• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Recurrent Alternating Homonymous Hemianopia Due to Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-Like Episodes (MELAS) (P4.260)
CONCLUSIONS: We describe a unique phenomenon of recurrent alternating homonymous hemianopia in MELAS, which should prompt consideration of this diagnosis.Disclosure: Dr. Krysko has nothing to disclose. Dr. Arun has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Krysko, K., Arun, S. Tags: Neuro-ophthalmology/Neuro-otology Source Type: research

Dural Arteriovenous Fistula, Medullary Edema, and Ondines Curse: A Case Report (P3.195)
Conclusions: New onset respiratory failure due to dysfunction in the CNS, called acquired central alveolar hypoventilation, has been seen in several common conditions that may affect the medulla, including demyelinating lesions and stroke. We report the first case of acquired central alveolar hypoventilation due to dAVF, where apnea during sleep (was the patient’s only residual neurologic deficit after treatment, the so-called Ondine’s curse. Clinicians evaluating hypercapnic respiratory failure should consider brainstem pathology that may impair central respiratory function and consider a dedicated angiography...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Culler, G., Afshari, M., Maas, M. Tags: Neurocritical Care: Clinical Science Source Type: research

Thiamine Deficiency While on Total Parenteral Nutrition Mimicking Acute Stroke: A Case Report (P3.217)
CONCLUSIONS: Thiamine deficiency mimicking stroke while on total parenteral nutrition has been rarely documented. Recognition of this syndrome is critical as prompt treatment may reverse symptoms.Disclosure: Dr. Parker has nothing to disclose. Dr. Marafie has nothing to disclose. Dr. Wolf has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Parker, A., Marafie, D., Wolf, V. Tags: Neurocritical Care: Clinical Science and Therapeutics Source Type: research

A Case of Resolution of Thalamic Pain Syndrome Following Endovascular Stenting (P4.352)
Conclusions: CPSP may be in part due to chronic hypoperfusion. Endovascular stenting may have led to the resolution of the patient’s CPSP.Disclosure: Dr. Le has nothing to disclose. Dr. Rasmussen has nothing to disclose. Dr. Noonan has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Le, S., Rasmussen, J., Noonan, P. Tags: Cerebrovascular Case Reports Source Type: research

Recurrent Strokes in Giant Cell Arteritis: Treatment Dilemma (P4.374)
Conclusions: Steroid resistant, aggressive GCA cases can lead to severe extracranial vasculopathy, dissection, recurrent strokes, and death. Thus we suggest that aggressive immunosuppression be considered early, particularly if complicated with arterial dissection and stroke. These patients may benefit from other potent immunosuppressant drugs such as disease modifying anti-rheumatic drugs, acyclovir, or monoclonal antibodies.Disclosure: Dr. Yadala has nothing to disclose. Dr. Kaur has nothing to disclose. Dr. Sahni has nothing to disclose. Dr. Lleva has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yadala, V., Kaur, P., Sahni, R., Lleva, P. E. Tags: Cerebrovascular Case Reports Source Type: research

Is It Possible to Treat "Stroke-Like Symptoms" with Hemodialysis? (P4.390)
CONCLUSIONS • Diabetic patients with ESRD on HD can present with stroke-like symptoms associated with bilateral basal ganglia hypoattenuation . This presentation can be confused initially with a stroke. • Brain imaging can assist with making the diagnosis. The clinical presentation in our cases included slurred speech, ataxia, and bilateral lower extremity weakness. • Hemodialysis leaded to clinical improvement.Disclosure: Dr. Rodriguez Alvarez has nothing to disclose. Dr. Pillai has nothing to disclose. Dr. Gomez has nothing to disclose. Dr. Avagyan has nothing to disclose. Dr. Gold has nothing to disclose....
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rodriguez Alvarez, M., Pillai, A., Gomez, E., Avagyan, A., Gold, M., Sternman, D., Thompson, L. Tags: General Neurology: Vascular Disease and Imaging Source Type: research

A Rare Presentation of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) as Acute Ischemic Stroke (P6.112)
CONCLUSIONS: This case illustrates not only a classic clinical and radiographic case of CLIPPERS, but also that this recently recognized disorder can be easily misdiagnosed as a neuromuscular disease in the early stages, and stroke in the more severe stages. Rarely, the inflammatory infiltrate can result in stroke in these patients, and is likely the cause of the acute exacerbation of our patient’s symptoms. This case also demonstrates the need for contrast imaging whenever possible, as the non-contrast imaging failed to identify the characteristic diffuse enhancing punctate lesions.Disclosure: Dr. Gadhia has nothing...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gadhia, R., Smith, S., Lai, E., Lee, A. Tags: MS and CNS Inflammatory Disease: CNS Inflammatory Diseases and Differential Diagnosis Source Type: research

The Role of Staufen1 in Aberrant RNA Metabolism in SCA2 (P6.396)
Conclusions: Our results unravel a novel function for Staufen1 in aberrant RNA processing events and indicate its role in SCA2 pathogenesis. Our results further support a role for aberrant RNA metabolism in neurodegeneration thereby revealing its potential as a therapeutic target. Study Supported by: This work was supported by Grants RO1NS33123 and RC4NS073009 from the National Institutes of Neurological Disorders and Stroke to SMP.Disclosure: Dr. Paul has nothing to disclose. Dr. Dansithong has nothing to disclose. Dr. Figueroa has nothing to disclose. Dr. Scoles has nothing to disclose. Dr. Pulst has received personal co...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Paul, S., Dansithong, W., Figueroa, K., Scoles, D., Pulst, S. Tags: Movement Disorders: Spinocerebellar Ataxias Source Type: research

