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Source: European Neurology
Condition: Atrial Fibrillation

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Total 17 results found since Jan 2013.

Effects of Direct Oral Anticoagulants ’ Nonrecommended Dose in Atrial Fibrillation: A Meta-Analysis
Background: The efficacy and safety profiles of nonrecommended direct oral anticoagulant (DOAC) doses in patients with nonvalvular atrial fibrillation (NVAF) are still undefined.Summary: We searched for randomized controlled trials and observational studies that compared nonrecommended versus recommended doses of DOACs, published up to December 2021. Primary study outcomes were ischemic stroke/transient ischemic attack/systemic embolism (IS/TIA/SE) and major bleeding (MB). All-cause mortality was a secondary outcome. We determined pooled odds ratios (ORs) between groups of patients with a random-effect model. Twenty-three ...
Source: European Neurology - September 13, 2022 Category: Neurology Source Type: research

Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke When Multiple Passes Are Required and Associated Risk Factors
Conclusion: Needing more than 2 passes during mechanical thrombectomy is associated with poorer outcomes. Higher preprocedural NIHSS scores and internal carotid artery thrombi are associated with more than 2 passes.Eur Neurol
Source: European Neurology - May 3, 2022 Category: Neurology Source Type: research

Does Chronic Kidney Disease Have an Impact on the Use of Oral Anticoagulants after Stroke? An Observational Follow-Up Study
Conclusion: Our results show that chronic kidney disease was not the main factor in the decision to withhold oral anticoagulation in patients with recent stroke/TIA and AF.Eur Neurol
Source: European Neurology - June 24, 2021 Category: Neurology Source Type: research

Prestroke Statins Improve Prognosis of Atrial Fibrillation-Associated Stroke through Increasing Suppressor of Cytokine Signaling-3 Levels
Conclusion: Our data suggested that the prestroke use of statins improved the clinical outcomes in AIS patients with AF by upregulating the level of SOCS-3 and reducing the plasma MMP-9 level.Eur Neurol
Source: European Neurology - March 8, 2021 Category: Neurology Source Type: research

Stroke in Patients with Infective Endocarditis: A 15-Year Single-Center Cohort Study
Conclusion: Stroke is a common complication of IE. Mitral valve vegetation and old age may incerease the risk of stroke in patients with IE.Eur Neurol 2018;80:171 –178
Source: European Neurology - November 28, 2018 Category: Neurology Source Type: research

Development of an Algorithm for Stroke Prediction: A National Health Insurance Database Study in Korea
Conclusion: The model developed in the present study can be applied in the clinical setting to estimate the probability of stroke in a year and thus improve the stroke prevention strategies in high-risk patients. The approach used to develop the stroke prevention algorithm can be applied for developing similar models for the pre-diagnosis of other diseases.Eur Neurol 2018;79:214 –220
Source: European Neurology - April 3, 2018 Category: Neurology Source Type: research

Portuguese Observational Study of Ischaemic Stroke in Patients Medicated with Non-Vitamin K Antagonist Oral Anticoagulants
Conclusion: Preadmission anticoagulation with NOACs in AIS has a functional impact similar to that of VKAs.Eur Neurol 2018;79:108 –112
Source: European Neurology - February 8, 2018 Category: Neurology Source Type: research

Implications of CHA2DS2-VASc Score in Stroke Patients with Atrial Fibrillation: An Analysis of 938 Korean Patients
Background and Aims: The aim of this study was to investigate the stroke mechanisms and associated conditions influencing the decision regarding stroke thromboprophylaxis in patients with atrial fibrillation (AF) plus ischemic stroke, according to the CHA2DS2-VASc score.Methods: We evaluated 938 consecutive patients with a diagnosis of AF plus transient ischemic attack/ischemic stroke. Based on the CHA2DS2-VASc scores, patients were stratified as score 0 or 1 (n = 151), score 2 (n = 146), score 3 (n = 213), score 4 (n = 185), or score ≥5 (n = 243).Results: Patients with a higher CHA2DS2-VASc score were more likely to hav...
Source: European Neurology - April 28, 2017 Category: Neurology Source Type: research

