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Vaccination: Malaria Vaccine
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Total 54 results found since Jan 2013.
Safety and Immunogenicity of Radiation-Attenuated PfSPZ Vaccine in Equatoguinean Infants, Children, and Adults
Am J Trop Med Hyg. 2023 May 9:tpmd220773. doi: 10.4269/ajtmh.22-0773. Online ahead of print.ABSTRACTThe radiation-attenuated Plasmodium falciparum sporozoites (PfSPZ) Vaccine has demonstrated safety and immunogenicity in 5-month-old to 50-year-old Africans in multiple trials. Except for one, each trial has restricted enrollment to either infants and children or adults < 50 years old. This trial was conducted in Equatorial Guinea and assessed the safety, tolerability, and immunogenicity of three direct venous inoculations of 1.8 × 106 or 2.7 × 106 PfSPZ, of PfSPZ Vaccine, or normal saline administered at 8-week interva...
Source: The American Journal of Tropical Medicine and Hygiene - May 9, 2023 Category: Tropical Medicine Authors: Said A Jongo Vicente Urbano Nsue Ndong Nchama L W Preston Church Ally Olotu Stephen R Manock Tobias Schindler Ali Mtoro Natasha Kc Orrin Devinsky Elcin Zan Ali Hamad Elizabeth Nyakarungu Maxmillian Mpina Anna Deal Jos é Raso Bijeri Martin Eka Ondo Mangue Source Type: research
Systematic Review of Safety of RTS,S with AS01 and AS02 Adjuvant Systems Using Data from Randomized Controlled Trials in Infants, Children, and Adults
CONCLUSION: Most of the adverse events observed from RTS,S/AS01 and RTS,S/AS02 malaria vaccines were reported in the control group and shared by other vaccines. Hence, the authors concluded that both RTS,S/AS01 and RTS,S/AS02 malaria vaccines are safe.PMID:36941908 | PMC:PMC10024506 | DOI:10.2147/CPAA.S400155
Source: Clinical Pharmacology: Advances and Applications - March 21, 2023 Category: Allergy & Immunology Authors: Wubetu Yihunie Bekalu Kebede Bantayehu Addis Tegegne Melese Getachew Dehnnet Abebe Yibeltal Aschale Habtamu Belew Bereket Bahiru Source Type: research
