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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Thrombosis
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Total 415 results found since Jan 2013.
Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-analysis of Incidence, Outcomes and Predictors
COVID-19 is a multi-system infection which predominantly affects the respiratory system, but also causes systemic inflammation, endothelialitis and thrombosis. The consequences of this include renal dysfunction, hepatitis and stroke. In this systematic review, we aimed to evaluate the epidemiology, clinical course, and outcomes of patients who suffer from stroke as a complication of COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - December 15, 2020 Category: Neurology Authors: Isabel Siow, Keng Siang Lee, John J.Y. Zhang, Seyed Ehsan Saffari, Adeline Ng, Barnaby Young Source Type: research
Utilization and Outcomes of Acute Revascularization Treatment in Ischemic Stroke Patients with SARS-CoV-2 Infection
Our understanding of outcomes in acute ischemic stroke patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection following acute revascularization treatments (as intravenous thrombolysis and/or thrombectomy) is based on small case series.1-3. An international panel4 cautioned regarding the potential for high rate of death or disability and post thrombolytic intracerebral hemorrhage (ICH)s in acute ischemic stroke patients with SARS-CoV-2 infection due to elevated concentrations of inflammation and hypercoagulability markers such as leukocytosis, and C reactive protein and D dimers and multisystem dysfunction.
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2021 Category: Neurology Authors: Adnan I. Qureshi, William I. Baskett, Wei Huang, Muhammad F. Ishfaq, S. Hasan Naqvi, Brandi R. French, Farhan Siddiq, Camilo R. Gomez, Chi-Ren Shyu Tags: SARS-CoV-2 and acute revascularization Source Type: research
Workforce Attachment after Ischemic Stroke – The Importance of Time to Thrombolytic Therapy
The ability to remain in employment addresses an important consequence of stroke beyond the usual clinical parameters. However, data on the association between time to intravenous thrombolysis and workforce attachment in patients with acute ischemic stroke are sparse.
Source: Journal of Stroke and Cerebrovascular Diseases - August 24, 2021 Category: Neurology Authors: Jawad H. Butt, Kristian Kragholm, Christina Kruuse, Hanne Christensen, Helle K. Iversen, S øren Paaske Johnsen, Rasmus Rørth, Naja Emborg Vinding, Adelina Yafasova, Christine Benn Christiansen, Gunnar H. Gislason, Christian Torp-Pedersen, Lars Køber, E Source Type: research
Utilization and Outcomes of Acute Revascularization Treatments in Ischemic Stroke Patients with SARS-CoV-2 Infection
Our understanding of outcomes in acute ischemic stroke patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection following acute revascularization treatments (as intravenous thrombolysis and/or thrombectomy) is based on small case series.1 –3 An international panel4 cautioned regarding the potential for high rate of death or disability and post thrombolytic intracerebral hemorrhage (ICH)s in acute ischemic stroke patients with SARS-CoV-2 infection due to elevated concentrations of inflammation and hypercoagulability markers such as leukocytosis, and C reactive protein and D dimers and multisystem dysfunction.
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2021 Category: Neurology Authors: Adnan I. Qureshi, William I. Baskett, Wei Huang, Muhammad F. Ishfaq, S. Hasan Naqvi, Brandi R. French, Farhan Siddiq, Camilo R. Gomez, Chi-Ren Shyu Source Type: research
Cryptogenic, Embolic Stroke —Looking Backstage
Stroke is a common and devastating event and the majority of cases are caused by thromboembolism from the left atrium, left ventricle or left sided valves. This case report describes a case of embolic stroke with the origin of the thrombus from the left inferior pulmonary vein. The importance of this case is twofold. Firstly, it is the fourth case report of pulmonary venous thrombosis, a very rare condition, due to COVID-19 infection and secondly, it focuses attention on the fact that the left atrium is not the most proximal address of arterial thromboembolism —the pulmonary veins are.
