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Source: Current Neurovascular Research
Condition: Thrombosis

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Total 42 results found since Jan 2013.

Diindolylmethane Ameliorates Ischemic Stroke-Induced Brain Injury by Peripheral and Central Mechanisms
CONCLUSION: This inhibition of platelet aggregation, platelet mediated oxidative stress, and inflammation, improved blood flow, and reduced neurological deficits, brain infarction, BBB leakage, brain water content, and histopathological abnormalities indicate the preservation of brain structural integrity. Therefore, these findings conclude that DIM exhibits neuroprotection by inhibiting platelet aggregation. Thus, the present study provided preclinical evidence of DIM neuroprotection against ischemic stroke.PMID:36397630 | DOI:10.2174/1567202620666221116161128
Source: Current Neurovascular Research - November 18, 2022 Category: Neurology Authors: Ramakrishna Kakarla Sushil Kumar Singh Sairam Krishnamurthy Source Type: research

Inverted U-shaped relationship between mean platelet volume/platelet count ratio and post-thrombolytic early neurological deterioration in patients with mild and moderate stroke
CONCLUSION: An inverted U-shaped relationship between MPV/PC ratio on admission and post-thrombolytic END was identified in patients with mild and moderate stroke, with a threshold MPV/PC ratio of 51.0. The MPV/PC ratio closer to the threshold was associated with a higher risk of post-thrombolytic END.PMID:36305144 | DOI:10.2174/1567202620666221027093103
Source: Current Neurovascular Research - October 28, 2022 Category: Neurology Authors: Wei Xu Hongquan Guo Huiping Li Kangping Song Fangyi Li Zhen Wang Xinfeng Liu Source Type: research

Efficacy and safety of alteplase on treatment of acute single small subcortical infarction
CONCLUSION: Patients with SSSI in the anterior circulation are more likely to achieve 3 months favorable outcomes than those who were treated with standard medical care, however treatment with alteplase may not prevent occurrence of END.PMID:36043775 | DOI:10.2174/1567202619666220829111211
Source: Current Neurovascular Research - August 31, 2022 Category: Neurology Authors: Kilanga Marcelinus Hongbing Liu Ke Zhang Ce Zong Hongxun Yang Yuan Gao Bo Song Yuming Xu Source Type: research