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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Stroke

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Total 6741 results found since Jan 2013.

Post-stroke pneumonia: Factors associated with readmission within 90 days of stroke discharge
Stroke is the fifth leading cause of death and a leading cause of disability within the United States.1,2 On average, a stroke occurs every 40 seconds and accounts for approximately 1 in every 19 deaths.2 The prevalence of stroke is projected to increase by 20.5% from 2012 to 2030.2 Post-stroke complications are prevalent; infection occurs among 30% of acute cases.3 Pneumonia is one of the most common post-stroke infections and is associated with increased morbidity.4,5 Moreover, pneumonia is recognized as an independent risk factor for stroke-related mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - August 21, 2023 Category: Neurology Authors: Tiffany Bouddhara, LeighAnn Persondek, Elizabeth Ablah, Hayrettin Okut, Liuqiang Lu, James Walker Source Type: research

Tissue Plasminogen Activator Thrombolytic Therapy for Acute Ischemic Stroke in 4 Hospital Groups in Japan
In October 2005 in Japan, the recombinant tissue plasminogen activator (tPA) alteplase was approved for patients with acute ischemic stroke within 3 hours of onset at a dose of 0.6 mg/kg. The present study was undertaken to assess the safety and efficacy of alteplase in Japan. Between October 2005 and December 2009, a total of 114 consecutive patients admitted to 4 hospitals received intravenous tPA within 3 hours of stroke onset. Clinical backgrounds and outcomes were investigated. The patients were divided into 2 chronological groups: an early group, comprising 45 patients treated between October 2005 and December 2007,...
Source: Journal of Stroke and Cerebrovascular Diseases - October 4, 2011 Category: Neurology Authors: Syoichiro Kono, Kentaro Deguchi, Nobutoshi Morimoto, Tomoko Kurata, Shoko Deguchi, Tohru Yamashita, Yoshio Ikeda, Tohru Matsuura, Hisashi Narai, Nobuhiko Omori, Yasuhiro Manabe, Taijyun Yunoki, Yoshiki Takao, Sanami Kawata, Kenichi Kashihara, Koji Abe Tags: Original Articles Source Type: research

Demographic, Clinical, and Radiologic Predictors of Neurologic Deterioration in Patients with Acute Ischemic Stroke
One-third of patients with acute ischemic stroke develop early neurologic worsening, which is associated with increased mortality and long-term functional disability. We investigated the predictive factors for neurologic deterioration in patients with acute ischemic stroke within 1 week of onset. We retrospectively investigated 643 patients who were admitted within 2 days of acute ischemic stroke between April 2007 and March 2010. Neurologic deterioration was defined as an increase of 4 points or more in the National Institutes of Health Stroke Scale (NIHSS) score within 1 week of admission. We retrieved data on demograph...
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2011 Category: Neurology Authors: Nobukazu Miyamoto, Yasutaka Tanaka, Yuji Ueno, Miyako Kawamura, Yoshiaki Shimada, Ryota Tanaka, Nobutaka Hattori, Takao Urabe Tags: Original Articles Source Type: research

Survival and Differentiation of Transplanted Neural Stem Cells Derived from Human Induced Pluripotent Stem Cells in A Rat Stroke Model
Conclusions: To our knowledge, this is the first report of transplantation of NSCs derived from human iPSCs in a stroke model. Human iPSC-derived NSCs survived in the postischemic rat brain and appeared to differentiate, primarily into neurons. This cell transplantation approach for stroke appears to be feasible, but further optimization is needed.
Source: Journal of Stroke and Cerebrovascular Diseases - November 14, 2011 Category: Neurology Authors: Matthew B. Jensen, Hongmei Yan, Rajeev Krishnaney-Davison, Abdullah Al Sawaf, Su-Chun Zhang Tags: Original Articles Source Type: research

