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Source: The Lancet Neurology
Condition: Stroke
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Total 244 results found since Jan 2013.
The global burden of stroke: persistent and disabling
Publication date: Available online 11 March 2019Source: The Lancet NeurologyAuthor(s): Philip B Gorelick
Source: The Lancet Neurology - March 12, 2019 Category: Neurology Source Type: research
News from the International Stroke Conference, 2019
Publication date: April 2019Source: The Lancet Neurology, Volume 18, Issue 4Author(s): Helen Frankish
Source: The Lancet Neurology - March 16, 2019 Category: Neurology Source Type: research
Stroke epidemiology in China: which are the next steps?
Publication date: April 2019Source: The Lancet Neurology, Volume 18, Issue 4Author(s): Michael Brainin
Source: The Lancet Neurology - March 16, 2019 Category: Neurology Source Type: research
Reperfusion in acute ischaemic stroke by sonothrombolysis
Publication date: April 2019Source: The Lancet Neurology, Volume 18, Issue 4Author(s): Maxime Gauberti
Source: The Lancet Neurology - March 16, 2019 Category: Neurology Source Type: research
Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial
Publication date: Available online 18 March 2019Source: The Lancet NeurologyAuthor(s): Magdy Selim, Lydia D Foster, Claudia S Moy, Guohua Xi, Michael D Hill, Lewis B Morgenstern, Steven M Greenberg, Michael L James, Vineeta Singh, Wayne M Clark, Casey Norton, Yuko Y Palesch, Sharon D Yeatts, Monica Dolan, Erlinda Yeh, Kevin Sheth, Kimberly Kunze, Susanne Muehlschlegel, Iryna Nieto, Jan ClaassenSummaryBackgroundIron from haemolysed blood is implicated in secondary injury after intracerebral haemorrhage. We aimed to assess the safety of the iron chelator deferoxamine mesylate in patients with intracerebral haemorrhage and to...
Source: The Lancet Neurology - March 19, 2019 Category: Neurology Source Type: research
Small vessel disease: mechanisms and clinical implications
Publication date: Available online 13 May 2019Source: The Lancet NeurologyAuthor(s): Joanna M Wardlaw, Colin Smith, Martin DichgansSummarySmall vessel disease is a disorder of cerebral microvessels that causes white matter hyperintensities and several other common abnormalities (eg, recent small subcortical infarcts and lacunes) seen on brain imaging. Despite being a common cause of stroke and vascular dementia, the underlying pathogenesis is poorly understood. Research in humans has identified several manifestations of cerebral microvessel endothelial dysfunction including blood–brain barrier dysfunction, impaired vasod...
Source: The Lancet Neurology - May 14, 2019 Category: Neurology Source Type: research
The uncertain role for phosphodiesterase inhibitors in stroke prevention
Publication date: June 2019Source: The Lancet Neurology, Volume 18, Issue 6Author(s): Michael D Hill, Oscar R Benavente
Source: The Lancet Neurology - May 22, 2019 Category: Neurology Source Type: research
Dopamine for motor recovery after stroke: where to from here?
Publication date: June 2019Source: The Lancet Neurology, Volume 18, Issue 6Author(s): Cathy M Stinear
Source: The Lancet Neurology - May 22, 2019 Category: Neurology Source Type: research
Adding stroke to the political agenda in Europe
Publication date: June 2019Source: The Lancet Neurology, Volume 18, Issue 6Author(s): The Lancet Neurology
Source: The Lancet Neurology - May 22, 2019 Category: Neurology Source Type: research
Can cerebral microbleeds predict stroke recurrence?
Publication date: Available online 23 May 2019Source: The Lancet NeurologyAuthor(s): Georgios Tsivgoulis, Aristeidis H Katsanos
Source: The Lancet Neurology - May 23, 2019 Category: Neurology Source Type: research
The pathway towards an effective reduction of stroke burden worldwide: teamwork
Publication date: July 2019Source: The Lancet Neurology, Volume 18, Issue 7Author(s): Gustavo Saposnik, Vladimir Hachinski
Source: The Lancet Neurology - June 13, 2019 Category: Neurology Source Type: research
Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: a preplanned pooled analysis of individual participant data
Publication date: September 2019Source: The Lancet Neurology, Volume 18, Issue 9Author(s): Tom J Moullaali, Xia Wang, Reneé H Martin, Virginia B Shipes, Thompson G Robinson, John Chalmers, Jose I Suarez, Adnan I Qureshi, Yuko Y Palesch, Craig S AndersonSummaryBackgroundUncertainty persists over the effects of blood pressure lowering in acute intracerebral haemorrhage. We aimed to combine individual patient-level data from the two largest randomised controlled trials of blood pressure lowering strategies in patients with acute intracerebral haemorrhage to determine the strength of associations between key measures of systo...
Source: The Lancet Neurology - August 8, 2019 Category: Neurology Source Type: research
Computerised speech and language therapy in post-stroke aphasia
Publication date: September 2019Source: The Lancet Neurology, Volume 18, Issue 9Author(s): Agnes Flöel
Source: The Lancet Neurology - August 8, 2019 Category: Neurology Source Type: research
Long-term antithrombotic therapy and risk of intracranial haemorrhage from cerebral cavernous malformations: a population-based cohort study, systematic review, and meta-analysis
Publication date: Available online 7 August 2019Source: The Lancet NeurologyAuthor(s): Susanna M Zuurbier, Charlotte R Hickman, Christos S Tolias, Leon A Rinkel, Rebecca Leyrer, Kelly D Flemming, David Bervini, Giuseppe Lanzino, Robert J Wityk, Hans-Martin Schneble, Ulrich Sure, Rustam Al-Shahi Salman, Scottish Audit of Intracranial Vascular Malformations Steering CommitteeSummaryBackgroundAntithrombotic (anticoagulant or antiplatelet) therapy is withheld from some patients with cerebral cavernous malformations, because of uncertainty around the safety of these drugs in such patients. We aimed to establish whether antithro...
Source: The Lancet Neurology - August 8, 2019 Category: Neurology Source Type: research
Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective multicentre study
This study is registered with ClinicalTrials.gov, number NCT02119182.FindingsBetween Feb 26, 2014, and June 15, 2018, we recruited 450 patients with normal head CT scans (of whom 330 had negative MRI scans and 120 had positive MRI scans), 122 orthopaedic trauma controls, and 209 healthy controls. AUC for GFAP in patients with CT-negative and MRI-positive findings versus patients with CT-negative and MRI-negative findings was 0·777 (95% CI 0·726–0·829) over 24 h. Median plasma GFAP concentration was highest in patients with CT-negative and MRI-positive findings (414·4 pg/mL, 25–75th percentile 139·3–813·4), foll...
Source: The Lancet Neurology - August 24, 2019 Category: Neurology Source Type: research
