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Nuclear factor-¿B activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Background: Nuclear factor-κB (NF-κB) plays an important role in the inflammatory response after intracerebral hemorrhage (ICH). We therefore proposed that NF-κB activation in perihematomal brain tissue might correlate with clinical outcome in patients with ICH. To confirm this, we studied clinical data of 45 patients with ICH and NF-κB activation in perihematomal brain tissue and analyzed predictors of clinical outcome as well as the predictive value of NF-κB activation. Methods: Forty-five patients with spontaneous basal ganglia hemorrhage were prospectively investigated. The clinical data were collected, which incl...
Source: Journal of Neuroinflammation - March 15, 2015 Category: Neurology Authors: Ze-Li ZhangYu-Guang LiuQi-Bing HuangHong-Wei WangYan SongZhen-Kuan XuFeng Li Source Type: research

Nuclear factor-κB activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Background: Nuclear factor-κB (NF-κB) plays an important role in the inflammatory response after intracerebral hemorrhage (ICH). We therefore proposed that NF-κB activation in perihematomal brain tissue might correlate with clinical outcome in patients with ICH. To confirm this, we studied clinical data of 45 patients with ICH and NF-κB activation in perihematomal brain tissue and analyzed predictors of clinical outcome as well as the predictive value of NF-κB activation. Methods: Forty-five patients with spontaneous basal ganglia hemorrhage were prospectively investigated. The clinical data were collected, which incl...
Source: Journal of Neuroinflammation - March 15, 2015 Category: Neurology Authors: Ze-Li ZhangYu-Guang LiuQi-Bing HuangHong-Wei WangYan SongZhen-Kuan XuFeng Li Source Type: research