Remote Assessment of Stroke Using the iPhone 4
This study demonstrates the efficacy of using the relatively inexpensive iPhone 4 in telestroke management. Twenty patients with stroke were assessed at the bedside using an iPhone 4, and each examination was directed remotely on another iPhone 4. Both the physician performing the bedside exam and the remote physician calculated a National Institutes of Health Stroke Scale (NIHSS) score for each patient. Each physician was blinded to the other’s NIHSS score. In the 20 patients assessed, NIHSS scores ranged from 0 to 22. Interrater reliability assessed using the κ statistic demonstrated excellent agreement in 10 items (l...
Source: Journal of Stroke and Cerebrovascular Diseases - October 24, 2011 Category: Neurology Authors: Eric R. Anderson, Bryan Smith, Moges Ido, Michael Frankel Tags: Original Articles Source Type: research

Comparison of the Effects of High- and Low-frequency Repetitive Transcranial Magnetic Stimulation on Upper Limb Hemiparesis in the Early Phase of Stroke
Background: Recently, high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) and low-frequency rTMS (LF-rTMS) are reported to improve motor function significantly in chronic hemiparetic stroke patients. However, few studies have investigated the safety and efficacy of these rTMS modalities introduced during the early phase of stroke. The purpose of this study was to clarify the rTMS modality that is more beneficial for upper limb hemiparesis in the early phase of stroke using a randomized controlled trial.Methods: Twenty-nine patients with a hemispheric stroke lesion in the early phase of stroke were examine...
Source: Journal of Stroke and Cerebrovascular Diseases - December 16, 2011 Category: Neurology Authors: Nobuyuki Sasaki, Saneyuki Mizutani, Wataru Kakuda, Masahiro Abo Tags: Original Articles Source Type: research

Recent Trends in Inpatient Mortality and Resource Utilization for Patients with Stroke in the United States: 2005-2009
Background: The aim of the study is to evaluate recent trends in mortality, length of stay, costs, and charges for patients admitted to the US hospitals with the principal diagnosis of stroke.Methods: This was a retrospective temporal trends study using data from the Nationwide Inpatient Sample from 2005 to 2009.Results: During the study period, there were 2.7 million hospital admissions with the diagnosis of stroke in the United States (470,000 intracerebral hemorrhage, 130,000 subarachnoid hemorrhage, and 2.1 million ischemic strokes). In-hospital mortality decreased from 10.2% in 2005 to 9.0% in 2009 (26.0%-23.0%, 23.4...
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2013 Category: Neurology Authors: Maria Stepanova, Chapy Venkatesan, Laith Altaweel, Alita Mishra, Zobair M. Younossi Tags: Original Articles Source Type: research

Impact of Telemedicine Implementation in Thrombolytic Use for Acute Ischemic Stroke: The University of Pittsburgh Medical Center Telestroke Network Experience
Background: Intravenous thrombolysis is the only therapy for acute ischemic stroke that is approved by the US Food and Drug Association. The use of telemedicine in stroke makes it possible to bring the expertise of academic stroke centers to underserved areas, potentially increasing the quality of stroke care.Methods: All consecutive admissions for stroke were reviewed for 1 year before telemedicine implementation and for variable periods thereafter. A retrospective review identified 2588 admissions for acute stroke between March 2005 and December 2008 at 12 hospitals participating in a telestroke network, including 919 pa...
Source: Journal of Stroke and Cerebrovascular Diseases - March 13, 2013 Category: Neurology Authors: Edilberto Amorim, Min-Mei Shih, Steven A. Koehler, Lori L. Massaro, Syed F. Zaidi, Mouhammad A. Jumaa, Vivek K. Reddy, Maxim D. Hammer, Tudor G. Jovin, Lawrence R. Wechsler Tags: Original Articles Source Type: research

Safety of a “Drip and Ship” Intravenous Thrombolysis Protocol for Patients with Acute Ischemic Stroke
Conclusions: Our “drip and ship” protocol for IVT is safe. The protocol was not associated with an excess of sICH or in-hospital mortality compared with patients who received IVT at the CPSC.
Source: Journal of Stroke and Cerebrovascular Diseases - February 10, 2012 Category: Neurology Authors: Simin Mansoor, Ramin Zand, Ameer Al-Wafai, Mervat N. Wahba, Elias A. Giraldo Tags: Original Articles Source Type: research

