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Condition: Stroke
Procedure: MRI Scan

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Total 6681 results found since Jan 2013.

Streamlined Hyperacute Magnetic Resonance Imaging Protocol Identifies Tissue-Type Plasminogen Activator-Eligible Stroke Patients When Clinical Impression Is Stroke Mimic Clinical Sciences
Conclusions— A streamlined hMRI protocol permitted tPA administration to a small, but significant, subset of AIS patients initially considered to have SM.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Goyal, M. S., Hoff, B. G., Williams, J., Khoury, N., Wiesehan, R., Heitsch, L., Panagos, P., Vo, K. D., Benzinger, T., Derdeyn, C. P., Lee, J.-M., Ford, A. L. Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Association Between Time From Stroke Onset and Fluid-Attenuated Inversion Recovery Lesion Intensity Is Modified by Status of Collateral Circulation Clinical Sciences
Conclusions— Our findings show that the relationship between time from symptom onset and rFLAIR lesion intensity depends on collateral status. In patients with good collaterals, the development of an rFLAIR-positive lesion is less dependent on time from symptom onset compared with patients with poor collaterals.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Wouters, A., Dupont, P., Christensen, S., Norrving, B., Laage, R., Thomalla, G., Albers, G., Thijs, V., Lemmens, R. Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Impaired Arm Function and Finger Dexterity in a Nonhuman Primate Model of Stroke: Motor and Cognitive Assessments Basic Sciences
Conclusions— The reported nonhuman primate model produces a defined and reproducible syndrome relevant to our understanding of ischemic stroke, cortical representation, and sensorimotor integration controlling dexterous movements. This model will be useful in basic and translational research addressing loss of arm function and dexterity.
Source: Stroke - March 27, 2016 Category: Neurology Authors: McEntire, C. R. S., Choudhury, G. R., Torres, A., Steinberg, G. K., Redmond, D. E., Daadi, M. M. Tags: Animal Models of Human Disease, Translational Studies, Ischemic Stroke Basic Sciences Source Type: research

Echoing Plaque Activity of the Coronary and Intracranial Arteries in Patients With Stroke Clinical Sciences
Conclusions— Plaques within the intracranial and coronary arteries behave in similar ways. Our results suggest the need to evaluate and treat other vascular trees in patients with vulnerable plaques within a single arterial system.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Chung, J.-W., Bang, O. Y., Lee, M. J., Hwang, J., Cha, J., Choi, J.-H., Choe, Y. H. Tags: Cerebrovascular Disease/Stroke, Atherosclerosis, Coronary Artery Disease Clinical Sciences Source Type: research

Does Contralesional Hand Function After Neonatal Stroke Only Depend on Lesion Characteristics? Brief Reports
Conclusions— Contralesional hand performance after neonatal arterial ischemic stroke is correlated with atrophy in brain areas directly or functionally connected but anatomically remote from the infarct. Our study suggests a role of the cerebellar lobule VIIa Crus I and mediodorsal thalamus in manual dexterity. Clinical Trial Registration— URL: https://clinicaltrials.gov. Unique identifier: NCT02511249.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Dinomais, M., Hertz-Pannier, L., Groeschel, S., Delion, M., Husson, B., Kossorotoff, M., Renaud, C., Chabrier, S., The Tich, S. N., on behalf of the AVCnn Study Group Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Brief Reports Source Type: research

ASPECTS (Alberta Stroke Program Early CT Score) Assessment of the Perfusion-Diffusion Mismatch Clinical Sciences
Conclusions— The mismatch-ASPECTS method can detect a true mismatch in patients with acute middle cerebral artery stroke. It could be used for rapid screening of patients with eligible mismatch, in centers not equipped with ultrafast postprocessing software.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Lassalle, L., Turc, G., Tisserand, M., Charron, S., Roca, P., Lion, S., Legrand, L., Edjlali, M., Naggara, O., Meder, J.-F., Mas, J.-L., Baron, J.-C., Oppenheim, C. Tags: Magnetic Resonance Imaging (MRI), Revascularization, Ischemic Stroke Clinical Sciences Source Type: research

Successful Reperfusion With Mechanical Thrombectomy Is Associated With Reduced Disability and Mortality in Patients With Pretreatment Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score
Background and Purpose—In acute ischemic stroke patients, diffusion-weighted imaging (DWI)–Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is correlated with infarct volume and is an independent factor of functional outcome. Patients with pretreatment DWI-ASPECTS ≤6 were excluded or under-represented in the recent randomized mechanical thrombectomy trials. Our aim was to assess the impact of reperfusion in pretreatment DWI-ASPECTS ≤6 patients treated with mechanical thrombectomy.Methods—We analyzed data collected between January 2012 and August 2015 in a bicentric prospective clinical registry of...
Source: Stroke - March 27, 2017 Category: Neurology Authors: Jean–Philippe Desilles, Arthuro Consoli, Hocine Redȷem, Oguzhan Coskun, Gabriele Ciccio, Stanislas Smaȷda, Julien Labreuche, Cristian Preda, Clara Ruiz Guerrero, Jean–Pierre Decroix, Georges Rodesch, Mikael Mazighi, Raphael Blanc Tags: Magnetic Resonance Imaging (MRI), Revascularization, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Clinical Significance of Wall Changes After Recanalization Therapy in Acute Stroke Brief Report
Conclusions—The use of high-resolution vessel wall imaging after successful recanalization can provide information about postrecanalization arterial wall changes and clinical outcomes.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Woo-Keun Seo, Kyungmi Oh, Sang-il Suh, Hae Young Seol Tags: Magnetic Resonance Imaging (MRI), Quality and Outcomes, Cerebrovascular Procedures, Ischemic Stroke Brief Reports Source Type: research

