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Clinical Experience of Life-Threatening Dabigatran-Related Bleeding at a Large, Tertiary Care, Academic Medical Center: a Case Series.
CONCLUSION: Reversal strategies for dabigatran-related bleeding events at our institution are highly variable. Intracranial hemorrhage in patients on dabigatran was associated with 43 % mortality. Patients with severe dabigatran-related bleeding may benefit from a standardized approach to treatment. PMID: 24385325 [PubMed - as supplied by publisher]
Source: Journal of Medical Toxicology - January 3, 2014 Category: Toxicology Authors: Ross B, Miller MA, Ditch K, Tran M Tags: J Med Toxicol Source Type: research

Management of Bleeding Complications in Patients Taking Direct Oral Anticoagulants at a Large Tertiary Academic Medical Center
Abstract Direct oral anticoagulants (DOACs) offer a fixed-dose alternative to warfarin for stroke prevention in patients with atrial fibrillation. However, there is minimal evidence to guide the management of bleeding in patients taking a DOAC. We retrospectively evaluated the acute management of major bleeding in this patient population at a large, tertiary academic medical center. We evaluated various strategies of management including dialysis, transfusions, pharmacologic agents, surgical intervention, and reinitiation of anticoagulation. We also assessed length of intensive care unit and hospital stay, mor...
Source: Current Emergency and Hospital Medicine Reports - June 13, 2015 Category: Emergency Medicine Source Type: research

Prosthesis Choice in Dialysis Patients Undergoing Mitral Valve Replacement
CONCLUSIONS: MVR in dialysis patients carries significant morbidity and increased mid-term mortality. Decreased life-expectancy should be considered in the tailoring of prosthesis choice to dialysis-dependent patients.PMID:37245789 | DOI:10.1016/j.athoracsur.2023.05.015
Source: The Annals of Thoracic Surgery - May 28, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Amit Iyengar Cindy Song Noah Weingarten David Rekhtman David A Herbst Max Shin Mark R Helmers Pavan Atluri Source Type: research