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Source: International Journal of Cardiology
Condition: Atrial Fibrillation
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Total 388 results found since Jan 2013.
One for all and all for one? The dilemma of optimal management of atrial fibrillation with cardiac co-morbidities
Patients with non-valvular atrial fibrillation (AF) and concomitant heart failure or coronary artery disease (CAD) are at particularly high risk of thromboembolic complications, requiring careful stroke prevention management. The development of the direct oral anticoagulants has undoubtedly improved secondary prevention of stroke arising from venous sources, while antiplatelet therapy is an essential mainstay of secondary prevention in patients with CAD. The combination, however, is associated with an increased risk of major bleeds, so the decision whether to continue with antiplatelet treatment on top of life-long anticoa...
Source: International Journal of Cardiology - October 6, 2019 Category: Cardiology Authors: Anke C. Fender, Dobromir Dobrev Source Type: research
Oral anticoagulation and cardiovascular outcomes in patients with atrial fibrillation and chronic kidney disease in Asian Population,Data from the COOL-AF Thailand registry
Patients with AF and chronic kidney disease(CKD) encountered increased risks of stroke, bleeding, morbidity, and overall mortality. Oral anticoagulation in these populations definitely enhances major bleeding but the benefit of stroke reduction remained inconclusive.The aim of this study is to evaluate the effect of oral anticoagulation (OAC) on the 2-year cardiovascular outcomes in patients with AF and CKD .
Source: International Journal of Cardiology - August 19, 2020 Category: Cardiology Authors: Thoranis Chantrarat, Rungroj Krittayaphong Source Type: research
The anticoagulation dilemma and future treatment avenues in patients with breast cancer and atrial fibrillation
Atrial fibrillation (AF) is the most common arrhythmia, with a substantial rise in global incidence and prevalence. Ischemic stroke is a frequent complication of AF, since AF perfectly fulfills Virchow's triad of blood stasis, vascular damage and hypercoagulation, making oral anticoagulation (OAC) obligatory for stroke prevention. Direct oral anticoagulants (DOAC), such as dabigatran, which inhibits thrombin, and apixaban, edoxaban and rivaroxaban, which block the activated coagulation factor X (FXa), have some advantages and are largely replacing coumarin-based OAC.
Source: International Journal of Cardiology - September 30, 2020 Category: Cardiology Authors: Anke C. Fender, Dobromir Dobrev Tags: Editorial Source Type: research
No antiarrhythmic effect of direct oral anticoagulants versus vitamin K antagonists in paroxysmal atrial fibrillation patients undergoing catheter ablation
Direct oral anticoagulants (DOACs) are superior to vitamin K antagonists (VKAs) for the prevention of stroke in atrial fibrillation (AF) patients with elevated stroke risk. Possible antiarrhythmic effects of DOACs have been discussed. We analyzed impact of DOAC treatment on recurrence-free survival after AF catheter ablation.
Source: International Journal of Cardiology - January 25, 2021 Category: Cardiology Authors: David Zweiker, Martin Manninger, Raphael Sieghartsleitner, Jakob Ebner, Bernadette Pratl, Egbert Bisping, Peter Lercher, Dirk von Lewinski, Rita Riedlbauer, Ursula Rohrer, Henri M.H. Spronk, Andreas Zirlik, Ulrich Schotten, Daniel Scherr Tags: Short communication Source Type: research
Percutaneous left atrial appendage closure vs oral anticoagulation: The scariest might be the cheepest
Left Atrial Appendage Closure (LAAC) in patients with atrial fibrillation (AF) and consequent elevated risk of thromboembolic events has an excellent safety profile, with an equal efficacy in preventing stroke, compared with vitamin K antagonists in patients without contraindications to oral anticoagulants [1]. It is also noninferior to direct oral anticoagulants (DOACs) in preventing major AF-related ischemic and haemorrhagic events [2]. Nevertheless, according to the current practice guidelines, percutaneous LAAC is still recommended only in patients with AF at increased risk of stroke and with contraindications to long-term OAC [3,4].
Source: International Journal of Cardiology - January 29, 2022 Category: Cardiology Authors: Patrizio Mazzone, Paolo Della Bella, Francesca Baratto Tags: Editorial Source Type: research
Assessment of atrial function by echocardiography: Can this be used to assess the arrhythmogenic atrial substrate?