Vascular gait disorders: What's the matter with the white and gray matter?
Small vessel disease is the commonest known brain disorder, and, among its hallmarks, difficulty walking is a major cause of increased dependency and reduced quality of life, as well as death. Although gait problems relate to the presence and extent of various neuroimaging markers of small vessel disease (e.g., white matter hyperintensities, lacunes, and cerebral microbleeds), the exact mechanisms involved, and any additional role of neurodegenerative pathology, are not well-understood. A key question is how small vessel disease affects white matter integrity and ultimately motor and cognitive function to result in clinical symptoms.
Source: Neurology - March 27, 2016 Category: Neurology Authors: Werring, D. J., Camicioli, R. M. Tags: Other cerebrovascular disease/ Stroke, Gait disorders/ataxia, All Cerebrovascular disease/Stroke, Vascular dementia, Cognitive aging EDITORIALS Source Type: research

Teaching Video NeuroImages: Alternating skew deviation with abducting hypertropia following superior colliculus infarction
A 63-year-old patient was admitted with acute ataxia and binocular oblique diplopia. Neuro-ophthalmologic examination revealed abducting hypertropia on lateral gaze, better seen during upgaze, mimicking bilateral inferior oblique palsy (video, figure). There was no ocular cyclotorsion. Brain MRI revealed focal ischemic lesions in the right cerebellar hemisphere and left superior colliculus (figure). The diagnosis of alternating abducting hypertropic skew deviation was made. This rare type of skew deviation is related to central otolithic dysfunction. Similar cases have been described with cerebellar, pretectal, or cervico-...
Source: Neurology - February 29, 2016 Category: Neurology Authors: Biotti, D., Barbieux, M., Brassat, D. Tags: MRI, Clinical neurology examination, Ocular motility, Diplopia (double vision), All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Proximal Occlusion Scale for Rapid Triage of Potential Endovascular Therapy Candidates (S47.002)
Conclusions: We report a proximal occlusion score to rapidly identify and triage patients most likely to benefit from urgent evaluation for endovascular therapy. Using multivariate analysis selected features of the presenting neurological exam were predictive of proximal arterial occlusion significantly better that that achieved by an NIHSS cutoff. The proximal occlusion scale could be performed faster than the NIHSS. Utilization of this tool in community hospitals without direct neurologist support may aid in the triage of stroke patients in need of endovascular therapy. Further evaluation in larger cohorts is required.Di...
Source: Neurology - February 7, 2016 Category: Neurology Authors: Holder, D., Jickling, G. Tags: IV-tPA and Endovascular Therapy Source Type: research

Deep brain stimulation of the dentate nucleus improves cerebellar ataxia after cerebellar stroke
The cerebrocerebellum receives input from the cerebral cortex and projects to the motor and premotor cortices and the ventrolateral nucleus of the thalamus via the dentate nucleus (DN). Dentothalamocortical projections modulate the activity of the contralateral primary motor (M1) cortex and are involved in movement planning. Acute ischemic injury of the cerebellar nuclei leads to ataxia and a loss of physiologic excitatory inputs from the DN to the contralateral M1 cortex.1 However, chronic cerebellar ischemic lesions have been associated with a reemerging decrease in intracortical inhibition (ICI) in the contralesional M1...
Source: Neurology - December 7, 2015 Category: Neurology Authors: Teixeira, M. J., Cury, R. G., Galhardoni, R., Barboza, V. R., Brunoni, A. R., Alho, E., Lepski, G., Ciampi de Andrade, D. Tags: CLINICAL/SCIENTIFIC NOTES Source Type: research

Creutzfeldt-Jakob Disease Presenting as Stroke: Case Report and Literature Review (P1.022)
CONCLUSIONS CJD develops primarily within a population in whom stroke risk factors are common and represents a rare but important stroke mimic. Negative sensitive imaging in elderly patients with apparent acute vascular syndromes should prompt diagnostic review including consideration of prion diseases.Disclosure: Dr. Van Heuven has nothing to disclose. Dr. Boggild has nothing to disclose. Dr. White has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Van Heuven, A., Boggild, M., White, R. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Phenotypes and Genotypes of Mitochondrial Disease- Findings from A National Mitochondrial Disease Cohort (P2.061)
Conclusion: This national cohort offers a unique opportunity to deep phenotype a large group of mitochondrial disease patients, bridge the gap in our understanding of disease progression, develop clinical guideline on patient care and facilitate patient recruitment for any future trials.Disclosure: Dr. Ng has nothing to disclose. Dr. Gorman has nothing to disclose. Dr. Nesbitt has nothing to disclose. Dr. Pitceathly has nothing to disclose. Dr. Grady has nothing to disclose. Dr. Schaefer has nothing to disclose. Dr. Bright has nothing to disclose. Dr. Feeney has nothing to disclose. Dr. Rahman has nothing to disclose. Dr. ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ng, Y. S., Gorman, G., Nesbitt, V., Pitceathly, R., Grady, J., Schaefer, A., Bright, A., Feeney, C., Rahman, S., Poulton, J., Taylor, R., Hanna, M., Turnbull, D., McFarland, R. Tags: ALS and Motor Neuron Disease Source Type: research

Early Diagnosis of Posterior Fossa Stroke with Brainstem Evoked Potentials (I1-3B)
Conclusion: BAP is more sensitive for diagnostic purposes towards posterior fossa small strokes and should be considered in patients when the initial MRI brain is negative. This will allow for correct diagnosis and treatment regimen without causing a delay for the patient.Disclosure: Dr. Duggal has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Duggal has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Duggal, N., Ahmed, I., Duggal, N. Tags: New Windows into the Brain: Technological Advances in Frontline Neurologic Diagnosis via the Visual and Oculomotor Systems Data Blitz Presentations Source Type: research

Pages: 1  2  3  4