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Clopidogrel underactivity is a common in patients with acute symptomatic severe carotid stenosis
Clopidogrel is commonly used for secondary stroke prevention in patients with large vessel stenosis. Reduced Clopidogrel high on treatment platelet reactivity (CR) can lead to Clopidogrel underactivity (CU) causing acute thrombosis. However, the prevalence of CU among patients with acute symptomatic carotid disease remains unknown. Therefore, we aimed to find the prevalence and identify the predictors for CU among patients with acutely symptomatic carotid stenosis.
Source: Journal of the Neurological Sciences - April 14, 2021 Category: Neurology Authors: A. Honig, T. Sacagiu, A. Filioglo, N. Simaan, J. Kalish, J.M. Gomori, A. Horev, R.R. Leker, J.E. Cohen Tags: Clinical short communication Source Type: research

Clot evaluation and distal embolization risk during mechanical thrombectomy in anterior circulation stroke
Clot features along with patients' clinical features may influence thrombus compactness predisposing at distal embolization during thrombectomy. The aim of this study was to evaluate thrombus features assessed by radiological and histopathological analysis along with patient-related features to predict distal embolization during thrombectomy.
Source: Journal of the Neurological Sciences - December 13, 2021 Category: Neurology Authors: Fabio Pilato, Iacopo Valente, Rosalinda Calandrelli, Andrea Alexandre, Vincenzo Arena, Marco Dell'Aquila, Aldobrando Broccolini, Giacomo Della Marca, Roberta Morosetti, Giovanni Frisullo, Valerio Brunetti, Marisa Distefano, Alessandro Pedicelli, Cesare Co Source Type: research

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