Source: Journal of Stroke and Cerebrovascular Diseases - March 2, 2022 Category: Neurology Authors: Prof James Ker Tags: Case Report Source Type: research
Cerebral Infarction due to Severe ADAMTS-13 Deficiency with Normal Hematological Parameters: A Cause of Cryptogenic Stroke
Stroke is a leading cause of death and disability worldwide, and there are 1.3 million strokes annually in adults less than 50 years old.1 Many of these strokes are cryptogenic, with no clear etiology identified. In this setting clinicians frequently test for rare causes of thrombosis including hyperhomocystinemia, antiphospholipid syndrome, Factor V Leiden, prothrombin gene mutations, and protein C, S or antithrombin deficiency. Thrombotic thrombocytopenic purpura (TTP) causes arterial thrombosis, but is rarely considered in the evaluation of cryptogenic stroke with normal or near-normal hematologic profiles.
Source: Journal of Stroke and Cerebrovascular Diseases - March 16, 2022 Category: Neurology Authors: Andrew Matthews, Jennifer Yui, Elaine Y. Chiang, Allyson M. Pishko, Adam Cuker, Brett L. Cucchiara, Donna George, Farzana Sayani, Michael T. Mullen Tags: Short Communication Source Type: research
Similarities and Differences in Systemic Risk Factors for Retinal Artery Occlusion and Stroke: A Nationwide Case-Control Study
This study compares risk factor profiles for thromboembolism among patients with RAO and stroke, respectively.
Source: Journal of Stroke and Cerebrovascular Diseases - June 28, 2022 Category: Neurology Authors: Marie Ørskov, Henrik Vorum, Torben Bjerregaard Larsen, Gregory Y.H. Lip, Toke Bek, Flemming Skjøth Source Type: research
Trends in post-discharge prophylactic anticoagulant use among stroke patients in the United States between 2006 and 2019
Stroke is an independent risk factor for venous thromboembolism (VTE). Although the risk of VTE persists after hospital discharge, information on the utilization of anticoagulants among stroke patients after discharge remains limited.
Source: Journal of Stroke and Cerebrovascular Diseases - August 12, 2022 Category: Neurology Authors: Ghadeer K. Dawwas, Adam Cuker, Aaron Rothstein, Sean Hennessy Source Type: research
Recombinant tissue plasminogen activator (rTPA) management for first onset acute Ischemic Stroke with covid -19 and non-covid -19 patients
In this study we compare the efficacy and safety of Tissue plasminogen activator (rTPA) in acute ischemic stroke (AIS) patients with or without Covid-19 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2023 Category: Neurology Authors: Eman M Khedr, Ahmed Abdelwarith, Gehad M Moussa, Mostafa Saber Source Type: research
Risk of recurrent ischemic stroke in patients with patent foramen ovale: The role of D-dimer
Paradoxical embolism under elevated thromboembolic conditions is known to be the primary mechanism of patent foramen ovale (PFO)-related stroke. We hypothesized that higher levels of D-dimer, a marker of thromboembolism, could increase the risk of stroke recurrence in patients with PFO.