Proportional Recovery From Lower Limb Motor Impairment After Stroke Brief Report
Conclusions—LL impairment resolves by ≈70% within 3 months after stroke. The absence of a nonfitter group may be because of differences in the neuroanatomical organization of descending motor tracts to the upper limb and LL. Proportional recovery of the LL is not influenced by therapy dose providing further evidence that it reflects a fundamental biological process.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Marie-Claire Smith, Winston D. Byblow, P. Alan Barber, Cathy M. Stinear Tags: Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Structural Integrity of Normal Appearing White Matter and Sex-Specific Outcomes After Acute Ischemic Stroke Brief Report
Background and Purpose—Women have worse poststroke outcomes than men. We evaluated sex-specific clinical and neuroimaging characteristics of white matter in association with functional recovery after acute ischemic stroke.Methods—We performed a retrospective analysis of acute ischemic stroke patients with admission brain MRI and 3- to 6-month modified Rankin Scale score. White matter hyperintensity and acute infarct volume were quantified on fluid-attenuated inversion recovery and diffusion tensor imaging MRI, respectively. Diffusivity anisotropy metrics were calculated in normal appearing white matter contralateral to...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Mark R. Etherton, Ona Wu, Pedro Cougo, Anne-Katrin Giese, Lisa Cloonan, Kaitlin M. Fitzpatrick, Allison S. Kanakis, Gregoire Boulouis, Hasan H. Karadeli, Arne Lauer, Jonathan Rosand, Karen L. Furie, Natalia S. Rost Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke Brief Reports Source Type: research

Outcome After Reperfusion Therapies in Patients With Large Baseline Diffusion-Weighted Imaging Stroke Lesions Brief Report
Conclusions—Stroke patients with DWI lesion>70 mL may benefit from reperfusion therapy, especially those with isolated M1 occlusion or ischemia restricted to the superficial middle cerebral artery territory. The benefit of treatment seems questionable for patients with carotid occlusion or lesion extending to the deep middle cerebral artery territory.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Vincent Gautheron, Yu Xie, Marie Tisserand, Helene Raoult, Sebastien Soize, Olivier Naggara, Romain Bourcier, Sebastien Richard, Francis Guillemin, Serge Bracard, Catherine Oppenheim Tags: Magnetic Resonance Imaging (MRI), Prognosis, Revascularization, Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research

Human Neural Stem Cell Extracellular Vesicles Improve Recovery in a Porcine Model of Ischemic Stroke Basic Sciences
Conclusions—This study demonstrated for the first time that in a large animal model novel NSC EVs significantly improved neural tissue preservation and functional levels post-MCAO, suggesting NSC EVs may be a paradigm changing stroke therapeutic.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Robin L. Webb, Erin E. Kaiser, Brian J. Jurgielewicz, Samantha Spellicy, Shelley L. Scoville, Tyler A. Thompson, Raymond L. Swetenburg, David C. Hess, Franklin D. West, Steven L. Stice Tags: Animal Models of Human Disease, Basic Science Research, Translational Studies, Treatment, Ischemic Stroke Original Contributions Source Type: research

Antiplatelet Treatment After Transient Ischemic Attack and Ischemic Stroke in Patients With Cerebral Microbleeds in 2 Large Cohorts and an Updated Systematic Review Clinical Sciences
Background and Purpose—In patients with transient ischemic attack/ischemic stroke, microbleed burden predicts intracerebral hemorrhage (ICH), and ischemic stroke, but implications for antiplatelet treatment are uncertain. Previous cohort studies have had insufficient follow-up to assess the time course of risks, have not stratified risks by antithrombotic use, and have not reported extracranial bleeds or functional outcome of ICH versus ischemic stroke.Methods—In 2 independent prospective cohorts with transient ischemic attack/ischemic stroke (Oxford Vascular Study/mainly white; University of Hong Kong/mainly Chinese),...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Kui Kai Lau, Caroline E. Lovelock, Linxin Li, Michela Simoni, Sergei Gutnikov, Wilhelm Kuker, Henry Ka Fung Mak, Peter M. Rothwell Tags: Magnetic Resonance Imaging (MRI), Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Multiparametric MRI and CT Models of Infarct Core and Favorable Penumbral Imaging Patterns in Acute Ischemic Stroke Original Contributions
Conclusions— Multiparametric voxel-based MRI and CT models were developed to predict the extent of infarct core and overall penumbral pattern status in patients with acute ischemic stroke who may be candidates for late recanalization therapies. These models provide an alternative approach to mismatch in predicting ultimate tissue fate.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Kidwell, C. S., Wintermark, M., De Silva, D. A., Schaewe, T. J., Jahan, R., Starkman, S., Jovin, T., Hom, J., Jumaa, M., Schreier, J., Gornbein, J., Liebeskind, D. S., Alger, J. R., Saver, J. L. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Original Contributions Source Type: research

Smoking-Thrombolysis Paradox: Recanalization and Reperfusion Rates After Intravenous Tissue Plasminogen Activator in Smokers With Ischemic Stroke Original Contributions
Conclusions— Smoking is independently associated with recanalization and reperfusion, indicating that thrombolytic therapy acts more effectively in smokers; because of small numbers, these results should be considered preliminary. Clinical Trial Registration— URL: http://clinicaltrials.gov. Unique Identifier: NCT00715533.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Kufner, A., Nolte, C. H., Galinovic, I., Brunecker, P., Kufner, G. M., Endres, M., Fiebach, J. B., Ebinger, M. Tags: Fibrinolysis, Angiography, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke, Thrombolysis Original Contributions Source Type: research