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Source: The American Journal of Cardiology
Condition: Atrial Fibrillation
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Total 336 results found since Jan 2013.
Assessment of Device Related Thrombus and Associated Clinical Outcomes with the WATCHMAN Left Atrial Appendage Closure Device for Embolic Protection in Patients with Atrial Fibrillation (From the PROTECT-AF Trial)
Left atrial appendage (LAA) closure with the WATCHMAN device is an alternative to anticoagulation for stroke prevention in selected patients with atrial fibrillation (AF). LA device related thrombus (DRT) is poorly defined and understood. We aimed to 1) develop consensus echocardiographic diagnostic criteria for DRT 2) estimate the incidence of DRT and 3) determine clinical event rates in patients with DRT. In Phase 1 (Training), a training manual was developed and reviewed by 3 echocardiographers with LAA closure device experience.
Source: The American Journal of Cardiology - February 1, 2016 Category: Cardiology Authors: Michael L. Main, Dali Fan, Vivek Y. Reddy, David R. Holmes, Nicole T. Gordon, Tina R. Coggins, John A. House, Lawrence Liao, Dawn Rabineau, George G. Latus, Kenneth C. Huber, Horst Sievert, Richard F. Wright, Shephal K. Doshi, Pamela S. Douglas Source Type: research
Anticoagulation, CHADSVASc Score, and Thromboembolic Risk of Cardioversion of Acute Atrial Fibrillation (from the FinCV Study)
The efficacy of the anticoagulation in preventing thromboembolic complications (TEC) and the usefulness of the CHA2DS2VASc score for assessing stroke risk during cardioversion of acute atrial fibrillation (AF) are unclear. Thus, our objectives were to assess the ability of the CHA2DS2VASc score to predict TEC and to evaluate the efficacy of anticoagulation in the prevention of TEC in Finnish CardioVersion (FinCV) study. The FinCV is a retrospective, multicenter study of 3,143 patients, who underwent 7,660 cardioversions for acute AF.
Source: The American Journal of Cardiology - January 28, 2016 Category: Cardiology Authors: Toni Grönberg, Juha E.K. Hartikainen, Ilpo Nuotio, Fausto Biancari, Antti Ylitalo, K.E. Juhani Airaksinen Tags: Arrhythmias and Conduction Source Type: research
Usefulness of the CHADSVAS Score to Predict Adverse Outcomes in Patients having Percutaneous Coronary Intervention
The application of the CHA2DS2-VASC score as a novel risk stratification tool for predicting outcome in clinical applications other than atrial fibrillation (AF) and stroke prevention has been previously examined. However its usefulness in a population of patients with coronary artery disease following percutaneous coronary intervention (PCI) has not been explored. We investigated 12,785 consecutive patients who underwent PCI in a tertiary medical center between 4/2004 and 8/2014 (mean follow up 6.5 years) and computed the CHA2DS2-VASC score on their index PCI.
Source: The American Journal of Cardiology - February 16, 2016 Category: Cardiology Authors: Katia Orvin, Tamir Bental, Abid Assali, Eli Israel Lev, Hana Vaknin-Assa, Ran Kornowski Source Type: research
Usefulness of the CHA2DS2VASC Score to Predict Adverse Outcomes in Patients having Percutaneous Coronary Intervention
The application of the CHA2DS2-VASC score as a novel risk stratification tool for predicting outcome in clinical applications other than atrial fibrillation (AF) and stroke prevention has been previously examined. However its usefulness in a population of patients with coronary artery disease following percutaneous coronary intervention (PCI) has not been explored. We investigated 12,785 consecutive patients who underwent PCI in a tertiary medical center between 4/2004 and 8/2014 (mean follow up 6.5 years) and computed the CHA2DS2-VASC score on their index PCI.
Source: The American Journal of Cardiology - February 16, 2016 Category: Cardiology Authors: Katia Orvin, Tamir Bental, Abid Assali, Eli Israel Lev, Hana Vaknin-Assa, Ran Kornowski Source Type: research
Assessment of Device-Related Thrombus and Associated Clinical Outcomes With the WATCHMAN Left Atrial Appendage Closure Device for Embolic Protection in Patients With Atrial Fibrillation (from the PROTECT-AF Trial)
Left atrial appendage closure with the WATCHMAN device is an alternative to anticoagulation for stroke prevention in selected patients with atrial fibrillation (AF). LA device-related thrombus (DRT) is poorly defined and understood. We aimed to (1) develop consensus echocardiographic diagnostic criteria for DRT; (2) estimate the incidence of DRT; and (3) determine clinical event rates in patients with DRT. In phase 1 (training), a training manual was developed and reviewed by 3 echocardiographers with left atrial appendage closure device experience.
