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Source: Atherosclerosis
Condition: Atrial Fibrillation
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Total 150 results found since Jan 2013.
A causal relationship between irritability and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: Our findings support the first genetic evidence of the causality of genetically predicted irritability with the risk of developing into CVDs. Our results deliver a viewpoint that more early active interventions to manage an individual's anger and related unhealthy lifestyle habits are needed to prevent the occurrence of adverse cardiovascular events.PMID:37324625 | PMC:PMC10267866 | DOI:10.3389/fcvm.2023.1174329
Source: Atherosclerosis - June 16, 2023 Category: Cardiology Authors: Dihui Cai Yin Fu Yongfei Song Hui Lin Yanna Ba Jiangfang Lian Source Type: research
Aortic Atherosclerosis: A Common Source of Cerebral Emboli, Often Overlooked!
We present a case of cerebral embolism arising from a mobile noncalcified complex aortic arch plaque diagnosed on a transesophageal echocardiogram and review the literature on its diagnosis, clinical implications, and management.
PMID: 25569596 [PubMed - as supplied by publisher]
Source: Atherosclerosis - January 7, 2015 Category: Cardiology Authors: Ismail I, Agarwal A, Aggarwal S, Al-Khafaji N, Gupta N, Badi H, Chopra A, Khosla S, Arora R Tags: Am J Ther Source Type: research
Can a Single Measurement of Apixaban Levels Identify Patients at Risk of Overexposure? A Prospective Cohort Study
Conclusion The trough and peak levels of apixaban in patients who have a high level on a single occasion, usually remain high when the assay is repeated in 2 months. Accordingly, the finding of a high apixaban level in patients deemed to be at high risk of bleeding, allows physicians contemplating off-label use of the 2.5-mg BID dose to limit its use to selected patients who are less likely to be exposed to an increased risk of thrombosis.PMID:35088021 | PMC:PMC8786560 | DOI:10.1055/s-0041-1740492
Source: Atherosclerosis - January 28, 2022 Category: Cardiology Authors: Tim A C de Vries Jack Hirsh Vinai C Bhagirath Jeffrey S Ginsberg Ron Pisters Martin E W Hemels Joris R de Groot John W Eikelboom Noel C Chan Source Type: research
Aldosterone and cardiovascular diseases
Cardiovasc Res. 2022 Apr 7:cvac027. doi: 10.1093/cvr/cvac027. Online ahead of print.ABSTRACTAldosterone's role in the kidney and its pathophysiologic actions in hypertension are well known. However, its role or that of its receptor [minieralocorticoid receptor (MR)] in other cardiovascular (CV) disease are less well described. To identify their potential roles in six CV conditions (heart failure, myocardial infarction, atrial fibrillation, stroke, atherosclerosis, and thrombosis), we assessed these associations in four areas: 1) mechanistic studies in rodents and humans; 2) preclinical studies of MR antagonists; 3) clinica...
Source: Atherosclerosis - April 7, 2022 Category: Cardiology Authors: Wasita W Parksook Gordon H Williams Source Type: research
Efficacy and Safety Considerations With Dose-Reduced Direct Oral Anticoagulants: A Review
CONCLUSIONS AND RELEVANCE: Dose adjustment and low-intensity treatment are 2 different forms of dose-reduced DOACs. Dose adjustment is mostly relevant for AF and should be done based on the approved criteria. Dose adjustment of DOACs should not be used for acute VTE treatment in most cases. In contrast, low-intensity DOACs may be used for primary or secondary VTE prevention for studied and approved indications. Attention should be given to routine practice patterns to align the daily clinical practice with existing evidence of safety and efficacy.PMID:35648414 | DOI:10.1001/jamacardio.2022.1292
Source: Atherosclerosis - June 1, 2022 Category: Cardiology Authors: Behnood Bikdeli Farbod Zahedi Tajrishi Parham Sadeghipour Azita H Talasaz John Fanikos Giuseppe Lippi Deborah M Siegal John W Eikelboom Manuel Monreal David Jimenez Jean M Connors Walter Ageno Geoffrey D Barnes Gregory Piazza Dominick J Angiolillo Sahil A Source Type: research
Joint Genetic Inhibition of PCSK9 and CETP and the Association With Coronary Artery Disease: A Factorial Mendelian Randomization Study
CONCLUSIONS AND RELEVANCE: Our results suggest that joint inhibition of CETP and PCSK9 has additive effects on lipid traits and disease risk, including a lower risk of CAD. Further research may explore whether a combination of CETP- and PCSK9-related therapeutics can benefit high-risk patients who are unable to reach treatment targets with existing options.PMID:35921096 | DOI:10.1001/jamacardio.2022.2333
Source: Atherosclerosis - August 3, 2022 Category: Cardiology Authors: Arjen J Cupido Laurens F Reeskamp Aroon D Hingorani Chris Finan Folkert W Asselbergs G Kees Hovingh Amand F Schmidt Source Type: research