Source: Journal of Stroke and Cerebrovascular Diseases - August 1, 2023 Category: Neurology Authors: Seongho Park, Boseong Kwon, Jin Kyung Oh, Jae-Kwan Song, Ji Sung Lee, Sun U. Kwon Source Type: research
Efficacy and Safety of a Modified Intravenous Recombinant Tissue Plasminogen Activator Regimen in Chinese Patients with Acute Ischemic Stroke
This study was designed to verify the safety and efficacy of IV rtPA treatment for AIS with a lower dosage (0.90 mg/kg, with a maximum dose of 50 mg). Patients were divided into 3 dosage groups according to body weight (BW): group 1, 67 kg for
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2012 Category: Neurology Authors: Shu-Ming Pan, Jia-Fu Liu, Ming Liu, Sa Shen, Hao-Jun Li, Li-Hua Dai, Xiang-Jun Chen Tags: Original Articles Source Type: research
Cerebral Embolic Stroke after Disappearing Takotsubo Cardiomyopathy
Takotsubo cardiomyopathy can induce cerebral embolic stroke because of intracardiac thrombosis, but the timing of cardiogenic embolism relating to takotsubo cardiomyopathy has not been well described. We evaluated a 71-year-old woman with takotsubo cardiomyopathy, who developed cardiogenic cerebral embolism after recovery of cardiac wall motion. Nevertheless, we treated her with anticoagulation therapy. The present clinical observation suggests that attention should be paid to the timing when takotsubo cardiomyopathy resolves against risk of cardiogenic cerebral embolism.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Kosuke Matsuzono, Yoshio Ikeda, Shoko Deguchi, Toru Yamashita, Tomoko Kurata, Kentaro Deguchi, Koji Abe Tags: Case Reports Source Type: research
Fragmental or Massive Embolization in Cardiogenic Stroke Caused by Nonvalvular Atrial Fibrillation
Background: After cardioembolic stroke (CES), left atrial thrombus (LAT) is detected by transesophageal echocardiography (TEE) in some cases but not in others. We propose that there are 2 types of embolization in CES: fragmental and massive embolization.Methods: Consecutive patients with nonvalvular atrial fibrillation (AF) of acute CES or transient ischemic attack (TIA) were prospectively enrolled in the study between May 2009 and July 2011. TEE was performed within 7 days of admission. The patients were classified into 2 groups: those with occlusion of the main trunk (internal carotid artery, M1, and basilar artery; grou...
Source: Journal of Stroke and Cerebrovascular Diseases - October 18, 2012 Category: Neurology Authors: Hirokazu Sadahiro, Akinori Inamura, Hideyuki Ishihara, Ichiro Kunitsugu, Hisaharu Goto, Fumiaki Oka, Satoshi Shirao, Hiroshi Yoneda, Yasuaki Wada, Michiyasu Suzuki Tags: Original Articles Source Type: research
Recurrent Ischemic Stroke in a Patient with the Trousseau Syndrome Treated with Dabigatran
A 70-year-old man with multiple ischemic strokes was diagnosed with cardiac embolism and treated with dabigatran. Three months later, he suddenly developed vertigo and vomiting. Magnetic resonance imaging, showed recurrent lesions and blood tests revealed hypercoagulability, hypoproteinemia, and elevated cytokeratin 19 fragments that serve as a tumor marker of lung cancer. Chest computed tomography showed there were small nodules in bilateral lungs and swollen mediastinal lymph nodes. A conclusive diagnosis was impossible because the patient declined invasive procedures. We suspected primary lung cancer and diagnosed conco...
Source: Journal of Stroke and Cerebrovascular Diseases - February 21, 2014 Category: Neurology Authors: Kosuke Yoshida, Takashi Kimura, Yoko Aburakawa, Yasuhiro Suzuki, Kenji Kuroda, Osamu Yahara Tags: Case Reports Source Type: research
Demographic and Clinical Predictors of Leptomeningeal Collaterals in Stroke Patients
Background: Leptomeningeal collaterals improve outcome after stroke, including reduction of hemorrhagic complications after thrombolytic or endovascular therapy, smaller infarct size, and reduction in symptoms at follow-up evaluation. The purpose of this study was to determine the demographic and clinical variables that are associated with a greater degree of cerebral collaterals.Methods: Clinical data of patients presenting with M1 occlusions of the middle cerebral artery (MCA) and associated computed tomography angiography studies after admission from 3 separate institutions were retrospectively compiled (n = 82). Occl...
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Nitin Malik, Qinghua Hou, Achala Vagal, James Patrie, Wenjun Xin, Patrik Michel, Ashraf Eskandari, Tudor Jovin, Max Wintermark Tags: Original Articles Source Type: research
