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Source: The American Journal of Cardiology
Condition: Atrial Fibrillation
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Total 336 results found since Jan 2013.
Sex Differences in Risk Factors for Incident Atrial Fibrillation (From the Reasons for Geographic And Racial Differences in Stroke (REGARDS) Study)
We examined whether the sex differences in atrial fibrillation (AF) is related to difference in risk factors leading to AF or due to a differential impact of the same risk factors in 11,806 participants (55.2 % women) from the REGARDS study. Incident AF was ascertained by electrocardiograms and medical history at a follow-up examination. Backwards elimination logistic regression was used to identify AF risk factors in men and women, separately. Over a median follow-up of 9.0 years, 588 (11.1%) men and 428 (6.6%) women (p-value
Source: The American Journal of Cardiology - February 9, 2019 Category: Cardiology Authors: Abhishek Bose, Wesley T. O'Neal, Chengyi Wu, Leslie A. McClure, Suzanne E. Judd, Virginia J. Howard, George Howard, Elsayed Z. Soliman Source Type: research
Thoracoscopic Left Atrial Appendage Occlusion for Stroke Prevention Compared with Long-Term Warfarin Therapy in Patients With Nonvalvular Atrial Fibrillation
In their recent paper, Fu et al. conclude that thoracoscopic left atrial appendage (LAA) occlusion is superior to warfarin for a composite outcome of stroke, systemic embolism and mortality.1 We suggest considering their results with caution.
Source: The American Journal of Cardiology - February 8, 2019 Category: Cardiology Authors: Sophie Weiwei Gao, Emilie Prudence Belley-C ôté, Kevin John Um, Richard Paul Whitlock Tags: Reader's Comments Source Type: research
Relation of Left Atrial Appendage Morphology Determined by Computed Tomography to Prior Stroke or to Increased Risk of Stroke in Patients With Atrial Fibrillation
This study aimed to assess inter-observer and intra-observer agreements in LAA morphology and its real value in stroke prediction. A total of 2264 atrial fibrillation (AF) patients who underwent computed tomography (CT) to explore the LAA anatomy were enrolled.
Source: The American Journal of Cardiology - January 23, 2019 Category: Cardiology Authors: Lingmin Wu, Erpeng Liang, Siyang Fan, Lihui Zheng, Zhongpeng Du, Shangyu Liu, Feng Hu, Xiaohan Fan, Gang Chen, Ligang Ding, Yan Yao Source Type: research
Incidence, Predictors, Management, and Clinical Significance of New-Onset Atrial Fibrillation After Transcatheter Aortic Valve Implantation
There is limited information on the incidence, management, and prognostic impact of new-onset atrial fibrillation (NOAF) following transcatheter aortic valve implantation (TAVI) for severe aortic valve stenosis (AS). In the prospective ASAN-TAVI registry, we evaluated a total of 347 consecutive patients who underwent TAVI between March 2010 and August 2017. The primary endpoint was a composite of stroke or systemic embolism at 12 months. The study subjects were categorized into 3 groups; pre-existing AF (50 patients), NOAF (31 patients), and non-AF (266 patients) group.
Source: The American Journal of Cardiology - January 4, 2019 Category: Cardiology Authors: Yong-Hoon Yoon, Jung-Min Ahn, Do-Yoon Kang, Euihong Ko, Pil Hyung Lee, Seung-Whan Lee, Ho Jin Kim, Joon Bum Kim, Suk Jung Choo, Duk-Woo Park, Seung-Jung Park Source Type: research
Meta-analysis of Stroke and Bleeding Risk in Patients with Various Atrial Fibrillation Patterns Receiving Oral Anticoagulants
Oral anticoagulation therapy (OAT) is a mainstay for stroke prevention in atrial fibrillation (AF) patients. However, whether the risks of stroke/systemic embolic events (SEE) and bleeding events are affected by the type, duration, and frequency of AF in patients receiving OAT has been previously debated. We aimed to determine the risk of stroke/SEE and bleeding events associated with paroxysmal AF compared to persistent or permanent AF among patients who received OAT. Comprehensive literature searches of the Cochrane Library, PubMed/MEDLINE, and EMBASE databases were conducted from inception to July 2018.
