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Source: The American Journal of Cardiology
Condition: Stroke
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Total 712 results found since Jan 2013.
Relation of CHA2DS2VASC Score with Hemorrhagic Stroke and Mortality in Patients Undergoing Fibrinolytic Therapy for ST Elevation Myocardial Infarction
Hemorrhagic stroke (HS) is a feared complication of Fibrinolytic therapy (FT). Risk assessment scores may help in risk stratification to reduce this complication. Patients (admissions) ≥18 years with a primary diagnosis of STEMI who received systemic thrombolysis were extracted from Nationwide Inpatient Sample database and stratified and compared based on CHA2DS2VASC score 0-3, 4-6 and 7-9 as low, intermediate and high risk respectively. The primary outcomes of interest were hem orrhagic stroke (HS) and mortality.
Source: The American Journal of Cardiology - October 18, 2018 Category: Cardiology Authors: Gbolahan O. Ogunbayo, Robert Pecha, Naoki Misumida, Dustin Hillerson, Ayman Elbadawi, Ahmed Abdel-latif, Claude S. Elayi, Adrian W. Messerli, Susan S. Smyth Source Type: research
Relation of the CHA2DS2-VASc Score to Risk of Thrombotic and Embolic Stroke in Community-Dwelling Individuals Without Atrial Fibrillation (From The Atherosclerosis Risk in Communities ARIC Study)
Recent hospital-based cohort studies found the CHA2DS2-VASc score to be associated with ischemic stroke in individuals without atrial fibrillation (AF). Our aim was to determine the distribution of embolic and thrombotic strokes and association with the CHA2DS2-VASc score, among community-dwelling individuals without AF. We included participants from the Atherosclerosis Risk in Communities (ARIC) Study who attended visit 4 (1996-98) and had no prior AF, stroke, or anticoagulant use (n=10,671). During follow-up through 2008, incident AF cases (n=760) and participants who started warfarin were censored.
Source: The American Journal of Cardiology - November 6, 2018 Category: Cardiology Authors: Ryan J. Koene, M. Chadi Alraies, Faye L. Norby, Elsayed Z. Soliman, Ankit Maheshwari, Gregory Y.H. Lip, Alvaro Alonso, Lin Y. Chen Source Type: research
Extremely low prevalence of Takotsubo cardiomyopathy and transient cardiac dysfunction in stroke patients with T-wave abnormalities
Stone et al. studied an important association about the presence of cerebral T-waves in 800 patients with ischemic stroke1. They demonstrated that about 17 (2.1%) patients presenting with stroke exhibited cerebral T-waves and of those, only 3 patients (18%) with T-wave abnormality have transient systolic dysfunction on echocardiography. Thus overall, only 0.0037% (3 of 800) patients developed Takotsubo cardiomyopathy (TC) in the study group of patients with stroke.1
Source: The American Journal of Cardiology - January 9, 2019 Category: Cardiology Authors: Lovely Chhabra, Nauman Khalid, Pooja Sareen Source Type: research
Comparison of Stroke Risk Stratification Scores for Atrial Fibrillation
Several stroke risk stratification scores have been developed to guide clinical decision making in patients with non valvular atrial fibrillation (AF). The aim of this study was to compare the performance of the CHADS2, CHA2DS2-VASc and R2CHADS2 risk scores to predict stroke.This retrospective cohort study was based on electronic medical records from Clalit Health Services (CHS), the largest payer provider healthcare organization in Israel. Data of CHS members with AF diagnosis between 2004- 2015 were extracted.
Source: The American Journal of Cardiology - March 12, 2019 Category: Cardiology Authors: Meytal Avgil Tsadok, Adi Berliner Senderey, Orna Reges, Morton Leibowitz, Maya Leventer-Roberts, Moshe Hoshen, Moti Haim Source Type: research
Usefulness of CHA2DS2-VASc Score to Predict Stroke Risk Independent of Atrial
We examined whether a CHA2DS2-VASc score predicts stroke risk among individuals without hospital-diagnosed AF and quantified the magnitude of the association in comparison to AF patients. We used data from population-based medical registries (1995 –2005) covering all Danish hospitals to identify patients diagnosed with AF (n=122,980). We matched ≤5 non-AF individuals (n=612,723) to each AF patient on the individual risk factors included in the CHA2DS2-VASc score.
