat it?
Vagal atrial fibrillation (AF) remains an under-recognised entity, affecting younger patients often with structurally normal hearts. Although there remains no universal definition or diagnostic criteria, in this review we describe recognised triggers and associated features, including a well-established association with athletic training. We explore potential mechanisms, including the role of the autonomic nervous system and ganglionated plexi in initiating and maintaining the arrhythmia. We discuss the limited evidence base addressing the question of progression to persistent AF, and debate the merits of anti-arrhythmic t...
Source: International Journal of Cardiology - August 10, 2015 Category: Cardiology Authors: Alexander Carpenter, Antonio Frontera, Richard Bond, Edward Duncan, Glyn Thomas Source Type: research

Chronic Obstructive Pulmonary Disease in Patients with Atrial Fibrillation: Insights from the ARISTOTLE Trial
Comorbid chronic obstructive pulmonary disease (COPD) is associated with poor outcomes among patients with cardiovascular disease. The risks of stroke and mortality associated with COPD among patients with atrial fibrillation are not well understood.
Source: International Journal of Cardiology - September 22, 2015 Category: Cardiology Authors: Michael T. Durheim, Derek D. Cyr, Renato D. Lopes, Laine E. Thomas, Wayne M. Tsuang, Bernard J. Gersh, Claes Held, Lars Wallentin, Christopher B. Granger, Scott M. Palmer, Sana M. Al-Khatib Source Type: research

Atrial Myxomas and different clinical presentations
Primary cardiac tumors are rare diseases and Myxomas are the most common among them. Interesting is their heterogeneity in clinical presentation. These differences include silent forms with benign clinical course, cardioembolic stroke, angina pectoris, atrial fibrillation, myocardial infarction, paraneoplastic syndromes, syncope. [1–16]
Source: International Journal of Cardiology - September 22, 2015 Category: Cardiology Authors: F. Messina, P. Romano, S. Crosca Source Type: research

TEMPORARY REMOVAL: REal-LIfe Evidence of stroke prevention in patients with atrial Fibrillation – the RELIEF study
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
Source: International Journal of Cardiology - September 21, 2015 Category: Cardiology Authors: Craig I. Coleman, Matthias Antz, Birgit Ehlken, Thomas Evers Source Type: research