Implications of CHA < sub > 2 < /sub > DS < sub > 2 < /sub > -VASc Score in Stroke Patients with Atrial Fibrillation: An Analysis of 938 Korean Patients
Background and Aims: The aim of this study was to investigate the stroke mechanisms and associated conditions influencing the decision regarding stroke thromboprophylaxis in patients with atrial fibrillation (AF) plus ischemic stroke, according to the CHA2DS2-VASc score.Methods: We evaluated 938 consecutive patients with a diagnosis of AF plus transient ischemic attack/ischemic stroke. Based on the CHA2DS2-VASc scores, patients were stratified as score 0 or 1 (n = 151), score 2 (n = 146), score 3 (n = 213), score 4 (n = 185), or score ≥5 (n = 243).Results: Patients with a higher CHA2DS2-VASc score were more likely to hav...
Source: European Neurology - April 28, 2017 Category: Neurology Source Type: research

Frequency and Determinants of Adherence to Oral Anticoagulants in Stroke Patients with Atrial Fibrillation in Clinical Practice
Background: Vitamin K antagonists (VKAs) and non-VKA oral anticoagulants (NOACs) are beneficial in patients with stroke and atrial fibrillation (AF). However, little is known about frequency and determinants of adherence to NOACs/VKAs in clinical practice.Methods: This is a single-center explorative study from the Novel Oral Anticoagulants in Stroke Patients (NOACISP)-LONGTERM registry. We included consecutive AF-stroke patients treated with NOACs/VKAs and followed up for 3-24 months. Adherence was assessed at follow-up using structured interviews and quantified as the proportion of prescribed doses taken (PDT). Outcome me...
Source: European Neurology - October 5, 2016 Category: Neurology Source Type: research

Predictive Factors for Excellent or Extremely Poor Functional Outcome in Initial Atrial Fibrillation-Related Cardioembolic Stroke
Conclusions: Predictive factors exist to delineate excellent and extremely poor functional outcomes after a first-time stroke associated with AF.Eur Neurol 2016;76:105-111
Source: European Neurology - August 10, 2016 Category: Neurology Source Type: research

Susceptibility Vessel Sign in Isolated Brainstem Infarction with Large Artery Occlusion
Conclusions: SVS reflects pathology of deoxidized red cells composition in patients with isolated brainstem infarction. This finding may be useful to explore the different stroke mechanisms and therapy strategies.Eur Neurol 2016;75:251-256
Source: European Neurology - May 12, 2016 Category: Neurology Source Type: research

New-Onset Paroxysmal Atrial Fibrillation Diagnosis in Ischemic Stroke Patients
Conclusions: This risk prediction model can be helpful to estimate the risk of an underlying pAF within 3 months after suffering an IS/TIA, contributing to increased AF detection efforts, thereby starting the correct secondary prevention treatment.Eur Neurol 2015;74:211-217
Source: European Neurology - November 26, 2015 Category: Neurology Source Type: research

Reasons Underlying Non-Adherence to and Discontinuation of Anticoagulation in Secondary Stroke Prevention among Patients with Atrial Fibrillation
Conclusion: Nonadherence to OAC in stroke patients results from fear of potential complications or inconvenience and physicians' concerns regarding functional status. OAC should be initiated wherever possible during the in-hospital stay.Eur Neurol 2015;73:184-191
Source: European Neurology - January 24, 2015 Category: Neurology Source Type: research

Timing of Neurological Improvement after Acute Ischemic Stroke and Functional Outcome
Conclusions: These results suggest that TNI is independently associated with functional outcome at 90 days. TNI2 may be more useful than TNI4 for early prediction of stroke outcome.Eur Neurol 2015;73:164-170
Source: European Neurology - January 13, 2015 Category: Neurology Source Type: research