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Downregulation of GSK-3 β Expression via Ultrasound-Targeted Microbubble Destruction Enhances Atherosclerotic Plaque Stability in New Zealand Rabbits
Accumulating evidence suggests that atherosclerosis (AS) is the underlying cause of vascular diseases, including heart disease and stroke. Ultrasound-targeted microbubble destruction (UTMD) technology provides a tolerable, efficient and effective system for drug delivery and gene transfection, which has broad application prospects in the treatment of AS. In addition, glycogen synthase kinase (GSK)-3 β has been implicated as a potentially valuable therapeutic agent for AS treatment; however, the specific molecular mechanisms remain unknown.
Source: Ultrasound in Medicine and Biology - November 28, 2020 Category: Radiology Authors: Lifei Yang, Lingzi Chen, Ye Fang, Suya Ma Tags: Original Contribution Source Type: research

Assessment of image quality and dose in contrast-enhanced head and neck CT angiography of New Zealand rabbit.
CONCLUSIONS: Low dose CTA of rabbits with 70 or 80 kVp is feasible in a 256-slice or a 64-slice CT scanner. The radiation dose from the 256-slice CTA was much lower than that from the 64-slice CTA with comparable SNR and CNR. The technique can be further applied in longitudinal monitoring of an animal stroke model in the future. PMID: 32597826 [PubMed - as supplied by publisher]
Source: Journal of X-Ray Science and Technology - July 1, 2020 Category: Radiology Tags: J Xray Sci Technol Source Type: research

The Role of Interventional Radiologists in Acute Stroke Interventions: A Joint Statement from the Australia and New Zealand Society of Neuroradiology (ANZSNR), the Society of Neurointerventional Surgery (SNIS), the United Kingdom Neurointerventional Group (UKNG), the British Society of Neuroradiology (BSNR), and the European Society for Minimally Invasive, Neurological Therapy (ESMINT)
Publication date: September 2019Source: Journal of Vascular and Interventional Radiology, Volume 30, Issue 9Author(s): Jason Wenderoth, William McAuliffe, Alan Coulthard, Peter Mitchell, Adam Arthur, Justin F. Fraser, Norman McConachie, Andrew Clifton, Peter Flynn, Robert Crossley, Patrick Brouwer, Zsolt Kulscar, Jens Fiehler
Source: Journal of Vascular and Interventional Radiology - August 22, 2019 Category: Radiology Source Type: research

The Role of Interventional Radiologists in Acute  Stroke Interventions: A Joint Statement from the Australia and New Zealand Society of Neuroradiology (ANZSNR), the Society of Neurointerventional Surgery (SNIS), the United Kingdom Neurointerventional Group (UKNG), the British Society of Neuroradiology (BSNR), and the European Society for Minimall y Invasive, Neurological Therapy (ESMINT)
We read with interest the article by representatives of European Board of Interventional Radiology, Society of International Radiology, and International RadioSurgery Association (1). The interest of interventional radiologists in mechanical thrombectomy (MT) is welcome, but the cognitive/procedural aspects of MT must be considered along with the complex processes and resources required for service implementation. Training for all proceduralists must be consistent, MT proceduralists ’ posttraining performance must meet satisfactory benchmarks, and MT centers’ outcomes must be acceptable.
Source: Journal of Vascular and Interventional Radiology : JVIR - August 22, 2019 Category: Radiology Authors: Jason Wenderoth, William McAuliffe, Alan Coulthard, Peter Mitchell, Adam Arthur, Justin F. Fraser, Norman McConachie, Andrew Clifton, Peter Flynn, Robert Crossley, Patrick Brouwer, Zsolt Kulscar, Jens Fiehler Tags: Commentary Source Type: research

Standards of practice in acute ischemic stroke intervention: International recommendations: This article was first published in JNIS. Cite this article as: Pierot L, Jayaraman MV, Szikora I, et  al. Standards of practice in acute ischemic stroke intervention: international recommendations. Journal of NeuroInterventional Surgery. Published Online First: 28 August 2018. doi: 10.1136/neurintsurg-2018-014287.
This article was first published in JNIS. Cite this article as: Pierot L, Jayaraman MV, Szikora I, et al. Standards of practice in acute ischemic stroke intervention: international recommendations. Journal of NeuroInterventional Surgery. Published Online First: 28 August 2018. doi: 10.1136/neurintsurg-2018-014287. Interv Neuroradiol. 2018 Oct 23;:1591019918800457 Authors: Pierot L, Jayaraman MV, Szikora I, Hirsch JA, Baxter B, Miyachi S, Mahadevan J, Chong W, Mitchell PJ, Coulthard A, Rowley HA, Sanelli PC, Tampieri D, Brouwer PA, Fiehler J, Kocer N, Vilela P, Rovira A, Fischer U, Caso V, van der Worp B, Saka...
Source: Interventional Neuroradiology - October 27, 2018 Category: Radiology Tags: Interv Neuroradiol Source Type: research