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Left Atrial Appendage Occlusion as Adjunctive Therapy to Anticoagulation for Stroke Recurrence.
CONCLUSIONS: LAAO as an adjunctive therapy to OAC seems to be feasible and safe in patients with previous cardioembolic events despite optimal OAC. In our series, this strategy was associated with a low rate of cerebrovascular events after LAAO. PMID: 31088992 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - May 16, 2019 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Low Incidence of Ischemic Stroke Associated With Thrombus Aspiration in STEMI Patients Undergoing Primary PCI
CONCLUSIONS: Very low stroke rates immediately post STEMI were seen in patients undergoing TA and PPCI in this real-world study. TA can be performed safely in STEMI patients undergoing PPCI with a short-term stroke risk equivalent to risk without TA. Further studies may be needed to explain the increased incidence of late stroke noted after TA and elucidate causative mechanisms.PMID:34433694
Source: The Journal of Invasive Cardiology - August 26, 2021 Category: Cardiology Authors: Siddharth J Trivedi Mark J Cooper Andrew T L Ong A Robert Denniss Source Type: research

Preserved Left Atrial Function Following Left Atrial Appendage Closure for Stroke Prevention.
CONCLUSION: LA function is crucial for cardiovascular function and recurrence of AF. Our study provides evidence that LA appendage closure preserves LA function, determined by strain imaging in patients with paroxysmal AF and sinus rhythm during echocardiography. PMID: 33385985 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - January 3, 2021 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Immediate Improvement in Left Atrial Function After Transcatheter Aortic Valve Replacement on Doppler Echocardiography.
CONCLUSIONS: There is immediate improvement in LA function and an increase in LAA velocities after TAVR. This improvement may benefit hemodynamics immediately after TAVR, but may also increase the short-term stroke risk (as recently shown in two independent studies) in patients with LAA thrombus or low emptying velocities. Therefore, evaluation of LA function and LAA thrombus may be warranted to identify patients at high risk for periprocedural stroke and guide the need for anticoagulation therapy. PMID: 30418165 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - November 14, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Rheolytic Thrombectomy for Acute Myocardial Infarction Complicated by Cardiogenic Shock.
CONCLUSION: RT reduces 2-year MACE rate in patients with large thrombus burden and AMI complicated by CS. PMID: 27187985 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - May 18, 2016 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Impact of Impaired Renal Function in Patients With Severely Calcified Coronary Lesions Treated With Orbital Atherectomy.
CONCLUSION: Despite higher-risk baseline characteristics, patients with CKD had no significant differences in MACCE. Orbital atherectomy represents a reasonable treatment strategy for the treatment of severe CAC in patients with CKD. A prospective randomized trial with long-term follow-up is needed to identify the optimal treatment for these patients. PMID: 28089999 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - January 18, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

A New Strategy for Transcatheter Left Atrial Appendage Closure With Cerebral Embolic Protection in Patient With Left Auricular Thrombosis and Total Contraindication to Long-Term Anticoagulation.
We describe a clinical case with permanent AF, absolute contraindication to long-term anticoagulation therapy, and persistent thrombus formation in the LAA that was treated with transcatheter LAA closure and supraaortic trunk protection system in order to avoid risk of periprocedural stroke. PMID: 28255107 [PubMed - in process]
Source: The Journal of Invasive Cardiology - March 5, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Outcomes of Patients With a History of Coronary Artery Bypass Grafting Who Underwent Orbital Atherectomy for Severe Coronary Artery Calcification.
CONCLUSION: Despite a higher-risk baseline profile, patients with a history of CABG had similar angiographic and clinical outcomes compared with patients who had no previous history of CABG. Further studies are needed to clarify the role of orbital atherectomy in these patients. PMID: 28974662 [PubMed - in process]
Source: The Journal of Invasive Cardiology - October 6, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Comparison of Heparin and Bivalirudin in Patients Undergoing Orbital Atherectomy.
CONCLUSION: Both heparin and bivalirudin were safe and effective antithrombotic agents for patients who underwent orbital atherectomy. A randomized trial is needed to determine the antithrombotic agent of choice for orbital atherectomy. PMID: 29086730 [PubMed - in process]
Source: The Journal of Invasive Cardiology - November 2, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Impact of the Use of Intravascular Imaging on Patients Who Underwent Orbital Atherectomy.
CONCLUSION: Orbital atherectomy guided by intravascular imaging is feasible and safe. A large prospective randomized trial is needed to determine the clinical benefit of IVUS/OCT during PCI with orbital atherectomy. PMID: 29378972 [PubMed - in process]
Source: The Journal of Invasive Cardiology - January 31, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Multicenter Registry of Real-World Patients With Severely Calcified Coronary Lesions Undergoing Orbital Atherectomy: 1-Year Outcomes.
CONCLUSION: Orbital atherectomy is a valuable option for the treatment of severely calcified coronary arteries, including patients with very complex coronary anatomy and severe underlying comorbid conditions. Orbital atherectomy provided acceptable outcomes at 1 year and compared favorably to historical controls. A randomized trial with longer follow-up is needed to determine the optimal treatment strategy for patients with severely calcified coronary lesions. PMID: 29610442 [PubMed - in process]
Source: The Journal of Invasive Cardiology - April 5, 2018 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

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