Source: The American Journal of Cardiology - July 14, 2019 Category: Cardiology Authors: Anne Gulbech Ording, Erzs ébet Horváth-Puhó, Paolo Prandoni, Michelle Zippora Leisner, Dóra Körmendiné Farkas, Flemming Hald Steffensen, Morten Olsen, Henrik Toft Sørensen, Morten Schmidt Source Type: research
Usefulness of CHA2DS2-VASc Score to Predict Stroke Risk Independent of Atrial Fibrillation
We examined whether a CHA2DS2-VASc score predicts stroke risk among individuals without hospital-diagnosed AF and quantified the magnitude of the association in comparison to AF patients. We used data from population-based medical registries (1995 to 2005) covering all Danish hospitals to identify patients diagnosed with AF (n = 122,980). We matched ≤5 non-AF individuals (n = 612,723) to each AF patient on the individual risk factors included in the CHA2DS2-VASc score.
Source: The American Journal of Cardiology - July 14, 2019 Category: Cardiology Authors: Anne Gulbech Ording, Erzs ébet Horváth-Puhó, Paolo Prandoni, Michelle Zippora Leisner, Dóra Körmendiné Farkas, Flemming Hald Steffensen, Morten Olsen, Henrik Toft Sørensen, Morten Schmidt Source Type: research
Relation of Advanced Interatrial Block to Risk of Atrial Fibrillation and Stroke
Advanced interatrial block (A-IAB) has been associated to atrial fibrillation (AF) and ischemic stroke, raising the question as to whether such patients, even when still in sinus rhythm without documented AF, could benefit from oral anticoagulation. AF and A-IAB are both markers of stroke. The anatomical substrate in both is fibrotic atrial cardiomyopathy, resulting in atrial electromechanical dyssynchrony, dysfunction, and left atrial remodelling, that favour blood stasis and hypercoagulation. Under these conditions thrombogenic cascade may be triggered, resulting in systemic embolization.
Source: The American Journal of Cardiology - March 16, 2020 Category: Cardiology Authors: Antoni Bay és-de-Luna, Manuel Martínez-Sellés, Roberto Elosua, Antoni Bayés-Genís, Guiomar Mendieta, Adrian Baranchuk, Günter Breithardt Source Type: research
Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤ 50 Years of Age with Laboratory Confirmed COVID-19 Infection
The COVID-19 epidemic has led to an unpreceded disruption in health care systems worldwide. Concerns have been recently raised about young patients with COVID-19 presenting with large ischemic strokes.1 Data on stroke in COVID-19 patients remain limited to a few case reports.1 In this focused analysis, we investigated the incidence and outcomes of acute ischemic stroke in young adults using a multinational database.
Source: The American Journal of Cardiology - June 13, 2020 Category: Cardiology Authors: Frank Annie, Mark C. Bates, Aravinda Nanjundappa, Deepak L. Bhatt, Mohamad Alkhouli Source Type: research
Comparison of Oral Anticoagulant Use and Stroke Risk among Older Adults Newly-Diagnosed Atrial Fibrillation Living in Urban-vs-Rural Areas
We aimed to assess the association between urban/rural residence and the risk of ischemic stroke in individuals with newly diagnosed atrial fibrillation (AF), and to quantify the role of oral anticoagulation (OAC) initiation in the variation in stroke risk between urban and rural residents with AF. Using 5% random samples of Medicare claims, we identified fee-for-service beneficiaries who were diagnosed with AF between January 2014 and December 2015. Beneficiaries were followed for 1 year since their AF diagnosis, and were categorized according to their initiation of OAC within the year.
Source: The American Journal of Cardiology - June 15, 2020 Category: Cardiology Authors: Jingchuan Guo, Meiqi He, Jared W Magnani, Maria M Brooks, Walid F. Gellad, Inmaculada Hernandez Source Type: research
Impact of Diabetes Mellitus on Stroke and Survival in Patients with Atrial Fibrillation
Although diabetes mellitus (DM) has been established as a risk factor for developing atrial fibrillation (AF) and is a known risk factor for stroke, it is unclear whether the presence or duration of DM is the primary adverse influence on the clinical course of AF. We retrospectively analyzed patients diagnosed with incident AF to examine the impact of DM on ischemic stroke and all-cause mortality. The diagnosis of DM was established by ICD-9 codes and review of medical records. To account for the significant differences in baseline characteristics of patients with and without diabetes, we matched 909 AF patients with DM wi...
