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Source: Atherosclerosis
Condition: Thrombosis
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Total 704 results found since Jan 2013.
French National Diagnostic and Care Protocol for antiphospholipid syndrome in adults and children
Rev Med Interne. 2023 Sep 19:S0248-8663(23)00711-7. doi: 10.1016/j.revmed.2023.08.004. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is a chronic autoimmune disease involving vascular thrombosis and/or obstetric morbidity and persistent antibodies to phospholipids or certain phospholipid-associated proteins. It is a rare condition in adults and even rarer in children. The diagnosis of APS can be facilitated by the use of classification criteria based on a combination of clinical and biological features. APS may be rapidly progressive with multiple, often synchronous thromboses, resulting in life-threatening...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Z Amoura B Bader-Meunier C Bal Dit Sollier A Belot Y Benhamou H Bezanahary F Cohen N Costedoat-Chalumeau L Darnige L Drouet E Elefant A Harroche M Lambert T Martin I Martin-Toutain A Mathian A Mekinian M Pineton De Chambrun L de Pontual D Wahl C Yelnik S Source Type: research
Assessing Abdominal Aortic Aneurysm Progression by Using Perivascular Adipose Tissue Attenuation on Computed Tomography Angiography
CONCLUSION: Elevated PVAT attenuation is independently associated with AAA progression, including patients of AAA with ILT, suggesting the potential of PVAT attenuation as a predictive imaging marker for AAA expansion.PMID:37724591 | DOI:10.3348/kjr.2023.0339
Source: Atherosclerosis - September 19, 2023 Category: Cardiology Authors: Shuai Zhang Hui Gu Na Chang Sha Li Tianqi Xu Menghan Liu Ximing Wang Source Type: research
Melatonin as a therapeutic agent for alleviating endothelial dysfunction in cardiovascular diseases: Emphasis on oxidative stress
Biomed Pharmacother. 2023 Sep 16;167:115475. doi: 10.1016/j.biopha.2023.115475. Online ahead of print.ABSTRACTThe vascular endothelium is vital in maintaining cardiovascular health by regulating vascular permeability and tone, preventing thrombosis, and controlling vascular inflammation. However, when oxidative stress triggers endothelial dysfunction, it can lead to chronic cardiovascular diseases (CVDs). This happens due to oxidative stress-induced mitochondrial dysfunction, inflammatory responses, and reduced levels of nitric oxide. These factors cause damage to endothelial cells, leading to the acceleration of CVD progr...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Xiaolu Zhang Yujia Zheng Ziyu Wang Jiali Gan Bin Yu Bin Lu Xijuan Jiang Source Type: research
An Update on Inflammation in Atherosclerosis: How to Effectively Treat Residual Risk
This study reviewed the contribution of inflammation to atherosclerotic cardiovascular disease (ASCVD), which has gained widespread recognition in recent years.METHODS: This critical review evaluated how recent publications and ongoing clinical trials in atherosclerotic inflammation will affect clinical care.FINDINGS: Key trials, including CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcomes Study) with canakinumab (interleukin-1β inhibition), and COLCOT (Colchicine Cardiovascular Outcomes Trial) and LoDoCo2 (Low Dose Colchicine 2) with colchicine, have shown that suppressing inflammation can improve outcomes in ASCV...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: N Mohammadnia T S J Opstal S El Messaoudi W A Bax J H Cornel Source Type: research
Short Versus Long Duration of Dual Antiplatelet Therapy After Second-Generation Drug-Eluting Stents Implantation in Patients with Diabetes
CONCLUSION: This meta-analysis showed no statistically significant benefit of longer DAPT over shorter DAPT therapy in patients undergoing PCI with drug-eluting stent in patients with diabetes.PMID:37713685 | DOI:10.1097/MJT.0000000000001519
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Manesh Kumar Gangwani Muhammad Aziz Paul Chacko Asif Mahmood Muhammad Ali Fnu Priyanka Siraj Munir Abeer Aziz Shazib Sagheer Wade Lee-Smith Om Parkash Devesh Rai Bipul Baibhav Wilbert S Aronow Source Type: research
Oral microbiome mediated inflammation, a potential inductor of vascular diseases: a comprehensive review