Source: The American Journal of Cardiology - December 19, 2018 Category: Cardiology Authors: Weifang Zhang, Youwen Xiong, Lingling Yu, Aizhen Xiong, Huihui Bao, Xiaoshu Cheng Source Type: research
Relation of Race, Apparent Disability, and Stroke Risk With Warfarin Prescribing for Atrial Fibrillation in Patients Receiving Maintenance Hemodialysis
We examined patterns of warfarin use, and associated factors, after AF diagnosis. This retrospective cohort analysis studied US Medicare patients receiving maintenance dialysis January 1, 2008-June 30, 2010. Demographics, comorbidity, and a durable medical equipment claims-based disability proxy score predicted warfarin prescription after AF diagnosis. The analysis included 8964 patients with non-valvular AF.
Source: The American Journal of Cardiology - November 24, 2018 Category: Cardiology Authors: James B. Wetmore, Yi Peng, David T. Gilbertson, Jiannong Liu Source Type: research
Impact of Body Mass Index on Outcomes in the Edoxaban Versus Warfarin Therapy Groups in Patients Undergoing Cardioversion of Atrial Fibrillation (From ENSURE-AF)
In the EdoxabaN versus warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study (NCT 02072434), edoxaban showed similar efficacy and safety vs enoxaparin –warfarin in patients undergoing electrical cardioversion of nonvalvular atrial fibrillation. In this ancillary analysis, we compared the primary efficacy (composite of stroke, systemic embolic event, myocardial infarction, and cardiovascular [CV] death, overall study period) and safety (composite of major and clinically relevant nonmajor [CRNM] bleeding, on-treatment) endpoints in relation to body mass index (BMI;
Source: The American Journal of Cardiology - November 24, 2018 Category: Cardiology Authors: Gregory Y.H. Lip, Jose L. Merino, Maciej Banach, Joris R. de Groot, Lars S. Maier, Sakis Themistoclakis, Giuseppe Boriani, James Jin, Michael Melino, Shannon M. Winters, Andreas Goette Source Type: research
Relation of the CHA2DS2-VASc Score to Risk of Thrombotic and Embolic Stroke in Community-Dwelling Individuals Without Atrial Fibrillation (From The Atherosclerosis Risk in Communities ARIC Study)
Recent hospital-based cohort studies found the CHA2DS2-VASc score to be associated with ischemic stroke in individuals without atrial fibrillation (AF). Our aim was to determine the distribution of embolic and thrombotic strokes and association with the CHA2DS2-VASc score, among community-dwelling individuals without AF. We included participants from the Atherosclerosis Risk in Communities (ARIC) Study who attended visit 4 (1996-98) and had no prior AF, stroke, or anticoagulant use (n=10,671). During follow-up through 2008, incident AF cases (n=760) and participants who started warfarin were censored.
Source: The American Journal of Cardiology - November 6, 2018 Category: Cardiology Authors: Ryan J. Koene, M. Chadi Alraies, Faye L. Norby, Elsayed Z. Soliman, Ankit Maheshwari, Gregory Y.H. Lip, Alvaro Alonso, Lin Y. Chen Source Type: research
Comparison of Frequency of Ischemic Stroke in Patients With Versus Without Coronary Heart Disease and Without Atrial Fibrillation
We examined ischemic stroke risk in patients without atrial fibrillation who underwent coronary angiography between 2004 and 2012. Patients were stratified according to presence or absence of CAD and further stratified by extent of CAD (0 vessel disease [VD], 1 VD, 2 VD, 3 VD, and diffuse VD).