Optimal Timing and Duration of Continuous Electrocardiographic Monitoring for Detecting Atrial Fibrillation in Stroke Patients
Conclusions: We suggest that in order to enhance the detection rate of AF, CEM could be generalized in the stroke unit. It must be started early in patients with acute stroke and prolonged over a minimum of 4 days.
Source: Journal of Stroke and Cerebrovascular Diseases - February 20, 2012 Category: Neurology Authors: Laurent Suissa, Sylvain Lachaud, Marie Hélène Mahagne Tags: Original Articles Source Type: research

Safety and Effectiveness of Endovascular Treatment after 6 Hours of Symptom Onset in Patients with Anterior Circulation Ischemic Stroke: A Matched Case Control Study
Conclusions: We did not observe any evidence of benefit in halting neurologic worsening or improving outcomes among patients undergoing endovascular treatment for treatment of an anterior circulation ischemic stroke after 6 hours of symptom onset. Strong evidence of both the safety and efficacy of emergent endovascular treatment when administered to patients with stroke in the anterior circulation is needed.
Source: Journal of Stroke and Cerebrovascular Diseases - October 24, 2012 Category: Neurology Authors: Adnan I. Qureshi, Jefferson T. Miley, Saqib A. Chaudhry, Edouard Semaan, Gustavo J. Rodriguez, M.Fareed K. Suri, Harold P. Adams Tags: Original Articles Source Type: research

Trends in Cancer Diagnoses among Inpatients Hospitalized with Stroke
Background: Cancer, by conferring a hypercoagulable state, may lead to an ischemic stroke. Relatively little is known about the prevalence and evolution of cancer among stroke patients over the last decade.Methods: We used the Nationwide Inpatient Sample to identify discharges with any International Classification of Diseases, Ninth Revision, diagnosis code for cancer and ischemic stroke from 1997 to 2006. We then calculated age-adjusted yearly acute ischemic stroke hospitalization rates among adult populations with and without cancer.Results: Prevalence of cancer among hospitalized stroke patients increased from 1997 to ...
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Nerses Sanossian, Christina Djabiras, William J. Mack, Bruce Ovbiagele Tags: Original Articles Source Type: research

Neutrophil Lymphocyte Ratio as a Predictor of Stroke
Conclusions: The NLR at the time of hospital admission may be a predictor of short-term mortality in acute stroke patients. Because of the routine use and inexpensive nature of hemogram analysis, the NLR should be investigated in future prospective, randomized controlled trials investigating acute stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Serhat Tokgoz, Mehmet Kayrak, Zehra Akpinar, Abdullah Seyithanoğlu, Figen Güney, Betigül Yürüten Tags: Original Articles Source Type: research

Factors Associated with Delays in Seeking Treatment for Stroke Care in Veterans
Conclusions: Race appears to be a key factor associated with an increased likelihood of delays in seeking urgent stroke care in veterans. Future studies need to further examine the complex sociodemographic profile of patients who are most likely to delay seeking care for stroke and to develop interventions to reduce the impact of DST.
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2012 Category: Neurology Authors: Charles Ellis, Rebecca G. Knapp, Gregory E. Gilbert, Leonard E. Egede Tags: Original Articles Source Type: research

The Impact Factors on the Cost and Length of Stay among Acute Ischemic Stroke
Conclusions: Age 65 and over, atrial fibrillation, stroke treatment, and subtypes were the significant predictive factors affecting hospital costs and LOS. Compared to other countries, Taiwan spent the least while Canada had the highest expense. The United States had the shortest LOS (6 days) in contrast to Canada with the longest LOS (34-47 days). Regarding mean daily cost of stroke, the United States had the highest cost per day while China spent the least.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Ying-Chih Huang, Chaur-Jong Hu, Tsong-Hai Lee, Jen-Tsung Yang, Hsu-Huei Weng, Leng Chieh Lin, Shiao-Lin Lai Tags: Original Articles Source Type: research