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia. It is associated with a high risk for thromboembolic stroke, heart failure, decreased quality of life and cognitive impairment, all increasing mortality. After confirmation of AF, comprehensive assessment of i) stroke risk, ii) symptom severity, iii) severity of AF-burden and iv) atrial substrate severity is recommended in accordance with the 4S-AF scheme proposed by the current European AF-guidelines to provide optimal treatment for the individual patient [1].
Source: International Journal of Cardiology - June 1, 2022 Category: Cardiology Authors: Florian Bruns, Dobromir Dobrev Tags: Editorial Source Type: research
iPhone ECG application for community screening to detect silent atrial fibrillation: A novel technology to prevent stroke
Atrial fibrillation (AF) is the most common sustained arrhythmia, and its prevalence increases with age. In those aged 65 or older, screening studies reveal the prevalence (in AF at time of screening) to be 4.4%, with 1.4% of those having previously undiagnosed AF . In our own study of ambulant patients, 6.7% of those ≥65years were in AF and in 10% of these, AF was incidentally detected, most without symptoms of palpitations or the elevation of resting heart rate .
Source: International Journal of Cardiology - February 27, 2013 Category: Cardiology Authors: Jerrett K. Lau, Nicole Lowres, Lis Neubeck, David B. Brieger, Raymond W. Sy, Connor D. Galloway, David E. Albert, Saul B. Freedman Tags: Letters to the Editor Source Type: research
Eligibility of patients with atrial fibrillation for new oral anticoagulants
Vitamin K antagonists (VKA) have been the mainstay of antithrombotic therapy in atrial fibrillation (AF) for decades but have major limitations such as multiple food and drug interactions, a metabolism affected by genetic polymorphisms, a narrow therapeutic window, and a need for regular monitoring of the international normalized ratio. Many patients with AF at moderate or high risk of stroke are not prescribed VKAs . Novel oral anticoagulants (OACs), thrombin inhibitors (dabigatran) or factor Xa inhibitors (rivaroxaban and apixaban), have proven their efficacy in the prevention of strokes and systemic embolism in large ra...
Source: International Journal of Cardiology - October 2, 2012 Category: Cardiology Authors: Ghassan Moubarak, Nicolas Badenco, Julien Dreyfus, Constantin Simion, Aurélie Delos Paquet, Serge Cazeau, Romain Cador Tags: Letters to the Editor Source Type: research
Comparison of the reliability and validity of four contemporary risk stratification schemes to predict thromboembolism in non-anticoagulated patients with atrial fibrillation
Conclusions: Compared to ACC/AHA/ESC, 8th ACCP, and Framingham, CHA2DS2-VASc risk stratification schema may be better in discriminating between patients at a low and intermediate risk of TE complications.
Source: International Journal of Cardiology - November 21, 2011 Category: Cardiology Authors: E. Abu-Assi, F. Otero-Raviña, G. Allut Vidal, A. Coutado Méndez, L. Vaamonde Mosquera, M. Sánchez Loureiro, M.C. Caneda Villar, J.M. Fernández Villaverde, F.J. Maestro Saavedra, J.R. González-Juanatey, on behalf of Grupo Barbanza researchers Tags: Original Articles Source Type: research
Association of gender with morbidity and mortality after isolated coronary artery bypass grafting. A propensity score matched analysis
Abstract: Introduction: There is conflicting evidence about the impact of gender on outcomes after coronary artery bypass grafting (CABG).Methods: We performed a multivariate logistic regression and propensity score matched analyses in 13,115 patients (75% men) who underwent CABG between January 1, 1995 and December 31, 2009. The primary outcome was in-hospital mortality. Secondary outcomes included post-operative respiratory failure, stroke, myocardial infarction, sternal and leg wound infections, atrial fibrillation (AF), renal failure, need for postoperative intra-aortic balloon pump (IABP) support, and length of hospit...
Source: International Journal of Cardiology - January 12, 2012 Category: Cardiology Authors: Mahboob Alam, Vei-Vei Lee, McArthur A. Elayda, Saima A. Shahzad, Eric Y. Yang, Vijay Nambi, Hani Jneid, Wei Pan, Stephanie Coulter, James M. Wilson, Kodangudi B. Ramanathan, Christie M. Ballantyne, Salim S. Virani Tags: Original Articles Source Type: research
Atrial fibrillation: Profile and burden of an evolving epidemic in the 21st century
Abstract: Background: Atrial fibrillation (AF) represents an increasing public health challenge with profound social and economic implications.Methods: A comprehensive synthesis and review of the AF literature was performed. Overall, key findings from 182 studies were used to describe the indicative scope and impact of AF from an individual to population perspective.Results: There are many pathways to AF including advancing age, cardiovascular disease and increased levels of obesity/metabolic disorders. The reported population prevalence of AF ranges from 2.3%–3.4% and historical trends reflect increased AF incidence. Es...
