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Source: Atherosclerosis
Condition: Atrial Fibrillation

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Total 150 results found since Jan 2013.

Emerging role of miRNAs in the regulation of ferroptosis
Front Mol Biosci. 2023 Feb 15;10:1115996. doi: 10.3389/fmolb.2023.1115996. eCollection 2023.ABSTRACTFerroptosis is a kind of cell death which has distinctive features differentiating it from autophagy, necrosis and apoptosis. This iron-dependent form of cell death is described by an increase in lipid reactive oxygen species, shrinkage of mitochondria and decrease in mitochondrial cristae. Ferroptosis is involved in the initiation and progression of many diseases and is regarded as a hotspot of investigations on treatment of disorders. Recent studies have shown that microRNAs partake in the regulation of ferroptosis. The im...
Source: Atherosclerosis - March 6, 2023 Category: Cardiology Authors: Reza Mahmoudi-Lamouki Sepideh Kadkhoda Bashdar Mahmud Hussen Soudeh Ghafouri-Fard Source Type: research

Deep-Learning for Epicardial Adipose Tissue Assessment With Computed  Tomography: Implications for Cardiovascular Risk Prediction
CONCLUSIONS: Automated assessment of EAT volume is possible in CCTA, including in patients who are technically challenging; it forms a powerful marker of metabolically unhealthy visceral obesity, which could be used for cardiovascular risk stratification.PMID:36881425 | DOI:10.1016/j.jcmg.2022.11.018
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Henry W West Muhammad Siddique Michelle C Williams Lucrezia Volpe Ria Desai Maria Lyasheva Sheena Thomas Katerina Dangas Christos P Kotanidis Pete Tomlins Ciara Mahon Attila Kardos David Adlam John Graby Jonathan C L Rodrigues Cheerag Shirodaria John Dean Source Type: research

Association of abnormal p-wave parameters with brain mri morphology: the atherosclerosis risk in communities neurocognitive study (ARIC-NCS)
CONCLUSION: In this exploratory analysis of a US community-based cohort, ECG surrogates of atrial myopathy are associated with higher prevalence of brain infarcts and microhemorrhage, suggesting subclinical vascular brain injury as a possible mechanism underlying the association of atrial myopathy with dementia. This article is protected by copyright. All rights reserved.PMID:36924350 | DOI:10.1111/pace.14687
Source: Atherosclerosis - March 16, 2023 Category: Cardiology Authors: Jorge L Reyes Faye L Norby Yuekai Ji Wendy Wang Romil Parikh Michael J Zhang Niki C Oldenburg Pamela L Lutsey Clifford R Jack Michelle Johansen Rebecca F Gottesman Josef Coresh Thomas Mosley Elsayed Z Soliman Alvaro Alonso Lin Yee Chen Source Type: research

Air Pollution and Arrhythmias
Can J Cardiol. 2023 Apr 4:S0828-282X(23)00293-3. doi: 10.1016/j.cjca.2023.03.023. Online ahead of print.ABSTRACTAir pollution is commonly defined as the contamination of the air we breathe by any chemical, physical or biological agent that is potentially threatening to human and ecosystem health. The common pollutants known to be disease-causing are particulate matter, ground-level ozone, sulphur dioxide, nitrogen dioxide and carbon monoxide. Although the association between increasing concentrations of these pollutants and cardiovascular disease is now accepted, the association of air pollution and arrhythmias is less wel...
Source: Atherosclerosis - April 6, 2023 Category: Cardiology Authors: Matthew Bennett Isabelle Nault Michael Koehle Stephen Wilton Source Type: research

The Potential Cardiometabolic Effects of Long-Chain Omega-3 Polyunsaturated Fatty Acids: Recent Updates and Controversies
Adv Nutr. 2023 Apr 7:S2161-8313(23)00283-1. doi: 10.1016/j.advnut.2023.03.014. Online ahead of print.ABSTRACTVarious health-related effects of long-chain (LC) omega-3 polyunsaturated fatty acids (PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been suggested. LC omega-3 PUFAs reduce triglyceride levels and have anti-inflammatory, immunomodulatory, antiplatelet, and vascular protective effects. Controversially, they might help in restoring glucose homeostasis via the gut microbiota. However, previous studies have not shown the clear benefits of LC omega-3 PUFAs for cardiovascular diseases. REDUCE-IT...
Source: Atherosclerosis - April 9, 2023 Category: Cardiology Authors: Jae Hyun Bae Hyunjung Lim Soo Lim Source Type: research