Front Cardiovasc Med. 2023 Aug 30;10:1250263. doi: 10.3389/fcvm.2023.1250263. eCollection 2023.ABSTRACTThe dysbiosis of the oral microbiome and vascular translocation of the periodontopathic microorganism to peripheral blood can cause local and systemic extra-oral inflammation. Microorganisms associated with the subgingival biofilm are readily translocated to the peripheral circulation, generating bacteremia and endotoxemia, increasing the inflammation in the vascular endothelium and resulting in endothelial dysfunction. This review aimed to demonstrate how the dysbiosis of the oral microbiome and the translocation of oral...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Diego F Gualtero Gloria In és Lafaurie Diana Marcela Buitrago Yormaris Castillo Paula Katherine Vargas-Sanchez Diana Marcela Castillo Source Type: research
Short Versus Long Duration of Dual Antiplatelet Therapy After Second-Generation Drug-Eluting Stents Implantation in Patients with Diabetes
CONCLUSION: This meta-analysis showed no statistically significant benefit of longer DAPT over shorter DAPT therapy in patients undergoing PCI with drug-eluting stent in patients with diabetes.PMID:37713685 | DOI:10.1097/MJT.0000000000001519
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Manesh Kumar Gangwani Muhammad Aziz Paul Chacko Asif Mahmood Muhammad Ali Fnu Priyanka Siraj Munir Abeer Aziz Shazib Sagheer Wade Lee-Smith Om Parkash Devesh Rai Bipul Baibhav Wilbert S Aronow Source Type: research
Oral microbiome mediated inflammation, a potential inductor of vascular diseases: a comprehensive review
Front Cardiovasc Med. 2023 Aug 30;10:1250263. doi: 10.3389/fcvm.2023.1250263. eCollection 2023.ABSTRACTThe dysbiosis of the oral microbiome and vascular translocation of the periodontopathic microorganism to peripheral blood can cause local and systemic extra-oral inflammation. Microorganisms associated with the subgingival biofilm are readily translocated to the peripheral circulation, generating bacteremia and endotoxemia, increasing the inflammation in the vascular endothelium and resulting in endothelial dysfunction. This review aimed to demonstrate how the dysbiosis of the oral microbiome and the translocation of oral...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Diego F Gualtero Gloria In és Lafaurie Diana Marcela Buitrago Yormaris Castillo Paula Katherine Vargas-Sanchez Diana Marcela Castillo Source Type: research
Assessment of Complex Flow Patterns in Patients With Carotid Webs, Patients With Carotid Atherosclerosis, and Healthy Subjects Using 4D Flow MRI
CONCLUSION: Lower TAWSS and higher OSI are present in the ICA bulb in patients with CaW when compared to patients with atherosclerotic or healthy subjects.EVIDENCE LEVEL: 2 TECHNICAL EFFICACY: Stage 2.PMID:37706274 | DOI:10.1002/jmri.29013
Source: Atherosclerosis - September 14, 2023 Category: Cardiology Authors: Retta El Sayed Charlie C Park Zahraw Shah Fadi B Nahab Diogo C Haussen Jason W Allen John N Oshinski Source Type: research
Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19
Life Sci Alliance. 2023 Sep 12;6(11):e202302106. doi: 10.26508/lsa.202302106. Print 2023 Nov.ABSTRACTPreviously, we and others have shown that SARS-CoV-2 spike-specific IgG antibodies play a major role in disease severity in COVID-19 by triggering macrophage hyperactivation, disrupting endothelial barrier integrity, and inducing thrombus formation. This hyperinflammation is dependent on high levels of anti-spike IgG with aberrant Fc tail glycosylation, leading to Fcγ receptor hyperactivation. For development of immune-regulatory therapeutics, drug specificity is crucial to counteract excessive inflammation whereas simulta...
Source: Atherosclerosis - September 12, 2023 Category: Cardiology Authors: Chiara E Geyer Hung-Jen Chen Alexander P Bye Xue D Manz Denise Guerra Tom G Caniels Tom Pl Bijl Guillermo R Griffith Willianne Hoepel Steven W de Taeye Jennifer Veth Alexander Pj Vlaar Amsterdam UMC COVID-19 Biobank Gestur Vidarsson Harm Jan Bogaard Jurja Source Type: research
Phase-transited lysozyme nanofilm with co-immobilized copper ion and heparin as cardiovascular stent multifunctional coating
Colloids Surf B Biointerfaces. 2023 Sep 2;230:113530. doi: 10.1016/j.colsurfb.2023.113530. Online ahead of print.ABSTRACTCardiovascular metal stents have shown potential in the treatment of coronary artery disease using percutaneous coronary intervention. However, thrombosis, endothelialization, and new atherosclerosis after stent implantation remain unsolved problems. Herein, a multifunctional coating material based on phase-transited lysozyme was developed to promote stent endothelialization and simultaneously reduce thrombus events by embedding moieties of heparin and co-immobilized copper ions for in-situ catalyzing ni...
Source: Atherosclerosis - September 8, 2023 Category: Cardiology Authors: Lehua Xu Chenlong He Shusheng Yang Yunxia Zhu Peng Wang Shengming Wu Fangfang Guo Yilong Wang Source Type: research