Source: The American Journal of Cardiology - February 1, 2016 Category: Cardiology Authors: Michael L. Main, Dali Fan, Vivek Y. Reddy, David R. Holmes, Nicole T. Gordon, Tina R. Coggins, John A. House, Lawrence Liao, Dawn Rabineau, George G. Latus, Kenneth C. Huber, Horst Sievert, Richard F. Wright, Shephal K. Doshi, Pamela S. Douglas Tags: Arrhythmias and Conduction Disturbances Source Type: research
Anticoagulation, CHA2DS2VASc Score, and Thromboembolic Risk of Cardioversion of Acute Atrial Fibrillation (from the FinCV Study)
The efficacy of the anticoagulation in preventing thromboembolic complications (TEC) and the usefulness of the CHA2DS2VASc score for assessing stroke risk during cardioversion of acute atrial fibrillation (AF) are unclear. Thus, our objectives were to assess the ability of the CHA2DS2VASc score to predict TEC and to evaluate the efficacy of anticoagulation in the prevention of TEC in Finnish CardioVersion (FinCV) study. The FinCV is a retrospective, multicenter study of 3,143 patients, who underwent 7,660 cardioversions for acute AF.
Source: The American Journal of Cardiology - January 28, 2016 Category: Cardiology Authors: Toni Grönberg, Juha E.K. Hartikainen, Ilpo Nuotio, Fausto Biancari, Antti Ylitalo, K.E. Juhani Airaksinen Tags: Arrhythmias and Conduction Source Type: research
Usefulness of the CHA2DS2-VASC Score to Predict Adverse Outcomes in Patients Having Percutaneous Coronary Intervention
The application of the CHA2DS2-VASC score as a novel risk stratification tool for predicting outcome in clinical applications other than atrial fibrillation and stroke prevention has been previously examined. However, its usefulness in a population of patients with coronary artery disease after percutaneous coronary intervention (PCI) has not been explored. We investigated 12,785 consecutive patients who underwent PCI in a tertiary medical center from April 2004 to August 2014 (mean follow-up 6.5 years) and computed the CHA2DS2-VASC score on their index PCI.
Source: The American Journal of Cardiology - February 16, 2016 Category: Cardiology Authors: Katia Orvin, Tamir Bental, Abid Assali, Eli Israel Lev, Hana Vaknin-Assa, Ran Kornowski Tags: Coronary Artery Disease Source Type: research
Relation of Non-Valvular Atrial Fibrillation to Body Mass Index (From the SPORTIF Trials)
Obesity is well-established as a major cardiovascular (CV) risk factor. Obesity confers a higher risk for developing atrial fibrillation (AF), but the relation between obesity and established non-valvular AF (NVAF) for stroke and all-cause death is still unclear. To ascertain the prevalence of overweight and obesity in NVAF patients, their influence on adverse events and the relation with anticoagulation control we performed this post-hoc analysis of the pooled SPORTIF III and V datasets. For this study, we analysed all patients assigned to the warfarin arm with data on body mass index(BMI).
Source: The American Journal of Cardiology - April 19, 2016 Category: Cardiology Authors: Marco Proietti, Deirdre A. Lane, Gregory Y.H. Lip Source Type: research
Long-Term Population-Based Cerebral Ischemic Event and Cognitive Outcomes of Direct Oral Anticoagulants Compared to Warfarin among Long-Term Anticoagulated Patients for Atrial Fibrillation
Direct oral anticoagulants (DOACs) have been used in clinical practice in the US for the last 4-6 years. While DOACs may be an attractive alternative to warfarin among many patients, long-term outcomes of use of these medications are unknown. We performed a propensity-matched analysis to report patient important outcomes of death, stroke/TIA, bleeding, major bleeding and dementia among patients taking a DOAC or warfarin. Patients receiving long-term anticoagulation between June 2010-December 2014 for thromboembolism prevention with either warfarin or a DOAC were matched 1:1 by index date and propensity score.
Source: The American Journal of Cardiology - May 4, 2016 Category: Cardiology Authors: Victoria Jacobs, Heidi T. May, Tami L. Bair, Brian G. Crandall, Michael J. Cutler, John D. Day, Charles Mallender, Jeffrey S. Osborn, Scott M. Stevens, J. Peter Weiss, Scott C. Woller, T. Jared Bunch Source Type: research
Prognostic Implications of Left Ventricular Scar Determined by Late Gadolinium Enhanced Cardiac Magnetic Resonance in Patients with Atrial Fibrillation
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease (CAD) and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with CAD, prior myocardial infarction (MI), or hypertrophic or dilated cardiomyopathy were excluded. The endpoints of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death,...