U-shaped association between the triglyceride-glucose index and atrial fibrillation incidence in a general population without known cardiovascular disease
CONCLUSIONS: A U-shaped association between the TyG index and AF incidence is observed in Americans without known cardiovascular diseases. Female sex may be a modifier in the association between the TyG index and AF incidence.PMID:37208737 | DOI:10.1186/s12933-023-01777-9
Source: Atherosclerosis - May 19, 2023 Category: Cardiology Authors: Xiao Liu Ayiguli Abudukeremu Yuan Jiang Zhengyu Cao Maoxiong Wu Jianyong Ma Runlu Sun Wanbing He Zhiteng Chen Yangxin Chen Peng Yu Wengen Zhu Yuling Zhang Jingfeng Wang Source Type: research

Association of brain microbleeds with risk factors, cognition, and MRI markers in MESA
DISCUSSION: Results suggest differing associations for lobar versus deep locations. Sensitive microbleed quantification will facilitate future longitudinal studies of their potential role as an early indicator of vascular pathology.PMID:37289978 | DOI:10.1002/alz.13346
Source: Atherosclerosis - June 8, 2023 Category: Cardiology Authors: Paul N Jensen Tanweer Rashid Jeffrey B Ware Yuhan Cui Colleen M Sitlani Thomas R Austin W T Longstreth Alain G Bertoni Elizabeth Mamourian R Nick Bryan Ilya M Nasrallah Mohamad Habes Susan R Heckbert Source Type: research

Warfarin faring better: Vitamin K antagonists beat rivaroxaban and apixaban in the INVICTUS and PROACT Xa trials
J Thromb Haemost. 2023 Jul 8:S1538-7836(23)00523-8. doi: 10.1016/j.jtha.2023.06.036. Online ahead of print.ABSTRACTAlthough guidelines give preference to the direct oral anticoagulants (DOACs) over vitamin K antagonists (VKAs) for stroke prevention in most patients with atrial fibrillation (AF), DOACs are not recommended in those with rheumatic heart disease or mechanical heart valves. The results of the INVICTUS trial (Investigation of Rheumatic AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies), which compared rivaroxaban with a VKA in patients with rheumatic heart disease associated AF, and the PR...
Source: Atherosclerosis - July 10, 2023 Category: Cardiology Authors: John W Eikelboom Jeffrey I Weitz Source Type: research

ICAM-1 and VCAM-1: gatekeepers in various inflammatory and cardiovascular disorders
Clin Chim Acta. 2023 Jul 11:117487. doi: 10.1016/j.cca.2023.117487. Online ahead of print.ABSTRACTLeukocyte migration from the vascular compartment is critical fornormal lymphocyte recirculation in specific tissues and immune response in inflammatory locations. Leukocyte recruitment, migration to inflammatory areas, and targeting in the extravascular space are caused by cellular stimulation and local expression of adhesion molecules. Intercellular adhesion molecule 1 (ICAM-1) and Vascular cell adhesion molecule 1 (VCAM-1) belong to the immunoglobulin superfamily of cell adhesion molecules with a crucial role in mediating t...
Source: Atherosclerosis - July 13, 2023 Category: Cardiology Authors: Varinder Singh Rupinder Kaur Pratima Kumari Chirag Pasricha Ravinder Singh Source Type: research

Mitral Annular Calcification and Thromboembolic Risk
Conclusions: The presence of MAC is associated with greater TE risk scores and a higher risk of vascular disease. It appears that adding MAC as a vascular disease parameter to TE risk scores may have benefits for patients by improving their predictive value.PMID:37511943 | PMC:PMC10381637 | DOI:10.3390/life13071568
Source: Atherosclerosis - July 29, 2023 Category: Cardiology Authors: Paula Cristina Morariu Daniela Maria Tanase Diana Elena Iov Oana S îrbu Alexandru Florinel Oancea Cornel Gabriel Mircea Cristina Petronela Chiriac Genoveva Livia Baroi Ionela-Daniela Morariu Cristina Gena Dasc ălu Lauren ţiu Şorodoc Mariana Floria Source Type: research

Association of immune checkpoint inhibitors therapy with arterial thromboembolic events in cancer patients: A retrospective cohort study
CONCLUSION: ICI-treated patients may exhibit a higher risk of ATEs, especially after 1 year of treatment.PMID:37584246 | DOI:10.1002/cam4.6455
Source: Atherosclerosis - August 16, 2023 Category: Cardiology Authors: Jie Zhu Yue Chen Yuanlong Zhang Wei Wang Yujue Wang Zhuo Lu Yulin Zhang Haike Lei Dairong Li Bo Long Haixia Liu Source Type: research

Causal associations between type 1 diabetes mellitus and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: This MR study provided evidence supporting the causal effect of T1DM on peripheral atherosclerosis and coronary atherosclerosis, with hypertension partly mediating this effect.PMID:37659996 | DOI:10.1186/s12933-023-01974-6
Source: Atherosclerosis - September 2, 2023 Category: Cardiology Authors: Zirui Liu Haocheng Wang Zhengkai Yang Yu Lu Cao Zou Source Type: research