Source: The American Journal of Cardiology - October 30, 2018 Category: Cardiology Authors: Kevin Kris Warnakula Olesen, Kamilla Steensig, Morten Madsen, Troels Thim, Lisette Okkels Jensen, Bent Raungaard, John Eikelboom, Steen Dalby Kristensen, Hans Erik B øtker, Michael Maeng Source Type: research
Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20-years (from the Atherosclerosis Risk in Communities ARIC Study)
Resting heart rate (RHR) is independently associated with cardiovascular disease (CVD) risk. We determined whether RHR, measured in mid-life, is also associated with cognitive decline. We studied 13,720 middle-aged white and black ARIC participants without a prior history of stroke or atrial fibrillation. RHR was obtained from a 12-lead resting electrocardiogram at the baseline visit (1990-1992) and categorized into groups as
Source: The American Journal of Cardiology - October 20, 2018 Category: Cardiology Authors: Stephanie Wang, Oluwaseun E. Fashanu, Di Zhao, Eliseo Guallar, Rebecca F. Gottesman, Andrea L.C. Schneider, John W. McEvoy, Faye L. Norby, Amer I. Aladin, Alvaro Alonso, Erin D. Michos Source Type: research
Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20 Years (from the Atherosclerosis Risk in Communities ARIC Study)
Resting heart rate (RHR) is independently associated with cardiovascular disease (CVD) risk. We determined whether RHR, measured in mid-life, is also associated with cognitive decline. We studied 13,720 middle-aged white and black ARIC participants without a history of stroke or atrial fibrillation. RHR was obtained from a 12-lead resting electrocardiogram at the baseline visit (1990 to 1992) and categorized into groups as
Source: The American Journal of Cardiology - October 20, 2018 Category: Cardiology Authors: Stephanie Wang, Oluwaseun E. Fashanu, Di Zhao, Eliseo Guallar, Rebecca F. Gottesman, Andrea L.C. Schneider, John W. McEvoy, Faye L. Norby, Amer I. Aladin, Alvaro Alonso, Erin D. Michos Source Type: research
Prevalence and Resolution of Left Atrial Thrombus in Patients With Nonvalvular Atrial Fibrillation and Flutter With Oral Anticoagulation
This study sought to establish 1) the prevalence of LAA thrombus 2) the prevalence of LAA thrombus despite antithrombotic therapy, 3) the rate of persistence of LAA thrombus despite appropriate anticoagulant prescriptions, and 4) determinants of LAA thrombus persistence.
Source: The American Journal of Cardiology - September 26, 2018 Category: Cardiology Authors: Adam D Niku, Takahiro Shiota, Robert J Siegel, Florian Rader Source Type: research
Thoracoscopic Left Atrial Appendage Occlusion for Stroke Prevention Compared with Long-Term Warfarin Therapy in Patients With Nonvalvular Atrial Fibrillation
Thoracoscopic left atrial appendage (LAA) occlusion is an alternative treatment for stroke prevention in patients with atrial fibrillation. Prospective study comparing thoracoscopic LAA occlusion and warfarin therapy is still lacking. The goal of this prospective cohort study was to assess the safety and efficacy of thoracoscopic LAA occlusion for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF) compared with long-term warfarin therapy. 492 NVAF Patients were enrolled. 257 patients were treated with thoracoscopic LAA occlusion and 235 with long-term warfarin therapy.
Source: The American Journal of Cardiology - September 26, 2018 Category: Cardiology Authors: Mingjie Fu, Zheng Qin, Shuai Zheng, Yueping Li, Shiwei Yang, Yingxin Zhao, Chengping Hu, Kuo Zhou, Yujie Zhou, Xu Meng Source Type: research
Underuse of oral anticoagulants in patients with ischemic stroke and atrial fibrillation in China
Anticoagulant therapy is an effective stroke prevention measure for people with atrial fibrillation (AF) who are at high risk of ischemic stroke. However, it is reported that oral anticoagulants (OACs) are generally underused in clinical practice. A better awareness of current usage of anticoagulant therapy would enable prevention of stroke secondary to AF. Therefore, we determined the nationwide prevalence of AF and the frequency of OACs use among patients with ischemic stroke in China. Based on the China National Stroke Screening Survey (CNSSS), a representative nationwide sample of 1,252,703 adults over 40 years old dur...
Source: The American Journal of Cardiology - September 13, 2018 Category: Cardiology Authors: Jian Guo, Tianjia Guan, Siyuan Fan, Baohua Chao, Longde Wang, Yuanli Liu Source Type: research
Extended Cardiac Monitoring in Patients with Severe Sleep Apnea and no History of Atrial Fibrillation (The Reveal XT-SA Study)
Atrial fibrillation (AF) is a risk factor for ischemic stroke and reported to be associated with severe obstructive sleep apnea (OSA). The aim of this study was to determine the occurrence of newly detected AF in patients with severe OSA and no prior history of AF. Prospective observational study included patients with severe OSA (Apnea-Hypopnea Index (AHI) ≥ 30) and no history of AF. Primary outcome was detection of AF lasting ≥10 s. Patients were subjected to 2 24-hour Holter monitors, and if no AF was detected, implanted with a Medtronic Reveal XT implantable loop recorder (ILR).
Source: The American Journal of Cardiology - September 7, 2018 Category: Cardiology Authors: Cynthia Yeung, Doran Drew, Sharlene Hammond, Wilma M. Hopman, Damian Redfearn, Christopher Simpson, Hoshiar Abdollah, Adrian Baranchuk Source Type: research