Source: International Journal of Cardiology - February 4, 2013 Category: Cardiology Authors: Jocasta Ball, Melinda J. Carrington, John J.V. McMurray, Simon Stewart Tags: Reviews Source Type: research
Sleep disordered breathing is an independent risk factor for left atrial enlargement in patients with congestive heart failure
Left atrial enlargement (LAE) is an independent predictor of stroke and death . In patients with congestive heart failure (CHF) LAE has a high prevalence . Several conditions such as left ventricular remodeling, mitral regurgitation and atrial fibrillation (AF) are known to cause LAE in CHF patients. Lately attention has grown on the high prevalence of sleep disordered breathing (SDB) in CHF patients . SDB is also associated with poor prognosis in patients with CHF. We investigated 234 consecutive CHF patients to evaluate whether there is a relation between LAE and SDB.
Source: International Journal of Cardiology - November 19, 2012 Category: Cardiology Authors: Wanda Mäuser, Sarah Sandrock, Thomas Demming, Laura Kotzott, Hendrik Bonnemeier Tags: Letters to the Editor Source Type: research
Current presentation and management of 7148 patients with atrial fibrillation in cardiology and internal medicine hospital centers: The ATA AF study
Abstract: Background: Atrial fibrillation (AF) is associated with a high risk of stroke and mortality.Aims: To describe the difference in AF management of patients (pts) referred to Cardiology (CARD) or Internal Medicine (MED) units in Italy.Methods and results: From May to July 2010, 360 centers enrolled 7148 pts (54% in CARD and 46% in MED). Median age was 77years (IQR 70–83). Hypertension was the most prevalent associated condition, followed by hypercholesterolemia (28.9%), heart failure (27.7%) and diabetes (24.3%). MED pts were older, more frequently females and more often with comorbidities than CARD pts.In the 484...
Source: International Journal of Cardiology - August 13, 2012 Category: Cardiology Authors: Giuseppe Di Pasquale, Giovanni Mathieu, Aldo Pietro Maggioni, Gianna Fabbri, Donata Lucci, Giorgio Vescovo, Salvatore Pirelli, Francesco Chiarella, Marino Scherillo, Michele Massimo Gulizia, Gualberto Gussoni, Fabrizio Colombo, Domenico Panuccio, Carlo No Tags: Original Articles Source Type: research
Women with atrial fibrillation in Qatar with special reference to gender difference: Caution on the representativeness of non-Caucasian countries
Salam and colleagues reported the outcomes of treatment of women hospitalized with atrial fibrillation (AF) in Qatar, with special emphasis on the gender difference . Data of a total of 1417 women and 2432 men with cardiac illness from a hospital database were retrospectively analyzed. The results of the analysis revealed that the mean age of the women at admission for atrial fibrillation was 5 years older than that of the men, and that the prevalence of cardiovascular risk factors was higher in the women. However, there was no gender difference in the cardiovascular mortality or prevalence of stroke. Although there is a l...
Source: International Journal of Cardiology - March 28, 2013 Category: Cardiology Authors: Tomoyuki Kawada Tags: Letters to the Editor Source Type: research
The change in the atrial fibrillation type as a prognosis marker in a community study: Long-term data from AFBAR (Atrial Fibrillation in the BARbanza) study
Abstract: Background: The aim is to describe the prognosis role of the change in the atrial fibrillation (AF) type in an unselected population of patients with AF currently attending primary care in a single health-service area in Galicia, north-western Spain.Methods: AFBAR is a cohort study that was carried out by 35 primary care providers in 2008. Participants were followed up for a mean of 2.8±0.7years. 798 patients with the diagnosis of AF who presented at their clinics during a three-month period were recruited. Primary endpoint was mortality or hospital admission.Results: 778 patients (413 male) were analyzed; mean ...
Source: International Journal of Cardiology - March 1, 2013 Category: Cardiology Authors: Rafael Vidal-Perez, Fernando Otero-Raviña, Manuel Lado-López, Victorino Turrado-Turrado, Esperanza Rodríguez-Moldes, José L. Gómez-Vázquez, Concepción de Frutos-de Marcos, Paula de Blas-Abad, Ricardo Besada-Gesto, José Ramón Gonzalez-Juanatey, On Tags: Original Articles Source Type: research
