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Source: The American Journal of Cardiology
Condition: Atrial Fibrillation
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Total 336 results found since Jan 2013.
Financial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database)
The objective of this study was to evaluate the financial implications and the impact of pre-existing atrial fibrillation (AF) on in-hospital outcomes in patients who underwent transcatheter aortic valve implantation (TAVI) using the Nationwide Inpatient Sample (NIS) database. We identified patients who underwent TAVI from 2011 to 2014. The primary end point was the effect of pre-existing AF on in-hospital mortality. Secondary end points included periprocedural cardiac complications, stroke, and hemorrhage requiring transfusion.
Source: The American Journal of Cardiology - March 14, 2018 Category: Cardiology Authors: Hossam Abubakar, Ahmed S. Yassin, Emmanuel Akintoye, Khalid Bakhit, Mohit Pahuja, Mohamed Shokr, Randy Lieberman, Luis Afonso Source Type: research
Feasibility of Left Atrial Appendage Occlusion for Left Atrial Appendage Thrombus in Patients With Persistent Atrial Fibrillation
This study sought to investigate the safety of percutaneous left atrial appendage (LAA) occlusion for stroke prevention in patients with nonvalvular atrial fibrillation who have LAA thrombus. From October 2010 to October 2016, LAA occlusions were performed in facilities within a Korean multicenter registry in patients without (n = 132) or with (n = 10) LAA thrombus (detected during preprocedural assessments). The incidences of periprocedural complications, including stroke, pericardial tamponade, major bleeding, and device embolization, were assessed and compared between the groups.
Source: The American Journal of Cardiology - March 14, 2018 Category: Cardiology Authors: Oh-Hyun Lee, Jung-Sun Kim, Hui-Nam Pak, Geu-Ru Hong, Chi Young Shim, Jae-Sun Uhm, In-Jeong Cho, Boyoung Joung, Cheol-Woong Yu, Hyun-Jong Lee, Woong-Chol Kang, Eun-Seok Shin, Rak-kyeong Choi, Do-Sun Lim, Yangsoo Jang Source Type: research
Feasibility of Left Atrial Appendage Occlusion for Left Atrial Appendage Thrombus in Patients with Persistent Atrial Fibrillation
This study sought to investigate the safety of percutaneous left atrial appendage (LAA) occlusion for stroke prevention in patients of nonvalvular atrial fibrillation with LAA thrombus. From October 2010 to October 2016, LAA occlusions were performed in facilities within a Korean multicenter registry in patients without (n = 132) or with (n = 10) LAA thrombus (detected during preprocedural assessments). The incidences of periprocedural complications, including stroke, pericardial tamponade, major bleeding, and device embolization, were assessed and compared between the groups.
Source: The American Journal of Cardiology - March 14, 2018 Category: Cardiology Authors: Oh-Hyun Lee, Jung-Sun Kim, Hui-Nam Pak, Geu-Ru Hong, Chi Young Shim, Jae-Sun Uhm, In-Jeong Cho, Boyoung Joung, Cheol-Woong Yu, Hyun-Jong Lee, Woong-Chol Kang, Eun-Seok Shin, Rak-kyeong Choi, Do-Sun Lim, Yangsoo Jang Source Type: research
Real-Time Pathophysiologic Correlates of Left Atrial Appendage Thrombus in Patients Who Underwent Transesophageal-Guided Electrical Cardioversion for Atrial Fibrillation
Although current guidelines advocate using the CHA2DS2-VASc score to assess the risk of stroke in patients with atrial fibrillation (AF), compared with transesophageal echocardiography (TEE), its ability to predict left atrial appendage thrombus (LAAT) is limited. We studied 3,324 consecutive patients with sustained AF from our prospective registry of patients who underwent first-time TEE-guided electrical cardioversion (ECV) from May 2000 through March 2012. The association of CHA2DS2-VASc score or TEE risk factors with the occurrence of LAAT was analyzed.