Source: The American Journal of Cardiology - July 17, 2016 Category: Cardiology Authors: Promporn Suksaranjit, Christopher J. McGann, Nazem Akoum, Joseph Biskupiak, Gregory J. Stoddard, Eugene G. Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F. Marrouche, Brent D. Wilson Source Type: research
Evaluation of 5 Prognostic Scores for Prediction of Stroke, Thromboembolic and Coronary Events, All-Cause Mortality, and Major Adverse Cardiac Events in Patients With Atrial Fibrillation and Coronary Stenting
Management of antithrombotic therapy in patients with atrial fibrillation (AF) and coronary stenting remains challenging, and there is a need for efficient tools to predict their risk of different types of cardiovascular events and death. Several scores exist such as the CHA2DS2-VASc score, the Global Registry of Acute Coronary Events (GRACE) score, the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score, the Anatomical and Clinical Syntax II Score and the Reduction of Atherothrombosis for Continued Health score.
Source: The American Journal of Cardiology - June 13, 2016 Category: Cardiology Authors: Laurent Fauchier, Coralie Lecoq, Yann Ancedy, Karim Stamboul, Christophe Saint Etienne, Fabrice Ivanes, Denis Angoulvant, Dominique Babuty, Yves Cottin, Gregory Y.H. Lip Tags: Arrhythmias and Conduction Source Type: research
Prognostic Implications of Left Ventricular Scar Determined by Late Gadolinium Enhanced Cardiac Magnetic Resonance in Patients with Atrial Fibrillation
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease (CAD) and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with CAD, prior myocardial infarction (MI), or hypertrophic or dilated cardiomyopathy were excluded. The endpoints of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death,...
Source: The American Journal of Cardiology - July 17, 2016 Category: Cardiology Authors: Promporn Suksaranjit, Christopher J. McGann, Nazem Akoum, Joseph Biskupiak, Gregory J. Stoddard, Eugene G. Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F. Marrouche, Brent D. Wilson Source Type: research
Evaluation of 5 Prognostic Scores for Prediction of Stroke, Thromboembolic and Coronary Events, All-Cause Mortality, and Major Adverse Cardiac Events in Patients With Atrial Fibrillation and Coronary Stenting
Management of antithrombotic therapy in patients with atrial fibrillation (AF) and coronary stenting remains challenging, and there is a need for efficient tools to predict their risk of different types of cardiovascular events and death. Several scores exist such as the CHA2DS2-VASc score, the Global Registry of Acute Coronary Events (GRACE) score, the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score, the Anatomical and Clinical Syntax II Score and the Reduction of Atherothrombosis for Continued Health score.
Source: The American Journal of Cardiology - June 13, 2016 Category: Cardiology Authors: Laurent Fauchier, Coralie Lecoq, Yann Ancedy, Karim Stamboul, Christophe Saint Etienne, Fabrice Ivanes, Denis Angoulvant, Dominique Babuty, Yves Cottin, Gregory Y.H. Lip Tags: Arrhythmias and Conduction Source Type: research
Usefulness of Atrial Fibrillation as a Marker for Adverse Cardiovascular Outcomes in Both Primary and Secondary Prevention in Patients with Implantable Cardioverter-Defibrillators
Whether the risk factors for cardiovascular (CV) outcomes are different in primary vs. secondary prevention implantable cardioverter-defibrillator (ICD) patients is unclear. We sought to identify predictors of CV outcomes in ICD recipients for primary (G1) vs. secondary prevention (G2). Consecutive patients who had ICD implanted during August 2005 –December 2009 were included. The primary outcome was a composite of appropriate shock, acute coronary syndrome, ischemic stroke, coronary revascularization, heart failure exacerbation, CV hospitalization, or all-cause death.
Source: The American Journal of Cardiology - August 22, 2016 Category: Cardiology Authors: Ian CY. Chang, Yusuf Agawami, Erin Austin, Wayne O. Adkisson, Henri Roukoz, Lisa N. von Wald, Scott Sakaguchi, David G. Benditt, Lin Y. Chen Source Type: research
Comparative Efficacy of Clinical Events Prevention of Five Anticoagulants in Patients with Atrial Fibrillation (A Network Meta-Analysis)
This study is designed to assess the relative efficacy of several clinical events prevention anticoagulants in patients with AF. Conventional pair-wised meta-analysis was performed with fixed-effect model initially then network meta-analysis (NMA) was performed with random-effects model within results illustrated by cumulative odds ratios (ORs) and corresponding 95% credible interval (CrI).
Source: The American Journal of Cardiology - November 15, 2016 Category: Cardiology Authors: Lin Guo, Shuangzhan Li, Pin Wang, Xiaoming Zhong, Yan Hong Source Type: research