Source: The American Journal of Cardiology - June 28, 2020 Category: Cardiology Authors: Sri Harsha Patlolla, Hon-Chi Lee, Peter A. Noseworthy, Waldemar E. Wysokinski, David O. Hodge, Eddie L. Greene, Bernard J. Gersh, Rowlens M. Melduni Source Type: research
Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤50 Years of Age With Laboratory Confirmed COVID-19 Infection
The COVID-19 epidemic has led to an unpreceded disruption in health care systems worldwide. Concerns have been recently raised about young patients with COVID-19 presenting with large ischemic strokes.1 Data on stroke in COVID-19 patients remain limited to a few case reports.1 In this focused analysis, we investigated the incidence and outcomes of acute ischemic stroke in young adults using a multinational database.
Source: The American Journal of Cardiology - June 13, 2020 Category: Cardiology Authors: Frank Annie, Mark C. Bates, Aravinda Nanjundappa, Deepak L. Bhatt, Mohamad Alkhouli Source Type: research
Periprocedural Stroke After Coronary Revascularization (From the CREDO-Kyoto PCI/CABG Registry Cohort-3)
There is a scarcity of data on incidence, risk factors, especially clinical severity, and long-term prognostic impact of periprocedural stroke after coronary revascularization in contemporary real-world practice. Among 14867 consecutive patients undergoing first coronary revascularization between January 2011 and December 2013 (percutaneous coronary intervention [PCI]: N=13258, and coronary artery bypass grafting [CABG]: N=1609) in the CREDO-Kyoto PCI/CABG registry Cohort-3, we evaluated the details on periprocedural stroke.
Source: The American Journal of Cardiology - December 3, 2020 Category: Cardiology Authors: Ko Yamamoto, Masahiro Natsuaki, Takeshi Morimoto, Hiroki Shiomi, Yukiko Matsumura-Nakano, Kenji Nakatsuma, Hiroki Watanabe, Erika Yamamoto, Eri Kato, Masayuki Fuki, Kyohei Yamaji, Ryusuke Nishikawa, Kazuya Nagao, Yasuaki Takeji, Hirotoshi Watanabe, Junich Source Type: research
Prevalence of In-hospital Stroke Comparing MitraClip and Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) and mitraclip (MC) are increasingly utilized for the treatment of aortic stenosis (AS) and mitral regurgitation (MR), respectively. Perioperative stroke is one of the most serious complications following TAVI given the valve calcification and possible embolization during valve implantation, and thus ongoing trials are assessing the use of embolic protection device following TAVI. On the other hand, no such trials are being conducted on MC as the evidence of stroke following MC is lacking and MC does not share the same etiology with TAVI 1.
Source: The American Journal of Cardiology - January 5, 2021 Category: Cardiology Authors: Anas M. Saad, Keerat Rai Ahuja, Omar M. Abdelfattah, Mohamed M. Gad, Toshiaki Isogai, Manpreet Kaur, Grant W. Reed, James Yun, Amar Krishnaswamy, Samir R. Kapadia Source Type: research
Relation of Atrial Fibrillation to Cognitive Decline (from the REasons for Geographic and Racial Differences in Stroke REGARDS Study)
The association of atrial fibrillation (AF) with cognitive function remains unclear, especially among racially/geographically diverse populations. This analysis included 25,980 black and white adults, aged 48+, from the national REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort, free from cognitive impairment and stroke at baseline. Baseline AF was identified by self-reported medical history or electrocardiogram (ECG). Cognitive testing was conducted yearly with the Six Item Screener (SIS) to define impairment and at 2-year intervals to assess decline on: animal naming and letter fluency, Montreal Co...
Source: The American Journal of Cardiology - March 5, 2021 Category: Cardiology Authors: Margie J. Bailey, Elsayed Z. Soliman, Leslie A. McClure, George Howard, Virginia J. Howard, Suzanne E. Judd, Fred Unverzagt, Virginia Wadley, Bonnie C. Sachs, Timothy Hughes Source Type: research
Using Thoracic Artery Calcium Score to Predict Stroke
We are very enthused about the concept presented by Obisesan et al.1 regarding the use of thoracic artery calcium (TAC) as a predictor of stroke mortality. The logic on why aortic atherosclerosis is more closely related (to stroke mortality) than coronary artery calcification (CAC) scores is intriguing – we initially expected it to run in parallel but the explanation they give makes good sense. We also really appreciate the practicality – that it can be done easily with the data already acquired.
Source: The American Journal of Cardiology - June 17, 2021 Category: Cardiology Authors: Joseph C. Lee, Sushil Allen Luis, Alaa Alghamry Source Type: research