Source: The American Journal of Cardiology - March 13, 2018 Category: Cardiology Authors: Rowlens M. Melduni, Bernard J. Gersh, Waldemar E. Wysokinski, Naser M. Ammash, Paul A. Friedman, David O. Hodge, Krishnaswamy Chandrasekaran, Jae K. Oh, Hon-Chi Lee Source Type: research
Real-Time Pathophysiologic Correlates of Left Atrial Appendage Thrombus in Patients Undergoing Transesophageal-Guided Electrical Cardioversion for Atrial Fibrillation
Although current guidelines advocate using the CHA2DS2-VASc score to assess the risk of stroke in patients with atrial fibrillation (AF), compared with transesophageal echocardiographic (TEE), its ability to predict left atrial appendage thrombus (LAAT) is limited. We studied 3,324 consecutive patients with sustained AF from our prospective registry of patients undergoing first-time TEE-guided electrical cardioversion (ECV) from May 2000 through March 2012. The association of CHA2DS2-VASc score or TEE risk factors with the occurrence of LAAT was analyzed.
Source: The American Journal of Cardiology - March 13, 2018 Category: Cardiology Authors: Rowlens M. Melduni, Bernard J. Gersh, Waldemar E. Wysokinski, Naser M. Ammash, Paul A. Friedman, David O. Hodge, Krishnaswamy Chandrasekaran, Jae K. Oh, Hon-Chi Lee Source Type: research
Patent Foramen Ovale Closure - When Number Needed to Treat and Number Needed to Harm Do Not Tell the Whole Story
We read with interest the thorough meta-analysis of Ando at al. (1) comparing patent foramen ovale (PFO) closure against medical therapy. The authors showed that PFO closure reduced the risk of recurrent stroke by 58% with a number needed to treat (NNT) of 38. PFO closure plus medical therapy, however, conferred a significant increase in risk of newly detected atrial fibrillation (AF) with a number needed to harm (NNH) of 29. With 4.3%, the prevalence of newly detected AF after PFO closure was similar to the one of 3.7% (95% CI, 2.9% –4.6%) in a recent large retrospective cohort study of 1887 patients (2).
Source: The American Journal of Cardiology - February 13, 2018 Category: Cardiology Authors: Franz H. Messerli, Bernhard Meier Source Type: research
Stroke and Cardiovascular Events After Ablation or Antiarrhythmic Drugs for Treatment of Patients With Atrial Fibrillation
Catheter ablation and antiarrhythmic drugs (AADs) are the most common rhythm-control strategies for atrial fibrillation (AF). Data comparing the rate of stroke and cardiovascular events between the treatment strategies are limited. Therefore, this observational study uses claims data to compare rate of cardiovascular hospitalization and stroke for patients with AF treated with ablation or AADs. Patients in the MarketScan dataset with AF between January 2010 and December 2014 were categorized in the ablation group if an atrial catheter ablation was performed, or in the AAD group if a relevant AAD was prescribed for AF but n...
Source: The American Journal of Cardiology - February 12, 2018 Category: Cardiology Authors: Moussa Mansour, E. Kevin Heist, Rahul Agarwal, T. Jared Bunch, Edward Karst, Jeremy N. Ruskin, Srijoy Mahapatra Source Type: research
Usefulness of the CHA2DS2-VASc and HAS-BLED Scores in Predicting the Risk of Stroke Versus Intracranial Bleeding in Patients With Atrial Fibrillation (from the FibStroke Study)
CHA2DS2-VASc and HAS-BLED scores stratify the risk of thromboembolic and bleeding events respectively in patients with atrial fibrillation. There is only little information on how they differentiate which of the 2 clinically most important complications (ischemic stroke [IS] or an intracranial bleeding [IB]) the patient is more prone to suffer. We evaluated both scores in patients with either of these major complications. The FibStroke Study collected data on all patients with atrial fibrillation with either an IS or an IB event between 2003 and 2012 in 4 Finnish hospital districts.