Left Atrial Function and Arrhythmias in Relation to Small Vessel Disease on Brain MRI: The Multi-Ethnic Study of Atherosclerosis
Conclusions In individuals without a history of stroke or transient ischemic attack, alterations of LA structure and function, including enlargement, reduced strain, frequent premature atrial contractions, and intermittent AF, were associated with increased markers of small vessel disease. Detailed assessment of LA structure and function and extended ECG monitoring may enable early identification of individuals at greater risk of small vessel disease.PMID:36250665 | DOI:10.1161/JAHA.122.026460
Source: Atherosclerosis - October 17, 2022 Category: Cardiology Authors: Thomas R Austin Paul N Jensen Ilya M Nasrallah Mohamad Habes Tanweer Rashid Jeffrey B Ware Lin Yee Chen Philip Greenland Timothy M Hughes Wendy S Post Steven J Shea Karol E Watson Colleen M Sitlani James S Floyd Richard A Kronmal W T Longstreth Alain G Be Source Type: research
Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study
CONCLUSION: Our MR study suggested that longer telomeres were associated with decreased risk of several CVDs, including coronary atherosclerosis, myocardial infarction, ischemic heart disease, and stroke, as well as an increased risk of hypertension. Future studies are still warranted to validate the results and investigate the mechanisms underlying these associations.PMID:36352846 | PMC:PMC9637552 | DOI:10.3389/fcvm.2022.1012615
Source: Atherosclerosis - November 10, 2022 Category: Cardiology Authors: Yingjian Deng Qiang Li Faguang Zhou Guiyang Li Jianghai Liu Jialan Lv Linlin Li Dong Chang Source Type: research
Left Atrial Mechanical Dysfunction and the Risk for Ischemic Stroke in People Without Prevalent Atrial Fibrillation or Stroke : A Prospective Cohort Study
Ann Intern Med. 2022 Dec 20. doi: 10.7326/M22-1638. Online ahead of print.NO ABSTRACTPMID:36534978 | DOI:10.7326/M22-1638
Source: Atherosclerosis - December 19, 2022 Category: Cardiology Authors: Ankit Maheshwari Faye L Norby Riccardo M Inciardi Wendy Wang Michael J Zhang Elsayed Z Soliman Alvaro Alonso Michelle C Johansen Rebecca F Gottesman Scott D Solomon Amil M Shah Lin Yee Chen Source Type: research
Direct Oral Anticoagulants as the First Choice of Anticoagulation for Patients with Peripheral Artery Disease to Prevent Adverse Vascular Events: A Systematic Review and Meta-Analysis
J Cardiovasc Dev Dis. 2023 Feb 3;10(2):65. doi: 10.3390/jcdd10020065.ABSTRACTThe best method of anticoagulation for patients with peripheral artery disease (PAD) is still a topic of interest for physicians. We conducted a meta-analysis to compare the effects of direct oral anticoagulants (DOACs) with those of vitamin-K-antagonist (VKA) anticoagulants in patients with peripheral artery disease. Five databases (Medline (via PubMed), EMBASE, Scopus, Web of Science, and CENTRAL) were searched systematically for studies comparing the effects of the two types of anticoagulants in patients with PAD, with an emphasis on lower-limb...
Source: Atherosclerosis - February 24, 2023 Category: Cardiology Authors: Enik ő Pomozi Rita Nagy P éter Fehérvári P éter Hegyi Boldizs ár Kiss Fanni Dembrovszky Annam ária Kosztin S ándor Nardai Endre Zima Zolt án Szeberin Source Type: research
Association of Interleukin-6 and Interleukin-18 with Cardiovascular Disease in Older Adults: Atherosclerosis Risk in Communities Study
CONCLUSION: Among older adults, both IL-6 and IL-18 were associated with global CVD and death. The association between IL-6 with CVD appears to be more robust and was independent of hs-CRP, NT-proBNP, and hs-TnT.PMID:37306504 | DOI:10.1093/eurjpc/zwad197
Source: Atherosclerosis - June 12, 2023 Category: Cardiology Authors: Xiaoming Jia Leo Buckley Caroline Sun Mahmoud Al Rifai Bing Yu Vijay Nambi Salim S Virani Elizabeth Selvin Kunihiro Matsushita Ron C Hoogeveen Josef Coresh Amil M Shah Christie M Ballantyne Source Type: research
Prescriptive behavior of non-vitamin K oral anticoagulants in patients affected by atrial fibrillation in general practice
Biomed Pharmacother. 2023 Jun 21;165:115020. doi: 10.1016/j.biopha.2023.115020. Online ahead of print.ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia worldwide and in recent years the pharmacological approach has been strongly implemented; in Italy, the prescription of the non-vitamin K oral anticoagulants (NOAC) was also extended to General Practitioners (GPs) since 2020. The aim of the present study was to investigate the GPs prescribing behaviour of NOACs. An observational study was performed by using the computerized medical record of 14 GPs in Sicily: patients affected by AF were selected and st...
Source: Atherosclerosis - June 23, 2023 Category: Cardiology Authors: M Rottura S F A Drago A Molonia N Irrera S Marino R Scoglio L Orlando M Gigliotti De Fazio F Squadrito V Arcoraci E Imbalzano on the behalf of Audit & Research Messina Primary Care Group Source Type: research