Source: The American Journal of Cardiology - February 12, 2018 Category: Cardiology Authors: Samuli Jaakkola, Tuomas O. Kiviniemi, Ilpo Nuotio, Juha Hartikainen, Pirjo Mustonen, Antti Palom äki, Jussi Jaakkola, Antti Ylitalo, Päivi Hartikainen, K.E. Juhani Airaksinen Source Type: research
Stroke and Cardiovascular Events after Ablation or Anti-Arrhythmic Drugs for Treatment of Patients with Atrial Fibrillation
Catheter ablation and anti-arrhythmic drugs (AADs) are the most common rhythm-control strategies for atrial fibrillation (AF). Data comparing the rate of stroke and cardiovascular events between the treatment strategies are limited. Therefore, this observational study uses claims data to compare rate of cardiovascular hospitalization and stroke for patients with AF treated with ablation or AADs. Patients in the MarketScan dataset with AF between January 2010 and December 2014 were categorized in the ablation group if an atrial catheter ablation was performed, or in the AAD group if a relevant AAD was prescribed for AF but ...
Source: The American Journal of Cardiology - February 12, 2018 Category: Cardiology Authors: Moussa Mansour, E. Kevin Heist, Rahul Agarwal, T. Jared Bunch, Edward Karst, Jeremy N. Ruskin, Srijoy Mahapatra Source Type: research
Usefulness of the CHA2DS2-VASc and HAS-BLED Scores in Predicting the Risk of Stroke Versus Intracranial Bleeding in Patients with Atrial Fibrillation (From the FibStroke Study)
CHA2DS2-VASc and HAS-BLED scores stratify the risk of thromboembolic and bleeding events respectively in patients with atrial fibrillation (AF). There is only little information on how they differentiate which of the 2 clinically most important complications (ischemic stroke, IS or an intracranial bleeding, IB) the patient is more prone to suffer. We evaluated both scores in patients suffering either of these major complications. The FibStroke Study collected data on all patients with AF suffering either an ischemic stroke or an intracranial bleeding event between 2003-2012 in 4 Finnish hospital districts.
Source: The American Journal of Cardiology - February 12, 2018 Category: Cardiology Authors: Samuli Jaakkola, Tuomas O. Kiviniemi, Ilpo Nuotio, Juha Hartikainen, Pirjo Mustonen, Antti Palom äki, Jussi Jaakkola, Antti Ylitalo, Päivi Hartikainen, K.E. Juhani Airaksinen Source Type: research
Anticoagulant Agents for Atrial Fibrillation in Cancer Patients
In a recent article in the journal, Patell et al1 found CHADS2 (congestive heart failure, hypertension, age ≥ 75, diabetes mellitus, prior stroke/transient ischemic attack/thromboembolism) and CHA2DS2VASC (congestive heart failure, hypertension, age ≥ 75, diabetes mellitus, prior stroke/transient ischemic attack/thromboembolism, vascular disease, age 65-74, sex category [i.e., female]) to predict risk of ischemic stroke in cancer patients with baseline atrial fibrillation (AF). Although only 36% of patients received anticoagulant therapy, the risk of stroke generally appeared to be lower than in cancer-free individuals.
Source: The American Journal of Cardiology - February 3, 2018 Category: Cardiology Authors: Marc Sorigue, Edurne Sarrate, Mireia Franch-Sarto, Mireia Santos-Gomez, Elisa Orna Source Type: research
Meta-Analysis Comparing Patent Foramen Ovale Closure Versus Medical Therapy to Prevent Recurrent Stroke
It is unknown if closure of a patent foramen ovale (PFO) plus medical therapy (MT; antiplatelet or anticoagulation) is superior to MT alone to prevent recurrent cryptogenic stroke. We performed a meta-analysis of randomized controlled trials (RCT) that compared PFO closure plus MT to MT alone in patients with cryptogenic stroke. The efficacy endpoints were recurrent stroke, transient ischemia attack (TIA), and death. The safety endpoints were major bleeding and newly-detected atrial fibrillation (AF).
Source: The American Journal of Cardiology - December 11, 2017 Category: Cardiology Authors: Tomo Ando, Anthony A. Holmes, Mohit Pahuja, Arshad Javed, Alenxandros Briasoulis, Tesfaye Telila, Hisato Takagi, Theodore Schreiber, Luis Afonso, Cindy L. Grines, Sripal Bangalore Source Type: research
